A Dual Inoculation Approach to Alcohol Prevention Among African American Youth

非裔美国青少年预防酒精双重接种方法

基本信息

批准号：
8595272
负责人：
STEVEN M KOGAN
金额：
$ 64.7万
依托单位：
UNIVERSITY OF GEORGIA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-12-10 至 2017-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8595272
关键词：
11 year old 14 year old Accounting Achievement Address Adolescence Adolescent Affect African American Age Alcohol consumption Attention Behavior Behavioral Cessation of life Childhood Cognitive Cost Effectiveness Analysis Data Development Educational Curriculum Evaluation Event Family Family Research Frequencies Guidelines High School Student Injury Intervention Investigation Lead Link Longitudinal Studies Medical Modeling Morbidity - disease rate Outcome Parents Pattern Prevention Prevention program Prevention strategy Preventive Preventive Intervention Primary Prevention Process Public Health Quality of life Randomized Recruitment Activity Relative (related person)Research Resources Risk Risk Factors Rural Sampling School-Age Population Scientist Series Specific qualifier value Staging Teenagers Testing Thinking Time Translating Vaccines Work Youth alcohol prevention alcohol related problem alcohol use initiation arm base binge drinking cost cost effectiveness design deter alcohol use early adolescence early alcohol use four-arm study high risk high school junior high school meetings mortality novel preadolescence prevent programs psychosocial public health relevance social underage drinking

项目摘要

DESCRIPTION (provided by applicant): The personal and social consequences of underage drinking are extensive, ranging from injury to impaired psychosocial and cognitive development. This proposal addresses the need for a transformation in current thinking regarding the primary prevention of alcohol use among adolescents in general, and rural African American youth in particular. To date, the implementation and evaluation of alcohol use prevention has been limited by an exclusive focus on delivering efficacious interventions during the transition to earl adolescence. This paradigm is based on the assumption that a single inoculation of an efficacious preventive intervention prior to entering middle school is sufficient to deter alcohol use through the high school years. Inclusive reviews reveal, however, that primary prevention programs implemented in preadolescence fail to achieve robust, long-term results. These programs do not address the fact that many youth will begin using alcohol in high school, often rapidly escalating in their use. A preadolescent inoculation of prevention is not sufficient to equp youth for the novel risk processes they will encounter in high school. In contrast, we propose that achievement of public health impact requires a "dual-inoculation" prevention strategy, one that addresses the onset of use in both early adolescence and mid-adolescence and provides developmentally tailored curricula at each developmental stage. Based on longitudinal studies with rural African American families that documented the changing context of alcohol use risk and protective processes from late childhood through adolescence, scientists at the Center for Family Research developed a series of developmentally appropriate, family- centered preventive interventions that have proven efficacious in in preventing alcohol use: the SAAF program for youth age 10-12 and the SAAF-Teen program for youth age 14-16. These programs afford a unique opportunity to test dual-inoculation hypotheses. We propose to test the relative efficacy of a dual inoculation (SAAF + SAAF-Teen) versus a preadolescent inoculation (SAAF only), a mid-adolescent inoculation (SAAF- Teen only), or no inoculations (control) in a four-arm trial with 460 rural African American youth and their parents. This design permits the evaluation of the relative superiority of the dual inoculation as well as providing information about the mechanisms through which intervention-targeted protective processes affect alcohol use behavior. This study represents the first evaluation of a dual-inoculation strategy, one that has the potential to enhance significantly the practice of primary prevention. To further enhance the potential for widespread dissemination of the approach, we propose to conduct cost-effectiveness analysis alongside the prevention trial.

描述（由申请人提供）：未成年人饮酒对个人和社会造成的后果是广泛的，从伤害到社会心理和认知发展受损。该提案解决了当前关于青少年、特别是农村非裔美国青年饮酒一级预防的思维转变的需要。迄今为止，预防饮酒的实施和评估仅限于在青春期早期过渡期间提供有效的干预措施。该范式基于这样的假设：在进入中学之前接种一次有效的预防干预措施就足以阻止整个高中时期的饮酒。然而，包容性审查表明，在青春期前实施的初级预防计划未能取得稳健的长期结果。这些计划并没有解决许多青少年在高中就开始饮酒，而且饮酒量往往迅速升级的事实。青春期前的预防接种不足以让青少年做好应对高中时将遇到的新风险过程的准备。相比之下，我们建议，要实现公共卫生影响，需要采取“双重接种”预防策略，即解决青春期早期和青春期中期开始使用的问题，并在每个发育阶段提供适合发育的课程。基于对农村非裔美国家庭的纵向研究，记录了从童年晚期到青春期的饮酒风险和保护过程的变化背景，家庭研究中心的科学家开发了一系列适合发展、以家庭为中心的预防干预措施，这些干预措施已被证明是有效的预防饮酒：针对 10-12 岁青少年的 SAAF 计划和针对 14-16 岁青少年的 SAAF-青少年计划。这些计划为检验双重接种假设提供了独特的机会。我们建议在四臂试验中测试双重接种（SAAF + SAAF-Teen）与青春期前接种（仅 SAAF）、青春期中期接种（仅 SAAF-Teen）或不接种（对照）的相对功效对 460 名农村非裔美国青年及其父母进行的试验。这种设计可以评估双重接种的相对优越性，并提供有关干预目标保护过程影响饮酒行为的机制的信息。这项研究是对双重接种策略的首次评估，该策略有可能显着增强一级预防的实践。为了进一步增强该方法广泛传播的潜力，我们建议在预防试验的同时进行成本效益分析。