CIRI Oncology Research Alliance (CORA)

CIRI肿瘤学研究联盟（CORA）

• 批准号: 8902081
• 负责人: Dax Kurbegov
• 金额: $ 78万
• 依托单位: COMMONSPIRIT HEALTH RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8902081
• 关键词: Access to Information; Address; Adoption; Budgets; Cancer Center; Caring; Clinical Research; Clinical Trials; Communities; Community Clinical Oncology Program; Community Networks; Community Outreach; Country; Data; Databases; Detection; Education; Electronic Health Record; Enrollment; Ethnic Origin; Evaluation; Feeds; Glean; Goals; Growth; Guidelines; Health; Home environment; Human; Informed Consent; Institutes; Institutional Review Boards; Leadership; Learning; Legal; Link; Malignant Neoplasms; Marketing; Measurable; Minority Groups; Modeling; National Cancer Institute; Nurses; Office Management; Oncologist; Patients; Patterns of Care; Physicians; Population; Population Heterogeneity; Positioning Attribute; Process; Race; Research; Research Infrastructure; Research Institute; Research Support; Resources; Rural; Services; Site; Specimen; Structure; System; Target Populations; Testing; The Cancer Genome Atlas; Training; Translating; Translational Research; Underrepresented Minority; Underserved Population; anticancer research; base; cancer care; cancer prevention; care delivery; community setting; design; experience; health care delivery; improved; innovation; meetings; multidisciplinary; oncology; oncology service; personalized medicine; programs; prospective; quality assurance; research study; response; sample collection; screening; survivorship; symposium; tumor registry

DESCRIPTION (provided by applicant): The CHI Institute for Research and Innovation's Oncology Research Alliance (CIRI-CORA) uses a unique and innovative research model that optimizes the National Cancer Institute's community oncology research platform and incorporates best practices CHI's National Oncology Service Line instituted through the NCCCP. CORA capitalizes on the existing structure of our Institute for Research and Innovation (CIRI) and their system-wide clinical trials management system; standardized processes including a centralized IRB, informed consent management, and legal approvals; collaborative leadership and governance entity; unique network of community cancer centers with diverse populations, variable practices and geographic reach; staff education; aligned oncologists; best practices from the NCCCP, and a rigorous, prospective quality assurance program to provide the infrastructure needed to excel in community cancer research. Goals for CORA include: 1.) Increasing enrollment in cancer clinical trials by providing access to a wide portfolio of high quality research studies that meet the needs of our diverse and disparate populations. We will annually accrue 10% of our new cancer cases within target populations to research trials, 2.) Identifying, designing and implementing cancer care delivery research that leads to improved models of care and translates to high quality, value based services throughout the oncology continuum, and 3.) Expanding our efforts to explore and address the cancer care needs of racial and ethnic minorities as well as other defined disparate populations. CORA includes seven of CHI's market-based (care delivery) organizations across six states. CHI leadership developed CIRI in 2007 in response to the ever-increasing complexity of human cancer research and the lack of resources, expertise, or access that often characterize community based cancer programs. CIRI supports the conduct of standardized high quality clinical research in the community setting, exploring innovative models of health care delivery, and accelerating the adoption of personalized medicine through bio-specimen collection and evaluation.

描述（由申请人提供）：CHI 研究与创新研究所的肿瘤学研究联盟 (CIRI-CORA) 采用独特的创新研究模式，优化了国家癌症研究所的社区肿瘤学研究平台，并结合了 CHI 国家肿瘤学服务线通过建立的最佳实践NCCCP。 CORA 利用我们研究与创新研究所 (CIRI) 的现有结构及其全系统临床试验管理系统；标准化流程，包括集中式 IRB、知情同意管理和法律批准；协作领导和治理实体；独特的社区癌症中心网络，具有不同的人群、不同的实践和地理覆盖范围； 员工教育；一致的肿瘤学家； NCCCP 的最佳实践，以及严格的前瞻性质量保证计划，为社区癌症研究提供卓越所需的基础设施。 CORA 的目标包括： 1.) 通过提供广泛的高质量研究组合来增加癌症临床试验的注册人数，以满足我们多样化和不同人群的需求。我们每年将在目标人群中积累 10% 的新癌症病例进行研究试验，2.) 识别、设计和实施癌症护理提供研究，从而改进护理模式，并在整个肿瘤学连续体中转化为高质量、基于价值的服务和 3.) 加大力度探索和解决少数种族和族裔以及其他特定人群的癌症护理需求。 CORA 包括 CHI 位于六个州的七个基于市场的（护理提供）组织。 CHI 领导层于 2007 年创建了 CIRI，以应对人类癌症研究日益复杂的情况以及社区癌症项目通常缺乏资源、专业知识或渠道的情况。 CIRI支持在社区环境中开展标准化高质量临床研究，探索医疗保健服务的创新模式，并通过生物样本采集和评估加速个性化医疗的采用。