SMS scheduled gradual reduction text messages to help pregnant smokers quit

短信预定逐步减少短信帮助怀孕吸烟者戒烟

• 批准号: 9081546
• 负责人: KATHRYN I POLLAK
• 金额: $ 59.65万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9081546
• 关键词: Abstinence; Back; Behavioral; Birth; Cellular Phone; Cigarette; Cognitive; Counseling; Coupled; Cues; Data; Female of child bearing age; Fetus; Health; Household; Intervention; Lead; Learning; Literature; Methods; Mothers; Motivation; Outcome; Outcome Measure; Pilot Projects; Postpartum Period; Pregnancy; Pregnant Women; Premature Birth; Public Health; Randomized; Reporting; Risk; Sampling; Schedule; Self Efficacy; Smoke; Smoker; Smoking; Testing; Text; Time; Weaning; Woman; Work; arm; base; design; effective intervention; efficacy testing; expectation; fetal tobacco exposure; improved; innovation; member; pregnant; primary outcome; programs; racial diversity; randomized trial; secondary outcome; self help; smoking cessation; two-arm trial

Smoking in pregnancy poses serious health risks to the fetus and mother. Unfortunately, about half of women continue to smoke when becoming pregnant; this rate has not decreased significantly in the past decade. Effective interventions clearly are needed. Promisingly, most women reduce smoking when learning of their pregnancy, and most report desiring to quit via reduction rather than cold turkey. However, self-weaning often is ineffective and undermines total cessation efforts. Scheduled gradual reduction (SGR) might be an effective way to promote cessation among pregnant women. SGR, along with cognitive behavioral counseling, has been shown to help non-pregnant smokers quit above cold turkey or self-weaning methods. SGR might be ideally delivered via a method like SMS text messaging, with which most pregnant smokers are familiar. Our pilot work shows feasibility, acceptability, and preliminary efficacy of this SGR + CBT program. The end product of this work would a disseminable ready-to-be-implemented program. The proposed five-year study is designed to evaluate the efficacy of SGR plus CBT via SMS text messaging in promoting smoking cessation among a racially diverse sample of pregnant smokers. Proposed is a two-arm randomized controlled design. Eligible pregnant women (N=522, 261 per arm) will be randomized to: Arm 1, SGR via SMS text messaging plus SMS Support Messages and self-help materials (n=261) or Arm 2, SMS Support Messages and self-help materials (n=261). The primary outcome measure is biochemically validated 7-day point prevalent abstinence at the end of pregnancy. Secondary outcomes are prolonged abstinence at the end of pregnancy, biochemically-validated smoking reduction during pregnancy, smoking abstinence at 3-months postpartum, and preterm birth. The significance of this project is that no easily disseminable effective programs exist to help pregnant women quit smoking. An automated, tailored text messaging intervention shows promise to reach many pregnant women and reduce smoking during pregnancy.

怀孕期间吸烟会给胎儿和母亲带来严重的健康风险。不幸的是，大约一半的女性在怀孕期间继续吸烟；过去十年中这一比率并没有显着下降。显然需要有效的干预措施。令人欣慰的是，大多数女性在得知自己怀孕后都会减少吸烟，而且大多数女性表示希望通过减少吸烟量而不是突然戒烟来戒烟。然而，自我断奶通常是无效的，并且会破坏彻底戒烟的努力。计划逐步减量（SGR）可能是促进孕妇戒烟的有效方法。 SGR 与认知行为咨询相结合，已被证明可以帮助非怀孕吸烟者戒烟，胜过突然戒烟或自我戒烟方法。 SGR 的理想方式可能是通过短信等大多数怀孕吸烟者都熟悉的方法来传递。我们的试点工作表明了该 SGR + CBT 计划的可行性、可接受性和初步效果。这项工作的最终产品将是一个可传播、可立即实施的计划。拟议的为期五年的研究旨在评估 SGR 加 CBT 通过短信促进不同种族怀孕吸烟者戒烟的效果。提出的是双臂随机对照设计。符合条件的孕妇（N=522，每组 261 名）将被随机分配到：第 1 组，通过短信发送 SGR 加上 SMS 支持消息和自助材料（n=261）或第 2 组，SMS 支持消息和自助材料（n=261）。主要结果指标是经生化验证的妊娠结束时 7 天点普遍禁欲。次要结局是妊娠末期长期戒烟、经生化验证的妊娠期间吸烟减少、产后 3 个月戒烟以及早产。该项目的意义在于，目前还没有易于传播的有效方案来帮助孕妇戒烟。自动化、定制的短信干预措施有望惠及许多孕妇并减少怀孕期间吸烟。