Interfacing computation and engineering with digestive and metabolic physiology

将计算和工程与消化和代谢生理学相结合

基本信息

批准号：
8999386
负责人：
Santiago Schnell
金额：
$ 10.8万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2021-01-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8999386
关键词：
Address Advisory Committees Animal Model Area Award Bachelor&apos s Degree Big Data Biomedical Research Caenorhabditis elegans Complex Diabetes Mellitus Digestive System Disorders Discipline Disease Doctor of Philosophy Drosophila melanogaster Educational process of instructing Engineering Enrollment Ethics Evaluation Faculty Fellowship Program Genomics Goals Health Interdisciplinary Study Laboratory Research Link Liver diseases Malignant Neoplasms Manuscripts Mathematics Mentors Mentorship Metabolic Metabolic Diseases Metabolism Michigan Mission Molecular Monitor Mus National Institute of Diabetes and Digestive and Kidney Diseases Obesity Oral Paper Physics Physiological Physiology Positioning Attribute Proteomics Public Health Publishing Qualifying Recommendation Recruitment Activity Reporting Research Research Personnel Research Project Grants Science Scientist Series Student Selections Students System Technology Training Transcend Transgenic Organisms Travel United States National Institutes of Health Universities Work Zebrafish career computerized tools education research experience genomic data innovation interest lectures medical schools metabolomics minority student multi-scale modeling next generation programs public health relevance statistics student mentoring success summer research symposium tool undergraduate student

项目摘要

DESCRIPTION (provided by applicant): The overall long-term goal of our R25 Educational Program "Interfacing computation and engineering with digestive and metabolic physiology" is to attract and encourage undergraduate students who are majoring in engineering, quantitative and computational disciplines to consider careers in digestive health and metabolism and their related diseases. The program is sponsored by the Department of Molecular & Integrative Physiology at the University of Michigan and includes 21 mentors. The focus of this renewal application is to continue but expand the annual summer research fellowship program referred to as STEP (Short Term Educational Program) from 8 to 11 students per summer. During the past four years, we evaluated 119 applications and enrolled 32 different students from across the US, from whom 6 were fellows for 2 years. To maximize the experience, students are encouraged to enroll in two consecutive summers if possible. Notably, 5 of the 6 students who participated in two summers have published at least one paper with their research mentors; 9 of the 32 students are coauthors on at least one manuscript; and 71% of our fellows who have finished their undergraduate degree are attending graduate or medical schools, or hold technical positions in academic biomedical research settings. Our 10 week fulltime summer research experience incorporates a noon lecture series that teaches important physiology and research-related principles, including the use of different model organisms, ethics in laboratory research, and career opportunities in biomedical sciences. The research experience culminates in a mini-symposium, with oral presentations given by the students that summarize their research projects. To further enhance our students' experience, we are incorporating to the program conference travel awards to promote the personalized mentor-trainee relationship beyond the summer; and an alumni mentorship program to link former program fellows, who are pursuing advanced degrees, with actively enrolled STEP students. The Educational Program will continue to be under the oversight of a highly qualified Advisory Committee, and student selection and progress monitoring will be done by a Student Selection and Mentoring Committee. The 2012 NIH Biomedical Workforce estimates that quantitative and computational scientists make up less than 2% of the biomedical science workforce. Therefore, training of quantitative scientists is critical for the advancement of biomedical sciences, especially in the era of big data including complex genomics and proteomics, and multi-scale physiological systems. Our program provides excellent opportunities for undergraduate students from quantitative scientific disciplines to perform laboratory research. We expect this experience to instill excitement and to propel the students to pursue biomedical research- oriented careers, particularly in NIDDK-focused areas of digestive health, metabolism and related diseases. Given what we have accomplished during the past 4 years, and the improvements we propose to implement, we anticipate being able to contribute to the next generation of highly accomplished biomedical scholars.

描述（通过应用程序提供）：我们的R25教育计划的总体长期目标“与消化代谢生理学接触和工程学”是为了吸引和鼓励那些正在培养，定量和计算的学生来考虑在消化健康和代谢中的职业与密歇根州的大学相关，包括21个导师。我们的6年来了2年。已经完成了他们的本科毕业生或医学院的医学研究环境，我们的10周全职夏季都结合了一个中午的讲座系列，教授重要的生理学和与耳朵有关的原则，包括使用“用途”座谈会由学生提供的研究因此，在高度委员会委员会的监督下。考虑到我们在过去的4个中所取得的成就以及我们建议实施的改进，我们预计能够为下一代一代备受熟练的成就贡献贡献，以促进刺激促进促进生物医学职业的促进生物医学职业，这是在以NIDDK为注重的消化健康领域。生物医学学者。