Network on Measurement of Biological Risk

生物风险测量网络

• 批准号: 9352757
• 负责人: EILEEN M CRIMMINS
• 金额: $ 27.64万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-15 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9352757
• 关键词: Address; Adoption; Affect; Age; Aging; Area; Behavioral; Biological; Biological Aging; Biological Assay; Biological Factors; Biological Markers; Biological Process; Biology; Cessation of life; Collection; Communities; Complex; Data; Data Collection; Databases; Development; Dimensions; Discipline; Disease; Disease Progression; Economic Factors; Economics; Educational workshop; Elderly; Environmental Risk Factor; Ethical Issues; Funding; Future; Genetic; Goals; Health; Health trends; Healthcare; Individual; Interdisciplinary Study; International; Knowledge; Laboratories; Laboratory Scientists; Link; Liquid substance; Manuals; Measurement; Measures; Methodology; Methods; Modeling; Monitor; Outcome; Participant; Physical Function; Physiological; Physiology; Pilot Projects; Population; Population Sciences; Population Study; Preparation; Probability; Protocols documentation; Psychological Factors; Publishing; Quality Control; Research; Research Personnel; Risk; Sampling; Scientist; Series; Subgroup; Surveys; Systems Biology; Time; Training; Treatment Effectiveness; Validity and Reliability; Work; analytical method; biological information processing; cognitive function; computerized data processing; design; disability; epidemiology study; genetic analysis; health difference; improved; interest; meetings; member; middle age; multidisciplinary; novel; population health; population survey; programs; psychologic; sample collection; social; study population; symposium; web site; working group

Project Summary/Abstract The goal of this project will be to further develop and maintain an interdisciplinary network of scientists dedicated to measuring biological risk for late life health outcomes in large representative samples of aging populations. Biological risk is defined by indictors of genetic and physiological state that increase the probability of disease, disability, loss of physical or cognitive functioning, or death. The network will focus on assessing, validating, and harmonizing biological risk measurement in studies of populations; expanding measures available for use in populations; and developing methodological approaches for including complex dimensions of health in analytic models. This project will build on the extensive progress made building an initial interdisciplinary research network (funded by NIA from 2009 to 2015). Activities of the network for the 2016-2021 period will include designing and carrying out a series of general and focused meetings including one annual meeting of the network members, regular meetings/conference calls with working subgroups, specialized workshops, working with individual studies to develop plans for data collection and processing, and supporting small pilot projects to harmonize and develop measurement. Dissemination of harmonizing information and harmonized data will be a major product of the network. The network will also disseminate protocols for collection methods, assay methods, quality control methods, harmonization methods, basic training on relevant topics of sample collection and preparation, and analytic methods. The network will promote valid interdisciplinary and international research on the associations of social, biological, economic, and psychological factors and the biological paths leading to health outcomes common in old age in large community and national population surveys. This growing area of scientific focus in the population sciences is at a crucial stage for further development from an organized network.

项目摘要/摘要 该项目的目标是进一步发展和维护科学家的跨学科网络 致力于衡量大型代表性衰老样本中生命健康结果的生物学风险 人群。生物学风险是由遗传和生理状态的检测器定义的 疾病，残疾，身体或认知功能丧失或死亡的概率。网络将重点关注 在人群研究中评估，验证和协调生物风险测量；扩展 可用于人口的措施；并开发包括复杂的方法学方法 分析模型中的健康维度。 该项目将建立在广泛的进展的基础上，使建立初始的跨学科研究网络 （2009年至2015年由NIA资助）。 2016 - 2021年期间网络的活动将包括设计 并举行一系列一般和专注的会议，包括一个网络年度会议 会员，与工作子组，专业研讨会的定期会议/电话会议，与 个人研究以制定数据收集和处理计划，并支持小型试点项目 协调和开发测量。传播协调信息和协调数据将是 网络的主要产品。该网络还将传播用于收集方法的协议，分析 方法，质量控制方法，协调方法，样本相关主题的基本培训 收集和准备和分析方法。 该网络将促进有关社会协会的有效跨学科和国际研究 生物学，经济和心理因素以及导致健康结果常见的生物学途径 大型社区和全国人口调查中的老年。这个科学重点的增长领域 人口科学处于有组织网络进一步发展的关键阶段。