FDA FERN Microbiology and Chemistry Cooperative Agreement Programs: Enhanced Food Safety

FDA FERN 微生物学和化学合作协议计划：增强食品安全

• 批准号: 9336709
• 负责人: Eric Petty
• 金额: $ 55万
• 依托单位: COLORADO STATE DEPT/PUB HLTH & ENVIRONMT
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9336709
• 关键词: FDA; FERN; Microbiology; Chemistry; Cooperative

Co-Principal Investigators: Eric Petty and Hugh Maguire, PhD Project Summary / Abstract CCAP: Enhanced Food Safety and Food Defense Capacity and Capability Utilizing existing chemistry equipment platforms, methods and personnel the Colorado Department of Public Health and Environment Laboratory will expand food defense and food safety capacity and expertise to advance an integrated food safety system. As a compliment to FERN National Program Office (NPO) required emergency surge capacity or other assignments, routine food surveillance will be conducted. Weekly sampling of a variety of food matrices will rotate to cover meats, fruits and vegetables, baby foods, beverages and ready to eat foods. Meats and avocados currently collected for microbiological analyses as part of the CDC/FDA NARMS program and the FDA High Volume Surveillance Activation Project will also be incorporated into the routine analyses of approximately 40 samples per month. New and unique food matrices encountered may serve as matrix extension projects. Through continual weekly usage of all the various platforms and methods organizational emergency preparedness and analyst competence will be optimized. Increasing staff expertise in LC- MS/MS, expanding the number of staff trained in sample extraction and the duplication of instrumental expertise are areas of focus. Funds provided to our newly created laboratory Quality Assurance Unit will aid in our efforts toward ISO/IEC 17025 accreditation. Direct and frequent communication with the FERN (NPO) will be maintained through participation in conference calls, attendance at National FERN meetings, electronic reporting of status updates and data transmission. A commitment to overall FERN Program improvement will be demonstrated through active involvement in assigned projects, proficiency tests, method validations and intra-laboratory planned research activities. MCAP: Enhanced Food Safety and Security Testing Program As a direct result of the funding provided throughout multiple award years to the MCAP at the Colorado laboratory solid foundations were established for enhanced microbiological and chemical testing. Key personnel will continue participation in the program assignment of analyzing avocado samples for the presence of Salmonella and Listeria monocytogenes. Staff will continue to accept this product from domestic sources in support of the program. An early assessment of this program demonstrates a high level of success. Current plans include the continuation of this assignment and will add equivalent testing of imported product as assigned. Two new projects will be undertaken during the first year of the continuation award to enhance existing capabilities. A multicenter validation study that will be completed under current funding will be implemented to support current assignments and provide rapid and sensitive detection capabilities. Establishment of new detection methods will be combined with existing standard methods and applied to additional targets as defined by program directives. Examples currently under consideration for these matrix extensions are cucumbers and hot peppers. Use of these designated protocols will provide consistency of analytical findings as demonstrated through the positive outcomes of both proficiency tests and live assignments supported by the program to date. Colorado laboratory staff will engage in all activities proposed or assigned by the national program office in support of enhanced food safety. Ongoing support through this continuation award will provide greater return on investment as the Colorado laboratory operates as an extension of the national program for food safety.

联合调查人员：埃里克·佩蒂（Eric Petty）和休·马奎尔（Hugh Maguire），博士 项目摘要 /摘要 CCAP：增强食品安全和食品防御能力和能力 利用现有的化学设备平台，方法和人员 公共卫生和环境实验室将扩大食品防御和食品安全 能够推进综合食品安全系统的能力和专业知识。以对蕨国的称赞 计划办公室（NPO）需要紧急激增能力或其他任务，常规食品 将进行监视。每周对各种食物矩阵的抽样将旋转以覆盖肉， 水果和蔬菜，婴儿食品，饮料和准备食用食物。肉类和鳄梨 作为CDC/FDA NARMS计划的一部分和FDA高量 监视激活项目也将纳入约40个常规分析中 每月样本。遇到的新的和独特的食物矩阵可以用作矩阵扩展 项目。通过不断每周使用所有各种平台和方法组织 应急准备和分析师能力将得到优化。提高LC-的员工专业知识 - MS/MS，扩大了在样品提取方面接受培训的员工数量和仪器的重复 专业知识是重点领域。提供给我们新创建的实验室质量保证单元的资金将 帮助我们为ISO/IEC 17025认证的努力。直接频繁地与 Fern（NPO）将通过参加电话会议，出席国家蕨 会议，状态更新的电子报告和数据传输。对整体蕨类的承诺 计划改进将通过积极参与分配的项目来证明 熟练测试，方法验证和实验室内计划的研究活动。 MCAP：增强的食品安全和保障测试计划 这是由在MCAP多多年颁发的多年奖励的直接结果 建立了科罗拉多实验室固体基础，以增强微生物学和化学 测试。关键人员将继续参与分析鳄梨的计划分配 样品，有沙门氏菌和单核细胞增生李斯特菌的存在。工作人员将继续接受 来自国内来源的产品以支持该计划。对该计划的早期评估 证明了很高的​​成功。当前的计划包括该任务的延续，并将 添加分配的导入产品的等效测试。将在 延续奖的第一年，以增强现有功能。一项多中心验证研究 将根据当前资金完成，以支持当前作业和 提供快速，敏感的检测功能。建立新的检测方法将是 与现有的标准方法结合使用，并应用于程序定义的其他目标 指令。这些矩阵扩展程序目前正在考虑的示例是黄瓜和热 胡椒。这些指定协议的使用将提供分析结果的一致性 通过支持的两种能力测试和实时作业的积极结果证明 迄今为止的程序。科罗拉多州实验室工作人员将参与所有提议或分配的活动 国家计划办公室支持增强食品安全。持续的支持 由于科罗拉多州实验室作为一个 扩展国家食品安全计划。