Medical Marijuana, Emerging Adults & Community: Connecting Health and Policy

医用大麻，新兴成人

• 批准号: 8503943
• 负责人: Stephen E Lankenau
• 金额: $ 72.92万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8503943
• 关键词: Acquired Immunodeficiency Syndrome; Address; Adolescent; Adopted; Adult; Affect; Age; Alcohols; Benefits and Risks; Build-it; California; Chronic; Chronically Ill; Cities; Cohort Studies; Communities; Community Health; Data; Disease; District of Columbia; Drug Prescriptions; Drug usage; Funding; Goals; Guidelines; Health; Health Policy; Health behavior; Illicit Drugs; Individual; Knowledge; Lead; Left; Legal; Location; Los Angeles; Marijuana; Marijuana Smoking; Medical; Medicine; Mental Health; Methods; Mission; Modification; Natural History; Outcome; Patients; Pattern; Pharmaceutical Preparations; Physicians; Policies; Policy Maker; Psyche structure; Public Health; Qualitative Research; Recommendation; Recording of previous events; Recruitment Activity; Reporting; Research; Research Design; Research Methodology; Research Personnel; Role; Running; Scientific Advances and Accomplishments; Statutes and Laws; Terminally Ill; Testing; Time; United States National Institutes of Health; Work; aged; alcohol misuse; base; cohort; emerging adult; evidence base; experience; improved; innovation; malignant muscle neoplasm; marijuana user; member; physical conditioning; protective effect; psychologic; public health relevance; theories; young adult

DESCRIPTION (provided by applicant): A critical knowledge gap exists in the understanding of how medical marijuana (MM) policies have impacted emerging adults since MM became legal in California in 1996. It is unknown how MM has affected patterns of drug use, including alcohol, prescription, and illicit, among emerging adults. It is unknown how MM has impacted physical or psychological health among young medical marijuana patients (MMP). It is unknown how MM dispensaries influence health among young MMP, including the impact of closing MM dispensaries on access to MM. To address these gaps, a five-year project is being proposed in Los Angeles (LA) to study young MMP, young non-medical marijuana users (NMU), and MM dispensaries in natural settings using qualitative and quantitative methods. A long-term goal of the study is to recommend MM policies to local, state, and national officials that result in the most positive health outcomes for young adults and communities. The overall objective of this particular application is to determine the impact of LA's MM policies on emerging adults' physical and psychological health while understanding how medical marijuana dispensaries influence individual health. The central hypothesis guiding this study is that young MMP, as a result of access to MM and patient support offered by MM dispensaries, will report better physical and psychological health and less harmful patterns of drug use compared to NMU. This hypothesis is supported by preliminary data collected in LA on young MMP and NMU during a currently funded NIH study, which suggests important differences between these two groups as well as dissimilarities between young MMP and chronically ill, older MMP. The rationale for the proposed research is that young MMP and NMU will be impacted by MM policy longer than other adult cohorts with unknown consequences, while the diverse setting of LA - with its large number of MM dispensaries - is an optimal location to study this cohort. Guided by preliminary data, this hypothesis will be tested by pursuing three specific aims: 1) Determine the basis for MMP status and its impact on trajectories of physical and psychological health among emerging adults. 2) Determine the impact of MMP status on patterns of drug use among emerging adults, including intensity of marijuana use and misuse of alcohol, prescription drugs, and illicit drugs. 3) Describe the natural history of marijuana use in Los Angeles among MMP and NMU. The approach is innovative because it focuses on a critical cohort of young adults, it builds upon findings and theoretical perspectives from the field of non- medical marijuana research, and it integrates quantitative and qualitative research methodologies into a longitudinal research design. The proposed research is significant since study data can provide evidence- based rationales for modifying patient health behaviors, physician guidelines, and city ordinances. Ultimately, determining the impact of medical marijuana on the health of emerging adults and communities in LA has the potential to inform medical marijuana policy at the local, state, and national levels.

描述（由申请人提供）：自 1996 年医用大麻 (MM) 在加利福尼亚州合法以来，对于医用大麻 (MM) 政策如何影响新兴成年人的理解存在着关键的知识差距。目前尚不清楚 MM 如何影响包括酒精在内的药物使用模式、处方药和非法药物，在新兴成年人中。目前尚不清楚 MM 如何影响年轻医用大麻患者 (MMP) 的身体或心理健康。目前尚不清楚 MM 药房如何影响年轻 MMP 的健康，包括关闭 MM 药房对获得 MM 的影响。为了解决这些差距，洛杉矶 (LA) 提出了一个为期五年的项目，利用定性和定量方法研究自然环境中的年轻 MMP、年轻非医用大麻使用者 (NMU) 和 MM 药房。该研究的长期目标是向地方、州和国家官员推荐 MM 政策，为年轻人和社区带来最积极的健康结果。此特定应用程序的总体目标是确定洛杉矶的 MM 政策对新兴成年人身心健康的影响，同时了解医用大麻药房如何影响个人健康。指导这项研究的中心假设是，与 NMU 相比，年轻的 MMP 由于获得 MM 和 MM 药房提供的患者支持，将报告更好的身心健康以及更少的有害药物使用模式。这一假设得到了在目前资助的 NIH 研究期间在洛杉矶收集的关于年轻 MMP 和 NMU 的初步数据的支持，该数据表明这两组之间存在重要差异，以及年轻 MMP 和慢性病、老年 MMP 之间的差异。拟议研究的基本原理是，年轻的 MMP 和 NMU 受到 MM 政策影响的时间将比其他成年群体更长，后果未知，而洛杉矶的多样化环境（拥有大量 MM 药房）是研究该群体的最佳地点。在初步数据的指导下，该假设将通过三个具体目标进行检验：1）确定 MMP 状态的基础及其对新兴成年人身心健康轨迹的影响。 2) 确定 MMP 状态对新生成年人吸毒模式的影响，包括吸食大麻和滥用酒精、处方药和非法药物的强度。 3) 描述洛杉矶 MMP 和 NMU 吸食大麻的自然历史。该方法具有创新性，因为它关注的是关键的年轻人群体，它建立在非医用大麻研究领域的发现和理论观点之上，并将定量和定性研究方法整合到纵向研究设计中。拟议的研究意义重大，因为研究数据可以为改变患者健康行为、医生指南和城市法令提供基于证据的基本原理。最终，确定医用大麻对洛杉矶新兴成年人和社区健康的影响有可能为地方、州和国家各级的医用大麻政策提供信息。