Loma Linda University Center for Health Disparities Research

洛马琳达大学健康差异研究中心

基本信息

批准号：
9003807
负责人：
Marino De Leon
金额：
$ 118.96万
依托单位：
LOMA LINDA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-07-01 至 2020-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9003807
关键词：
Address African American Award Bachelor&apos s Degree Biological Biomedical Research California Cities Communities Community Health Education Community Networks Data Development Diabetes Mellitus Discipline Disease Education Education and Outreach Enrollment Ensure Fostering Generations Genes Goals Graduation Rates Grant Hispanics Individual Inequality Instruction Intervention Latino Lead Light Malignant neoplasm of prostate Mediator of activation protein Medical Students Mexican Americans Mission Mississippi Modeling National Center on Minority Health and Health Disparities Non-Insulin-Dependent Diabetes Mellitus Obesity Outcome Policies Population Poverty Prevention education Prostate Recruitment Activity Reporting Research Research Infrastructure Research Personnel Research Training Resources Science, Technology, Engineering and Mathematics Shock Students Training Training and Education Training and Infrastructure Translations Underrepresented Minority Underserved Population Universities Woman Work base cancer type career college design disorder prevention education research health disparity high school improved innovation malignant breast neoplasm medically underserved population men minority health outreach population based prevent programs public health relevance retention rate social success summer research triple-negative invasive breast carcinoma underrepresented minority student university student volunteer

项目摘要

DESCRIPTION (provided by applicant): The Loma Linda University Center for Health Disparities Research (LLU CHDR) was established by an EXPORT award from the NCMHD to develop new infrastructure for research in health disparities at LLU and the Inland Empire (IE) region of Southern California. The overall goal of this competitive renewal application is to support a successful enterprise that is already addressing health disparities in the IE. The four objectives of this application are: Objective 1: To enhance the research and administrative infrastructure of LLU to conduct competitive and sustainable research, training, education and outreach in health disparities. This objective will ensure having an efficient administrative infrastructure to support the center. Objective 2 is to build a successful enterprise in health disparities research leading to translational discoveries to reduce the burden of breast cancer, prostate cancer, and type 2 diabetes disparities. Innovative approaches to study gene-environmental interactions in type 2 diabetes in Mexican Americans, immunoseroproteomics profiling in African American men with prostate cancer, and triple negative breast cancer chemoreslstance in African American women, will lead the center to address these killer diseases that are disproportionately impacting underserved communities. Objective 3 is to sustain a comprehensive and robust pipeline of health disparities researchers from underrepresented and medically underserved populations. The center has identified a pool of hundreds of students from health disparities populations that have been participating in this successful program. Objective 4 is to engage with an established network of CBOs and LLU partnerships in addressing the problems of health disparities and to facilitate the translation of advances in breast cancer, prostate cancer and Type 2 diabetes to underserved communities. Fulfilling this objective will result in an army of trained and LLU certified "Promotores" engaged in prevention education program to reduce the burden of health disparities diseases in this underserved region of California. Accomplishment of these objectives will make the LLU CHDR/CHDMM an established resource for excellence in research, training and successful partnership. .

描述（由申请人提供）：洛马琳达大学健康差异研究中心 (LLU CHDR) 是根据 NCMHD 的出口奖建立的，旨在为 LLU 和南部内陆帝国 (IE) 地区的健康差异研究开发新的基础设施加利福尼亚州。此竞争性续订应用程序的总体目标是支持已经解决 IE 中健康差异问题的成功企业。该应用程序的四个目标是：目标 1：加强 LLU 的研究和管理基础设施，以在健康差异方面开展有竞争力和可持续的研究、培训、教育和推广。这一目标将确保拥有高效的行政基础设施来支持该中心。目标 2 是在健康差异研究领域建立一个成功的企业，从而产生转化性发现，以减轻乳腺癌、前列腺癌和 2 型糖尿病差异的负担。研究墨西哥裔美国人 2 型糖尿病的基因-环境相互作用、非裔美国男性前列腺癌的免疫血清蛋白质组学分析以及非裔美国女性的三阴性乳腺癌化学耐药性的创新方法，将引导该中心解决这些影响不成比例的致命疾病服务不足的社区。目标 3 是维持来自代表性不足和医疗服务不足人群的健康差异研究人员的全面和强大的渠道。该中心已经确定了数百名来自健康差异人群的学生参与了这一成功的项目。目标 4 是与已建立的 CBO 和 LLU 伙伴关系网络合作，解决健康差距问题，并促进将乳腺癌、前列腺癌和 2 型糖尿病方面的进展转化为服务不足的社区。实现这一目标将导致一支训练有素且获得 LLU 认证的“Promotores”大军参与预防教育计划，以减轻加州这一服务欠缺地区的健康差异疾病负担。这些目标的实现将使 LLU CHDR/CHDMM 成为卓越研究、培训和成功合作伙伴关系的既定资源。。

项目成果

期刊论文数量（30）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer.

DOI：
10.18632/oncotarget.9869
发表时间：
2016-07-12
期刊：
Oncotarget
影响因子：
0
作者：
Li J;Dai L;Lei N;Xing M;Li P;Luo C;Casiano CA;Zhang JY
通讯作者：
Zhang JY

A Qualitative Study on the Perspectives of Latinas Enrolled in a Diabetes Prevention Program: Is the Cost of Prevention Too High?

DOI：
10.1177/2150132720945423
发表时间：
2020-01
期刊：
Journal of primary care & community health
影响因子：
3.6
作者：
Joachim-Célestin M;Gamboa-Maldonado T;Dos Santos H;Montgomery SB
通讯作者：
Montgomery SB

Preferential autoimmune response in prostate cancer to cyclin B1 in a panel of tumor-associated antigens.

DOI：
10.1155/2014/827827
发表时间：
2014
期刊：
Journal of immunology research
影响因子：
4.1
作者：
Dai L;Li J;Ortega R;Qian W;Casiano CA;Zhang JY
通讯作者：
Zhang JY

Middle school cycling program is associated with improved mental health and wellbeing in adolescents during COVID-19.

DOI：
10.3389/fspor.2023.1255514
发表时间：
2023
期刊：
FRONTIERS IN SPORTS AND ACTIVE LIVING
影响因子：
2.7
作者：
Dementyev, Fletcher;Fish, Brian;Opoku, Nana Yaa Sakyi;Tesfaye, Lydia;Chan, Jason;Ortiz, Larry;Montgomery, Susanne B.;Walker, Esther J.;Wilson, Sean M.
通讯作者：
Wilson, Sean M.

Are perceptions of community safety associated with respiratory illness among a low-income, minority adult population?