Dissemination of Patient-Centered Outcomes Research in Hepatitis C Virus to Infec

传播以患者为中心的丙型肝炎病毒感染结果研究

• 批准号: 8464492
• 负责人: David L Thomas
• 金额: $ 10万
• 依托单位: INFECTIOUS DISEASES SOCIETY OF AMERICA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-01 至 2016-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8464492
• 关键词: Dissemination; Patient; Centered; Outcomes; Research

DESCRIPTION (provided by applicant): 1 Dissemination of HCV Patient-Centered Outcomes Research - 2 Background: In the United States, nearly 4 million persons are estimated to be infected with 3 hepatitis C virus (HCV) with approximately 20,000 newly infected cases occurring each year.i,ii 4 Department of Health and Human Services has issued an action plan for the prevention, care 5 and treatment of viral hepatitis which aims to raise awareness of this "silent epidemic" and 6 reduce the number of new HCV infection cases, all in alignment with the Healthy People 2020 7 objectives.iii One major response is supported by recent research into the cost-effectiveness of 8 screening that has led the CDC to formulate new HCV screening guidelines that will call for the 9 testing of every person born 1945-1965. These new guidelines are expected to be released 10 later this year and will markedly increase HCV identification. 11 AHRQ has produced several complementary reviews focused on HCV screening, treatment, 12 and adherence to therapy. The rapid dissemination of this information to ID specialists is the 13 next critical step but requires resources to do so in a timely and effective manner. 14 The overarching goal of this program proposal is to reduce the morbidity and mortality 15 associated with HCV infection by expanding the capacity of ID providers to identify and treat 16 HCV infection. In order to achieve this goal, the IDSA's Hepatitis C Task Force will develop 17 educational programs and resources to assist ID specialists and fellows in the diagnosis, 18 management, and treatment of viral hepatitis. Specifically, the task force will (1) develop in- 19 depth training for ID specialists in the form of self-evaluation knowledge modules; (2) provide 20 training for ID fellows focused on the epidemiology, diagnosis, management, and treatment of 21 HCV, significantly expanding that which they may receive through their training programs; and 22 (3) provide outreach to the primary care community to promote HCV screening guidelines and 23 linkage to care following diagnosis. 24 This proposal will directly support the achievement of two of the Healthy People 2020 goals 25 related to hepatitis C virus - the goal of increasing the awareness of those infected and the goal 26 of decreasing the number of new infections. There is a high likelihood of success given the 27 timing of the rapid changes in the field of HCV and proven capability of IDSA to impact the 28 practice patterns of their membership through educational activities such as the specific 29 measures planned in this proposal. i Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 2006; 144:705-14. ii CDC. Surveillance for acute viral hepatitis-United States, 2008. Available at: http://www.cdc.gov/hepatitis/Statistics/2008Surveillance/index.htm. iii Combating the Silent Epidemic of Viral Hepatitis: Action Plan for Prevention, Care and Treatment of Viral Hepatitis. Department of Health & Human Services. May 12, 2011. Accessed on January, 17, 2012 at http://www.hhs.gov/ash/initiatives/hepatitis

描述（由申请人提供）： 1 以患者为中心的 HCV 结果研究的传播 - 2 背景：在美国，估计有近 400 万人感染 3 种丙型肝炎病毒 (HCV)，每种新感染病例约为 20,000 例年.i,ii 4 卫生与公众服务部发布了预防、护理 5 和治疗病毒性肝炎的行动计划，旨在提高对这种“无声流行病”的认识，并 6 减少病毒性肝炎的发生新的 HCV 感染病例数，均符合“健康人民 2020”7 个目标。iii 最近对筛查成本效益的研究支持了一项重大应对措施，该研究促使 CDC 制定了新的 HCV 筛查指南，该指南将要求对 1945 年至 1965 年出生的每个人进行的 9 项测试。这些新指南预计将于今年晚些时候发布，并将显着提高丙肝病毒的识别率。 11 AHRQ 已发表几项补充审查，重点关注 HCV 筛查、治疗 12 和治疗依从性。向身份识别专家快速传播这些信息是下一个关键步骤 13，但需要资源及时有效地做到这一点。 14 该计划提案的总体目标是通过扩大 ID 提供者识别和治疗 16 HCV 感染的能力来降低与 HCV 感染相关的发病率和死亡率 15 。为了实现这一目标，IDSA 丙型肝炎工作组将开发 17 项教育计划和资源，以协助 ID 专家和研究员进行病毒性肝炎的诊断、18 管理和治疗。具体来说，工作组将（1）以自我评估知识模块的形式，在19年开展ID专家的深度培训； (2) 为 ID 研究员提供 20 次培训，重点关注 21 种 HCV 的流行病学、诊断、管理和治疗，显着扩大他们可以通过培训计划获得的培训内容； 22 (3) 向初级保健社区提供外展活动，以推广 HCV 筛查指南，并 23 与诊断后的护理建立联系。 24 该提案将直接支持实现与丙型肝炎病毒相关的《健康人民 2020》目标 25 中的两项——提高感染者的认识的目标和减少新感染人数的目标 26。鉴于 HCV 领域快速变化的时机以及 IDSA 已证明有能力通过教育活动（例如本提案中计划的具体 29 项措施）影响其会员的 28 种实践模式，成功的可能性很高。我阿姆斯特朗 GL、瓦斯利 A、西马德 EP、麦奎伦 GM、库纳特 WL、阿尔特 MJ。 1999 年至 2002 年美国丙型肝炎病毒感染流行情况。Ann Intern Med 2006； 144：705-14。疾病预防控制中心。急性病毒性肝炎监测——美国，2008 年。参见：http://www.cdc.gov/hepatitis/Statistics/2008Surveillance/index.htm。 iii 抗击病毒性肝炎的无声流行：病毒性肝炎预防、护理和治疗行动计划。 卫生与公众服务部。 2011 年 5 月 12 日。2012 年 1 月 17 日访问：http://www.hhs.gov/ash/initiatives/hepatitis