Graduate Training in Integrative Physiology

综合生理学研究生培训

• 批准号: 9280078
• 负责人: Bret N Smith
• 金额: $ 18.52万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9280078
• 关键词: Physiology; Training

Project Summary This is a resubmission of a T32 application requesting funding for a new Graduate Training in Integrative Physiology training program for 4 predoctoral fellows/year. Training of the predoctoral fellows will be carried out by participating faculty with proven track records of cross-disciplinary research on a variety of health issues. The overall goal of the proposed program is to provide broad-based training in modern research concepts required to study quantitatively the nature of physiological processes in both healthy and disease states, which is necessary to drive discovery of new therapeutic strategies for treating the underlying causes of diseases affecting multiple organs and systems. The primary objectives are to: 1) provide a comprehensive, quantitative training program for early stage trainees in physiology with a particular emphasis on cardiovascular, aging, neurophysiology, and muscle biology research; and 2) promote interdisciplinary learning teams involving basic scientists, clinicians and trainees to foster rigorous innovative translational science. Predoctoral fellows will be trained in the practical issues involved in the design and conduct of basic and translational research to enhance their future ability to make therapeutic discoveries for diseases of broad etiology as independent investigators. To accomplish this, the predoctoral fellows will engage in cutting-edge, quantitative, physiologically-based research. In addition to specialized didactic coursework, they will participate in a comprehensive Experimental Design Workshop and attend weekly seminars and grand rounds presentations focused on cardiovascular, aging-related, neurological, or musculoskeletal diseases. Although most of the trainees are anticipated to pursue careers in laboratory-based discovery research, they will also receive training in conveying knowledge to other scientists through grant-writing and communications skills workshops. The combination of these training avenues will provide skills to disseminate their knowledge and provide them with an understanding of how to design and conduct research in a manner that will enable the translation of promising therapies into the clinic.

项目摘要 这是对T32申请的重新提交，该申请要求资助新的综合研究生培训 4年/年的4个专家培训计划。将进行培训前研究员的培训 通过参加跨学科研究的经过验证的有关各种健康的跨学科研究的记录 问题。该计划的总体目标是在现代研究中提供基于广泛的培训 定量研究健康和疾病中生理过程的性质所需的概念 国家，这是推动发现新的治疗策略以治疗基本原因的必要条件 影响多个器官和系统的疾病。主要目标是：1）提供全面的， 生理学早期学员的定量培训计划，特别强调 心血管，衰老，神经生理学和肌肉生物学研究； 2）促进跨学科学习 涉及基础科学家，临床医生和学员的团队，以培养严格的创新转化科学。 托管前研究员将接受有关基本设计和行为涉及的实际问题的培训 转化研究，以增强他们未来对广泛疾病的治疗发现的能力 病因作为独立研究者。为了实现这一目标，摄影前研究员将参与尖端， 定量，基于生理的研究。除了专业的教学课程外，他们还将参加 在全面的实验设计研讨会中，参加每周一次的研讨会和大回合 介绍的重点是心血管，与衰老有关的，神经系统或肌肉骨骼疾病。虽然 预计大多数学员将从事基于实验室的发现研究中的职业，他们也将 通过赠款和沟通技巧将知识传达给其他科学家的培训 讲习班。这些培训途径的结合将提供传播其知识和的技能 向他们提供对如何设计和进行研究的理解 将有希望的疗法转化为诊所。