Adaptation and Pilot Testing of a Mindfulness-Based Behavioral Intervention for Older Women with Low Sexual Desire

针对性欲低下的老年女性的基于正念的行为干预的适应和试点测试

基本信息

批准号：
9314045
负责人：
Holly Nicole Thomas
金额：
$ 18.77万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-15 至 2022-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9314045
关键词：
Academic Medical Centers Address Adult Adverse effects Affect Age Aging Arousal Attention Award Awareness Behavior Therapy Behavioral trial Caring Chronic low back pain Clinical Research Cognition Cohort Effect Control Groups Data Development Diabetes Mellitus Dryness Educational workshop Elderly Enrollment Ensure Female Focus Groups Funding Goals Health Individual Intervention Interview Investigation K-Series Research Career Programs Life Cycle Stages Longevity Manuals Measures Medical Mental Depression Mental Health Mentors Mentorship Mission Monitor Musculoskeletal Pain Outcome Pain Disorder Participant Pharmaceutical Preparations Pharmacologic Substance Phase Physicians Physiological Plant Roots Population Prevalence Provider Public Health Qualitative Research Quality of life Randomized Randomized Clinical Trials Randomized Controlled Trials Recording of previous events Reporting Research Research Methodology Research Personnel Research Support Research Training Resources Role Scientist Sex Behavior Sex Functioning Sexual Dysfunction Sexual Health Sexual Partners Societies Stimulus Surveys Testing Thinking Time Training Treatment Efficacy United States National Institutes of Health Universities Vagina Woman Women&apos s Health Work aged base behavioral clinical trial bodily sensation career clinical efficacy design effective therapy efficacy testing efficacy trial experience follow-up group intervention improved meetings mindfulness mindfulness intervention mindfulness meditation negative affect older women patient oriented physical conditioning prevent programs psychologic satisfaction sex sexually active skills social young woman

项目摘要

PROJECT SUMMARY Candidate and career goals: My overall career goal is to become an independent physician-scientist conducting interdisciplinary, patient-centered clinical research to improve sexual function in aging women. This K23 Career Development Award will provide me with the additional experience and skills to reach this goal. I have a long-standing passion for women's health and interdisciplinary investigation, and additional training in behavioral clinical trials, the psychological and physiologic aspects of female sexual function, and advanced research methods in geriatric women's health will ensure my successful transition to independence. Training will include didactic coursework, national workshops, society meetings, one-on-one mentored tutorials, and participation in seminars. My interdisciplinary mentoring team includes Dr. Thurston (primary mentor, women's health and aging), Dr. Resnick (geriatric women's health, behavioral trials), Dr. Borrero (qualitative research, career mentorship), and Dr. Brotto (mindfulness, sexual function). In addition, I will be supported by the University of Pittsburgh, a major academic medical center with a long history of high quality research. Currently ranked 5th in the nation in NIH funding, the University comprises a wealth of research and training resources to enable me to meet my goals. Research plan: Almost half of U.S. women experience sexual problems, which have significant negative impacts on physical and mental health. Low sexual desire is the most common sexual problem, particularly among women 50 and older, but there are few treatment options available. Treatments that can address both physical and psychological aspects of sexual dysfunction may be more effective than medications. Mindfulness is a practice that emphasizes in-the-moment focus and non-judgmental bodily awareness. A group-based behavioral intervention rooted in mindfulness has shown early promise in small trials, but only among younger women. The overall objective of this study is to adapt and pilot test a mindfulness intervention in women 50 and older with low sexual desire. In phase one, data from qualitative research among older women will be used by the primary investigator and a stakeholder advisory to adapt an existing mindfulness intervention. In phase 2, fifty women will be randomized to the adapted intervention or an educational control group on general health and aging. Feasibility and acceptability of the intervention, as well as changes sexual desire, function, and satisfaction, will be assessed. Findings from this study will be used to design a larger efficacy trial to test the adapted intervention. The proposed award is consistent with the mission of the NIA to support research using “integrative approaches to the study of social, psychological, and physiological influences on health and well- being over the life course.” Developing effective treatments for women's sexual problems will not only improve women's sex lives. It will address a significant public health need by allowing adults to maintain high quality of life and essential social relationships with aging.

项目摘要候选人和职业目标：我的整体职业目标是成为独立的医师科学家进行跨学科的，以患者为中心的临床研究，以改善衰老女性的性功能。 K23职业发展奖将为我提供实现这一目标的其他经验和技能。对妇女健康和跨学科调查有长期的热情，并对行为临床试验，女性性功能的心理和生理方面以及先进的老年妇女健康的研究方法可确保我成功过渡到独立。将包括教学课程，国家研讨会，社会会议，一对一的指导教程，以及参加研讨会。我的跨学科指导团队包括瑟斯顿博士健康与衰老），Resnick博士（老年妇女健康，行为试验），Borrero博士（定性研究，职业指导）和Brotto博士（正念，性功能）。目前。该大学在NIH资助的国家旅馆中排名，包括大量的研究和培训资源使我能够实现自己的目标。研究计划：几乎一半的美国妇女遇到了性问题，而性问题显着对身体健康的影响是最常见的性问题在50岁及以上的女性中性功能障碍的身体和心理方面可能比药物更有效。是一种强调自己的焦点和非判断性身体的做法。行为干预扎根于正念hass hass Hass HASS HOW NOW在小型试验中的承诺，但仅在年轻人中女性。在第一阶段的性欲低下的年龄较低。由主要的研究者和利益相关者的咨询，以适应阶段的正念 2，五十名妇女将被随机分配到适应性的间隔或有关一般健康的教育控制小组和老化。饱和度，将对研究的发现进行评估。改编干预措施。 “研究社会，心理和生理学的整合方法对健康和良好的影响在生活过程中。” 妇女的性生活。生活和与衰老的基本社会关系。