UNZA-VANDERBILT PARTNERSHIP FOR HIV-NUTRITION RESEARCH TRAINING (UVP)

UNZA-范德比尔特艾滋病毒营养研究培训合作伙伴关系 (UVP)

• 批准号: 9313359
• 负责人: DOUGLAS CORBETT HEIMBURGER
• 金额: $ 30.2万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-15 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9313359
• 关键词: Affect; African; Aging; Award; Cardiovascular system; Caring; Chronic; Clinical Nutrition; Clinical Trials; Collaborations; Comorbidity; Consultations; Country; Databases; Doctor of Philosophy; Educational workshop; Epidemiology; Extramural Activities; Faculty; Follow-Up Studies; Funding; Future; Gastrointestinal tract structure; Grant; HIV; Institutes; Kidney; Leadership; Life Style; Measures; Mentors; Mentorship; Metabolic; Nervous system structure; Nutritional; Nutritional Study; Output; Pathogenicity; Process; Program Evaluation; Research; Research Personnel; Research Training; Resources; SERPINI2 gene; Specimen; Teacher Professional Development; Teaching Hospitals; Training; Training Support; Training and Education; Universities; Zambia; antiretroviral therapy; base; career development; course development; global health; innovation; instructor; low income country; medical schools; member; multidisciplinary; nutrition; programs; sabbatical; skills; success; therapy outcome

 DESCRIPTION (provided by applicant): The UNZA-Vanderbilt Training Partnership for HIV-Nutrition-Metabolic Research (UVP) continues a longstanding training collaboration of the University of Zambia School of Medicine/University Teaching Hospital (UNZA/UTH) and Vanderbilt University (VU) and its Institute for Global Health (VIGH). With PEPFAR's successes turning HIV into a chronic condition, many Africans are living full lives with HIV, but they are facing non-communicable diseases that come with lifelong antiretroviral therapy (ART), lifestyle changes accompany- ing the epidemiologic transition, and aging. Nutritional factors are central to many of these, especially in low- income countries, affecting pathogenic processes in the gastrointestinal tract, kidneys, nervous system, and cardiovascular system. UNZA-VIGH collaborations have discovered multiple nutritional influences on ART outcomes. A recently completed large-scale HIV-nutrition clinical trial (NUSTART) has built large specimen and data repositories that are available for analyses and long-term follow-up studies. UNZA has identified PhD training as crucial for advancing its institutional research capacity and academic leadership. UVP will support this by training UNZA PhD-level HIV research leaders in nutritionally- and metabolically related complications and comorbidities of HIV, while expanding UNZA/UTH's research training and investigative capacities. UVP will provide long-term research training for advanced UNZA trainees and junior faculty members, leading to 11 "sandwich" PhD degrees awarded by UNZA and undergirded by Vanderbilt didactic courses, research mentorship, and institutional resources. It will support innovative multidisciplinary mentored dissertation research focused on the key metabolic and nutritional challenges in long-term HIV care. The UVP proposal is distinguished by a 17-year AITRP partnership that has enabled 41 Zambians to obtain advanced degrees (mainly Master's) and has substantially facilitated many US grant-funded education and training efforts described within (AITRP, MEPI, ZEPACT, FICRS-F, Fogarty GHF). UVP will enhance the UNZA PhD Program by conducting in-country consultations, skill-building short courses, and faculty development workshops to strengthen PhD mentoring standards and assess measureable milestones. It will provide career development opportunities for research-focused UNZA faculty members via 4-month VU-based postdoctoral sabbaticals, to expand research collaborations between UNZA and VU investigators and to attract extramural research funding. We will document the program's long-term success by tracking major trainee outputs; providing ongoing skill-building opportunities for our AITRP alumni; conducting regular program evaluations; and engaging our AITRP alumni as active in-country instructors in ongoing Zam- bia-based trainings. UVP will strengthen UNZA's capacity to train future researchers, attract extramural research funding, and generate high-impact research outputs in a vital HIV research arena. Sustainabil- ity will be maximized by mentoring future mentors within all UVP activities.

 描述（由应用程序提供）：HIV-NUTRITION-METEBOLIC研究（UVP）的UNZA-Vandanderbilt培训伙伴关系持续了赞比亚大学医学/大学教学医院（UNZA/UTH）和Vanderbilt University（VU）及其全球健康研究所（VIGH）的长期培训合作。随着PEPFAR的成功将艾滋病毒变成慢性病，许多非洲人正以艾滋病毒过着充实的生活，但他们面临着终生抗逆转录病毒疗法（ART）带来的非通信疾病，生活方式的改变发生在流行病学过渡和衰老。营养因素对其中许多是核心，尤其是在低收入国家，影响胃肠道，肾脏，神经系统和心血管系统的致病过程。 Unza-Vigh的合作发现了对艺术成果的多种营养影响。最近完成的大规模HIV-NUTRITION临床试验（NUSTART）建造了大型标本和数据存储库，可用于分析和长期随访研究。 UNZA已将博士培训确定为提高其机构研究能力和学术领导力至关重要。 UVP将通过培训UNZA PHD级HIV研究负责人来支持这一点，以了解艾滋病毒的营养和代谢相关并发症和合并症，同时扩大UNZA/UTH的研究培训和调查能力。 UVP将为高级UNZA学员和初级教职员工提供长期的研究培训，从而将UNZA授予11个“三明治”博士学位，并由Vanderbilt Didactic课程，研究指导和机构资源授予。它将支持创新的多学科指导学论文研究，重点是长期艾滋病毒护理中的关键代谢和营养挑战。 UVP提案以17年的AITRP合作伙伴关系为特色，该伙伴关系使41个赞比亚人获得了高级学位（主要是硕士学位），并基本上支持了许多美国赠款资助的教育和培训工作（AITRP，MEPI，Zepact，Zepact，fiCRS，FICRS，FICRS-F，Fogarty GHF）。 UVP将通过进行国内咨询，技能培养简短的课程和教师发展研讨会来增强UNZA博士学位计划，以增强博士学位心理标准并评估可衡量的里程碑。它将通过基于4个月的VU博士后休假为以研究为中心的UNZA教职员工提供职业发展机会，以扩大UNZA和VU研究人员之间的研究合作，并吸引壁外研究资金。我们将通过跟踪主要学员的产出来记录该计划的长期成功；为我们的AITRP校友提供持续的技能建设机会；进行定期计划评估；并让我们的AITRP校友成为正在进行的基于ZAMBIA的培训中的积极的国内讲师。 UVP将增强UNZA培训未来研究人员，吸引壁外研究资金并在重要的HIV研究领域产生高影响力的研究成果的能力。可持续性 - 可以通过所有UVP活动中的心理未来精神来最大化。