Acupressure Intervention to Improve Fatigue and Physical Functioning of Chinese Immigrant Breast Cancer Survivors

穴位按摩干预改善中国移民乳腺癌幸存者的疲劳和身体机能

基本信息

批准号：
9178314
负责人：
Judy Huei-yu Wang
金额：
$ 21.95万
依托单位：
GEORGETOWN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-01 至 2018-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9178314
关键词：
21 year old Acupressure Acupuncture Points Address Adverse effects Affect Aftercare Anxiety Asian Americans Biological Breast Cancer Patient Breast Cancer survivor Cancer Patient Cancer Survivor Cancer Survivorship Caucasians Chinese American Chinese People Chinese Traditional Medicine Clinical Communities Control Groups Data Diagnosis Distal Enrollment Exercise Family Fatigue Generations Goals Home environment Immigrant Incidence Information Systems Intervention Intervention Studies Knowledge Language Learning Life Limited English Proficiency Linguistics Los Angeles Malignant Neoplasms Malignant neoplasm of lung Measurement Mental Depression Methods Minority Neighborhoods Not Hispanic or Latino Occupations Organ Outcome Participant Patient Outcomes Assessments Patients Performance at work Physical Function Play Population Process Productivity Psyche structure Qi Quality of Care Quality of life Randomized Randomized Controlled Trials Reporting Research Resources Security Self-Administered Side Sleep Sleep disturbances Staging Stress Subgroup Survivors Symptoms Telephone Interviews Testing Time Toxic effect Treatment Efficacy United States Woman Work base cancer health disparity cancer type common symptom cost cost effectiveness design efficacy testing experience follow-up functional status improved innovation malignant breast neoplasm meetings neoplasm registry neurochemistry neurotransmitter release post intervention pressure randomized trial socioeconomics sound therapy design treatment as usual treatment strategy

项目摘要

ABSTRACT Minority and immigrant cancer patients are more likely to have poorer physical functioning than Non-Hispanic White patients. Cancer-related fatigue (CRF) is one of the most common symptoms associated with declines in physical functioning. Chinese Americans are the largest subgroup of Asian Americans and the fastest growing immigrant group in the US. Our data suggests that Chinese immigrant breast cancer survivors have poorer physical functioning than NHW survivors; in part because the former are more likely to experience CRF than the latter. Chinese immigrants have fewer socioeconomic resources and experience cultural and linguistic challenges when attempting to access quality care, making their adjustment to cancer even harder. Despite these documented disparities, there are no interventions designed to improve Chinese immigrant survivors’ CRF or physical functioning. Self-administered acupressure, a low-cost and low-toxicity approach originating from Traditional Chinese Medicine, is emerging to help cancer patients reduce CRF and boost energy to meet daily demands at work and home. Therefore, we propose a randomized controlled trial (RCT) to develop and pilot test the efficacy of a home-based, self-administered acupressure intervention in improving CRF (proximal outcome), physical functioning and other quality of life outcomes (distal outcomes) of Chinese immigrant breast cancer survivors (versus usual care control group). We will use the patient-reported outcomes measurement information system (PROMIS®) short forms to assess our outcome variables. Using Los Angeles (LA) cancer registry cases, we will enroll 124 first-generation, Chinese-speaking immigrant women with moderate to severe levels of fatigue, diagnosed with stage 0-III breast cancer, aged 21-69, and 1-5 years post-primary treatment. Based on an adaptive treatment strategy design, participants will be randomized to either the self-acupressure intervention or control groups. The self-acupressure group will learn how to press three chief energy acupoints on each side of the body through a 10-minute Chinese-language video (DVD) and practice self-acupressure every day (one minute per acupoint; a total of 6 minutes per day) for a six-week intervention period. Participants will be telephone interviewed twice: at baseline and 6-weeks post-intervention. The research examining CRF and functional status of Chinese immigrant cancer survivors is lacking, and the impact of self- acupressure on cancer survivorship has not been sufficiently tested. PROMIS® is also underused in immigrant populations. Our proposed intervention study is the first of its kind that we are aware of. Knowledge gained from this study will be significant and innovative in advancing the measurement and intervention approaches of cancer survivorship and directing scientifically sound efforts to reduce cancer disparities experienced by the growing yet underserved Chinese immigrant population.

抽象的少数族裔和移民癌症患者的身体机能比非西班牙裔更有可能白人患者。与癌症有关的疲劳（CRF）是与下降相关的最常见符号之一身体功能。中国美国人是亚裔美国人最大的亚组，也是增长最快的亚洲人美国的移民团体。我们的数据表明，中国移民乳腺癌存活较差身体功能比NHW存活；部分是因为前者比后者。中国移民的社会经济资源较少，并且经验文化和语言试图获得优质护理时面临的挑战，使他们对癌症的调整更加困难。尽管这些记录的分布，没有旨在改善中国移民幸存者的干预措施 CRF或身体功能。自我管理的穴位压力，一种低成本和低毒性的方法从传统中药开始，正在兴起，以帮助癌症患者减少CRF并增加能量以满足每日工作和家庭需求。因此，我们建议一项随机对照试验（RCT）开发和试验测试基于家庭的自我管理的穴位压力干预效率改善CRF（近端）结果），中国移民乳房的身体功能和其他生活质量结果（远端结果）癌症存活（与通常的护理对照组）。我们将使用患者报告的结果测量信息系统（Promis®）简短表格，以评估我们的结果变量。使用洛杉矶（LA）癌症注册案件，我们将注册124次第一代，讲中文的移民妇女中度至重度疲劳水平，被诊断为0-III期乳腺癌，年龄在21 - 69年，后期治疗1 - 5年。基于自适应治疗策略设计，参与者将被随机分为自任服干预或对照组。自任务小组将学习如何按下三个主要的能量穴位通过10分钟的中文视频（DVD）在身体的每一侧，并练习自任务每天（每座一分钟一分钟；每天总共6分钟）进行六周的干预期。参与者将接受两次采访的电话：干预后的基线和6周。研究缺乏检查中国移民癌症存活的CRF和功能状况，而自我的影响癌症生存期的穴位尚未得到充分测试。 PROMIS®在移民中也没有充分利用人群。我们提出的干预研究是我们知道的第一项。知识获得了从这项研究中，将在推进测量和干预方法的重要性和创新性癌症的生存和指导科学良好的努力，以减少由增长但服务不足的中国移民人口。