UCLA SPORE in Prostate Cancer

UCLA SPORE 在前列腺癌中的应用

基本信息

批准号：
9271057
负责人：
ROBERT E REITER
金额：
$ 10万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
起止时间：
2002-09-15 至 2016-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9271057
关键词：
Anatomy Androgen Receptor Area Attention Bioinformatics Biometry Cancer Patient Castration Cell Nucleus Chemistry Clinic Clinical Development Diagnosis Diet Modification Discipline Disease Engineering Environment FDA approved Faculty Fat-Restricted Diet Fostering Funding Goals Human Image Institutes Institution Interdisciplinary Study Laboratory Research Malignant neoplasm of pancreas Malignant neoplasm of prostate Measurable Molecular Morbidity - disease rate Nanotechnology National Cancer Institute Neoplasm Circulating Cells Neoplasm Metastasis Omega-3 Fatty Acids Outcome PTEN gene Pathology Pathway interactions Primary Prevention Prostate Radiology Specialty Research Research Infrastructure Research Personnel Research Support Resistance Scientist Secondary Prevention Seminal Services Signal Pathway Signal Transduction Sister Specimen Staging Talents Technology Translational Research Translations antibody engineering anticancer research base biomarker-driven cancer cell cancer stem cell career development clinical application clinical practice data management design human capital improved innovation men mortality nanosystems new technology novel outcome forecast pre-clinical prevent programs prostate stem cell antigen stem cell biology therapy resistant tumor microenvironment

项目摘要

The UCLA Prostate Cancer SPORE is a multidisciplinary and translational research program focused on the development of new and innovative approaches for improving the diagnosis, prognosis, and treatment of prostate cancer patients. Initially built around a small nucleus of basic and clinical scientists, the program has expanded around campus to bring diverse talents from disciplines as varied as Chemistry, Nanotechnology, Stem Cell Biology, Pathology and Radiology to focus on the prostate cancer problem. This campus-wide (including UCLA affiliated-institutions) enterprise has led to significant discoveries with potential major impact on men with prostate cancer. The overall goal of this competitive renewal application is to continue to apply the diversity of talent on the UCLA campus and its sister institutions to the critical and evolving translational challenges in the fied of prostate cancer. To achieve the long-term objectives and goals of our program, the Specific Aims of the UCLA SPORE in Prostate Cancer are: 1. Perform high-impact translational research focused on some of the major challenges in the field of prostate cancer by: 2. Provide organizational infrastructure and novel technologies designed specifically to support the translational research objectives of the SPORE: 3. Develop new prostate cancer researchers and research areas to advance translational research in prostate cancer

UCLA前列腺癌孢子是一项多学科和转化研究计划，旨在开发新的和创新的方法，用于改善前列腺癌患者的诊断，预后和治疗。该计划最初建立在基本和临床科学家的小核中，在校园周围扩大了范围，从而从化学，纳米技术，干细胞生物学，病理学和放射学等学科中带来了多样化的人才，以关注前列腺癌问题。该企业在整个校园（包括加州大学洛杉矶分校的附属机构）企业中引起了重大发现，对前列腺癌男性有重大影响。这种竞争性更新应用的总体目标是继续在UCLA上运用人才的多样性校园及其姊妹机构在前列腺癌的批评和不断发展的转化挑战中。为了实现我们计划的长期目标和目标，UCLA孢子在前列腺癌中的具体目标是： 1。进行高影响的翻译研究，重点是前列腺癌领域的一些主要挑战： 2.提供专门旨在支持孢子的翻译研究目标的组织基础设施和新技术： 3。开发新的前列腺癌研究人员和研究领域，以推进前列腺癌的转化研究