Implementation of a pancreas knowledgebase

胰腺知识库的实施

• 批准号: 8539515
• 负责人: James Hilton
• 金额: $ 4.41万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8539515
• 关键词: Affect; American; Antibodies; Area; Bioinformatics; Biology; Book Chapters; Cellular Structures; Communities; Copyright; Country; Data Security; Development; Directories; Disease; Electronics; Exocrine pancreas; Foundations; Funding; Future; General Population; Health; Individual; Internet; Joints; Knowledge; Libraries; Link; Maintenance; Malignant neoplasm of pancreas; Medicine; Michigan; Mus; Names; Occupations; Pancreas; Pancreatic Diseases; Pancreatitis; Pathology; Pathway interactions; Peer Review; Printing; Procedures; PubMed; Publications; Published Comment; Published Directory; Reading; Request for Applications; Request for Proposals; Research; Research Methodology; Research Personnel; Resources; Schools; Site; Societies; Source; Structure; Surveys; System; Universities; Update; Viral Vector; Work; cell type; cost; data integrity; design; digital; editorial; interest; journal article; knowledge base; meetings; member; tool; web page

DESCRIPTION (provided by applicant): This proposal requests support to construct and implement an electronic resource for information on the exocrine pancreas. This pancreas knowledge base will be called "The Pancreapedia". It is designed to compile and curate knowledge on the exocrine pancreas, its component cell types and its diseases including pancreatitis and pancreatic cancer. It will also encourage new research and promote sharing of methods and research tools. It will contain six major divisions: Reviews, Pathways, Molecule Pages, Cell Structure, Research Tools, and People (Directory, community bulletin board). Content will be divided into "Entries" and "Posts". Entries will be invited or submitted and managed by Editors and an Editorial Board that will carry out peer review. After acceptance, staff will format and mount the finished copy which will be accompanied by a version number, date and digital object identifier (DOI). Material will be hyperlinked to other relevant areas in the site and to sites outside such as PubMed and NCBI. Material can be updated when ever appropriate but when content is changed it will be given a new date and version number. Posts will be entered directly onto a structured web page by individuals who have registered as members and will include Directory Listings, Research Tools (mouse lines, viral vectors, antibodies) and Comments. Comments can be made on all entries and will be accompanied by the commenter's name and picture. The site is constructed using Drupal as the content management system with the aim of minimizing the work of putting up new content. It will be mounted on a server at the University of Michigan Library (MPublishing) which will be the Publisher and responsible for data security and integrity. All content will be open access with the copyright remaining with the author. After establishment of the resource funds to cover the cost of maintenance and putting up new content will come from The American Pancreatic Association and other organizations (Societies and Foundations) interested in pancreatic research.

描述（由申请人提供）：该提案请求支持构建和实施外分泌胰腺信息的电子资源。这个胰腺知识库将被称为“The Pancreapedia”。它旨在汇编和整理有关外分泌胰腺、其组成细胞类型及其疾病（包括胰腺炎和胰腺癌）的知识。它还将鼓励新的研究并促进方法和研究工具的共享。它将包含六个主要部分：评论、途径、分子页面、细胞结构、研究工具和人员（目录、社区公告板）。内容将分为“条目”和“帖子”。参赛作品将由编辑和编辑委员会邀请或提交和管理，并进行同行评审。验收后，工作人员将格式化并安装完成的副本，该副本将附有版本号、日期和数字对象标识符 (DOI)。材料将通过超链接链接至网站内的其他相关区域以及 PubMed 和 NCBI 等外部网站。材料可以在适当的时候进行更新，但是当内容发生更改时，将会给出新的日期和版本号。帖子将由注册为会员的个人直接输入到结构化网页上，其中包括目录列表、研究工具（鼠标线、病毒载体、抗体）和评论。可以对所有参赛作品发表评论，并附有评论者的姓名和照片。该网站是使用 Drupal 作为内容管理系统构建的，目的是最大限度地减少发布新内容的工作。它将安装在密歇根大学图书馆 (MPublishing) 的服务器上，该服务器将作为发布者并负责数据的安全性和完整性。所有内容都将开放获取，版权归作者所有。在建立用于支付维护费用和发布新内容的资源基金后，美国胰腺协会和其他对胰腺研究感兴趣的组织（学会和基金会）将提供这些资金。