Neurobehavior, Neuropathology, and Risk Factors in Alzheimer's Disease

阿尔茨海默病的神经行为、神经病理学和危险因素

• 批准号: 9265401
• 负责人: ELAINE R. PESKIND
• 金额: $ 33.25万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9265401
• 关键词: Alzheimer' s Disease; Risk Factors; neurobehavior; neuropathology

 DESCRIPTION (provided by applicant): We are applying for funding of our Alzheimer's disease Training Program (ADTP), "Neurobehavior, Neuropathology, and Risk Factors in Alzheimer's Disease." Our program focuses on translational research in Alzheimer's disease (AD) and related dementias. The objective of our research training program is to provide interdisciplinary training for basic science, clinical, and translational researchers so that they ill be able to advance clinical hypotheses about the etiology, pathophysiology, and treatment of AD and related disorders. Our training program is the only formal program at the University of Washington focused on training investigators to carry out basic, clinical, and translational research in AD and related neurodegenerative dementing disorders. Our program is supported by the rich and interactive research environment of the University of Washington and Veterans Affairs Puget Sound Health Care System, where a critical mass of faculty conduct research across the spectrum of AD and related dementias. The program is requesting training positions for 5 postdoctoral trainees. For postdoctoral trainees our goal is to have ~40% clinical (MD, MD/PhD, or PhD in Clinical Psychology) and ~60% research (PhD) postdoctoral fellows. Incoming MD candidates are expected to have completed a residency, usually in psychiatry, neurology, neuropathology, radiology, internal medicine, or geriatric medicine. Postdoctoral PhD candidates from come a broad range of disciplines, including clinical psychology, neuropsychology, biochemistry, genetics, neurobiology, and pharmacology. Basic science trainees typically join the program during their 1st year of postgraduate training and usually remain for three years. MD and clinician PhD fellows are expected to remain for a two year period, and will be strongly encouraged to remain for a third. We are also requesting training positions for 4 predoctoral candidates. Predoctoral trainees will be recruited from the following UW PhD programs: Genome Sciences, Molecular Basis of Disease, Molecular and Cellular Biology, Neurobiology and Behavior, and Pharmacology, and will join the ADTP program in their 2nd or 3rd year of graduate training. Special recruitment efforts will be made to include underserved minority trainees.

 描述（由适用提供）：我们正在申请对阿尔茨海默氏病训练计划（ADTP）的资助，“神经行为，神经病理学和阿尔茨海默氏病风险因素”。我们的计划着重于阿尔茨海默氏病（AD）和相关痴呆症的翻译研究。我们的研究培训计划的目的是为基础科学，临床和翻译研究人员提供跨学科培训，以便他们能够提高有关病因，病理生理学以及AD及相关疾病的治疗的临床假设。我们的培训计划是华盛顿大学唯一的正式计划，致力于培训调查人员在AD和相关神经退行性痴呆症中进行基本，临床和翻译研究。我们的计划得到了华盛顿大学和退伍军人事务普吉特海湾医疗保健系统的丰富而互动研究的环境的支持，那里的批判性教师在AD和相关痴呆症的范围内进行了研究。该计划要求为5位博士后学员培训职位。对于博士后学员，我们的目标是在临床心理学中拥有约40％的临床（MD，MD/PHD或博士学位）和〜60％的研究（PHD）博士后研究员。预计传入的医学博士候选人将在精神病学，神经病学，神经病理学，放射学，内科医学或老年医学上完成住所。来自广泛学科的博士后博士候选人，包括临床心理学，神经心理学，生物化学，遗传学，神经生物学和药理学。基础科学学员通常在研究生的第一年培训中加入该计划，通常要持续三年。医学博士和临床博士学位研究员预计将保留两年，我们还要求为4名候选人候选人培训职位。将从以下UW博士学位课程中招募专业学员：基因组科学，疾病的分子基础，分子和细胞生物学，神经生物学和行为以及药理学，并将在其研究生培训的第二或第三年中加入ADTP计划。特别的招聘工作将包括服务不足的少数民族学员。