Lymphatic Conference

淋巴会议

• 批准号: 9261242
• 负责人: GUILLERMO C OLIVER
• 金额: $ 2万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9261242
• 关键词: Animal Model; Area; Basic Science; Biology; Biomedical Engineering; Cardiovascular Diseases; Chicago; Clinical; Clinical Research; Clinical Trials; Collaborations; Defect; Development; Disease; Epigenetic Process; Experimental Models; Fostering; Functional disorder; Generations; Glaucoma; Growth; Health; Heart Diseases; Homeostasis; Hypertension; Illinois; Imaging Device; Immunologic Surveillance; Inflammation; Lipids; Liquid substance; Lymphatic; Lymphatic Diseases; Lymphatic vessel; Lymphedema; Malignant Neoplasms; Metabolism; Modeling; Nanotechnology; Obesity; Paper; Participant; Pathologic; Patients; Physicians; Play; Postdoctoral Fellow; Public Health; Publishing; Regulation; Research; Research Personnel; Role; Scientist; Series; Sodium Chloride; Stem cells; Students; Surface; Therapeutic; Time; Vision; Work; absorption; career; comparative; experience; graduate student; insight; interest; medical schools; meetings; nano; nervous system disorder; novel; posters; programs; symposium; tool

Project Summary This application is to request partial support of the inaugural NAVBO-LE&RN Lymphatic Conference that will take place at Northwestern Medical School in Chicago, Illinois on June 8-11, 2017. Research in lymphatic biology has experienced a dramatic growth within the last 10 years. This can be seen through the increase in the number of investigators, thanks to the emergence of a new generation of researchers, as well as through the increase in the number of investigators who, although working in other topics, have incorporated lymphatic-related questions into their interests. This growth is due, in part, to the identification of critical regulators of lymphatic growth and the availability of animal models, and to a better understanding of the functional roles of the lymphatic vasculature in health and disease. Lymphatic function has been primarily associated with lipid absorption, fluid/macromolecular homeostasis, and immune surveillance, and lymphatic vessel dysfunction has been associated with pathologic conditions such as lymphedema. However, recent work identified novel functional roles of the lymphatic vasculature in metabolism, obesity, inflammation, the regulation of salt storage in hypertension, heart disease, glaucoma and possibly even in some neurological disorders. Therefore, there is a dramatically increasing need for researchers working in a broad spectrum of normal and pathological lymphatic conditions. Along with the growth of the field and recognition of the public health importance of lymphatic diseases, there is a need for more frequent forums to exchange scientific progress and ideas in related topics that could bring together developmental biologists, cancer researchers, physiologists, biomedical engineers, cardiologists, neuroscientists and physicians. Such forums will help to promote the current progress in the identification and better characterization of lymphatic related disorders. Until now, the main lymphatic research conference was the one organized by the GRC every two years since 2004. Although a comparatively young GRC conference, attendance at the meeting has grown steadily since its inception and the number of applications for the last one in 2016, exceeded by 25 the maximum number of allowed participants (200). Accordingly, it has become apparent that there is a need to add a second major biennial lymphatic conference that can alternate with the established GRC. Therefore, this initial Lymphatic Conference will set the tone for those that will follow, as we expect that this series will also become a tradition in years to come. As seen in the proposed program, the selected speakers not only cover many of the major research topics, but will also put a special emphasis on the novel functional areas of lymphatic research, such as metabolism, neurological disorders, vision and cardiovascular diseases. It will also bring together basic and clinical scientists, as we will dedicate two sessions to discuss a variety of lymphatic-related pathological disorders. To make this conference broader and to foster interactions with researchers in other topics, an entire session will be devoted to emerging areas, such as stem cells, epigenetics and nanotechnology.

项目摘要 本申请是要向首届NAVBO-LE＆RN淋巴会议要求部分支持，该会议将 2017年6月8日至11日在伊利诺伊州芝加哥的西北医学院举行。淋巴生物学研究 在过去的十年中，经历了巨大的增长。可以通过数字增加来看出这一点 由于新一代研究人员的出现以及通过增加 尽管从事其他主题工作，但研究人员的数量已包含了与淋巴相关的问题 感兴趣。这种增长部分归因于鉴定淋巴生长的关键调节剂和 动物模型的可用性，以及更好地理解淋巴管的功能作用 在健康和疾病中。淋巴功能主要与脂质吸收相关， 液体/大分子稳态，免疫监测和淋巴血管功能障碍已是 与病理状况（例如淋巴水肿）相关。但是，最近的工作确定了新型功能 淋巴管的作用在代谢，肥胖，炎症，盐储存调节中的作用 高血压，心脏病，青光眼，甚至可能在某些神经系统疾病中。因此，有一个 对在广泛的正常和病理淋巴管中工作的研究人员的需求急剧增加 状况。随着领域的发展以及对淋巴发展的公共卫生重要性的认可 疾病，需要更频繁的论坛来交换相关主题的科学进步和思想 这可以汇集开发生物学家，癌症研究人员，生理学家，生物医学工程师， 心脏病学家，神经科学家和医生。这样的论坛将有助于促进当前的进展 鉴定和更好地表征淋巴相关疾病。到目前为止，主要淋巴研究 会议是自2004年以来GRC每两年组织一次的会议。 GRC会议以来，参加会议的出席人数一直在稳步增长 2016年最后一次的申请超过了25个允许参与者的最大数量（200）。 因此，显然需要添加第二次大型两年一次的淋巴大会 可以与已建立的GRC交替。因此，这次最初的淋巴会议将为 那些将跟随的人，正如我们期望的那样，本系列也将成为未来几年的传统。如在 拟议的计划，选定的演讲者不仅涵盖了许多主要的研究主题，而且还将提出 特别强调淋巴研究的新功能领域，例如代谢，神经学 疾病，视力和心血管疾病。它也将汇集基础和临床科学家，我们将 专门讨论各种淋巴相关的病理疾病。举行这次会议 更广泛并培养与其他主题中研究人员的互动，整个会议都将致力于新兴 区域，例如干细胞，表观遗传学和纳米技术。