Research Program: Cancer Epidemiology, Prevention and Control

研究项目：癌症流行病学、预防与控制

基本信息

批准号：
8804795
负责人：
POLLY A NEWCOMB
金额：
$ 7.13万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-02-01 至 2019-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8804795
关键词：
Appointment Biological Markers Biometry Cancer Center Support Grant Cancer Survivorship Child Clinical Clinical Trials Clinical Trials Cooperative Group Communication Communities Contracts Data Discipline Faculty Funding General Population Genetic Genomics Goals Grant Health Policy Human Incidence Institution Internal Medicine Intervention Studies Laboratories Leadership Malignant Neoplasms Medical Oncology Medical Surveillance Mission Molecular Epidemiology Morbidity - disease rate Outcome Paper Peer Review Play Population Prevention Psychology Publishing Quality of life Recruitment Activity Research Research Contracts Research Personnel Research Project Grants Resource Sharing Resources Risk Reduction Role Scientist Screening for cancer Sociology Surveillance Methods Target Populations Testing Training Translating Treatment Effectiveness Underserved Population Women&apos s Health anticancer research base cancer epidemiology cancer therapy clinical practice cohort computer infrastructure genetic epidemiology health economics improved member mortality neoplasm registry next generation nutrition programs repository sound

项目摘要

Description and Lay Summary The Cancer Epidemiology, Prevention and Control (CEPC) Program seeks to reduce cancer incidence and mortality through research on environmental and genetic causes of cancer, early detection, risk reduction, and improved outcomes and quality of life. To accomplish this mission, our large, multi-disciplinary faculty conducts clinical and community-based studies in the general population, as well as in targeted and often underserved populations. The CEPC Program currently has 76 members from 14 departments and all three Consortium member institutions, representing multiple scientific disciplines, including epidemiology, genetics, sociology, psychology, internal medicine, medical oncology, communications, nutrition, biostatistics, and health economics. Thirty- nine CEPC faculty have primary appointments at FHCRC, 36 have primary appointments at UW, and one is based at Seattle Children's. CEPC faculty have been successful in obtaining independent funding to support their research: 93% have peer-reviewed cancer related research grants or contracts, are PI on a clinical trial, or are newly recruited investigators, resulting in a research portfolio (direct) totaling $25,984,344 in grants/contract funding, of which $21,616,050 is peer reviewed and $12,793,467 is from NCI. During the previous grant period, CEPC Program faculty published a total of 1655 papers, 25% of which were intra- programmatic, 32% were inter-programmatic, and 17% were inter-institutional. Important program resources include: the Puget Sound Surveillance Epidemiology and End Results (SEER) Cancer Registry, the Molecular Epidemiology and Biomarker Laboratories, large well-maintained cohorts such as the Women's Health Initiative (WHI), clinical trial groups including national coordinating centers, extensive data and biospecimen repositories, the Prevention Center Shared Resource, computational infrastructure and leadership, and nationally-recognized expertise with analysis and interpretation of genomic data. The CEPC Program continues to play an important role in the training of the next generation of cancer research/population scientists.

描述和概括癌症流行病学、预防和控制 (CEPC) 计划旨在减少癌症发病率和通过研究癌症的环境和遗传原因、早期发现、降低风险和改善结果和生活质量。为了完成这一使命，我们庞大的多学科教师队伍在一般人群中进行临床和基于社区的研究，以及有针对性的和经常性的研究服务不足的人群。 CEPC 计划目前拥有来自 14 个部门的 76 名成员以及所有三个联盟成员代表多个科学学科的机构，包括流行病学、遗传学、社会学、心理学、内科、肿瘤内科、传播学、营养学、生物统计学和卫生经济学。三十- 9 名 CEPC 教员在 FHCRC 担任主要职务，36 名在 UW 担任主要职务，1 名是总部设在西雅图儿童医院。 CEPC 教师已成功获得独立资金来支持他们的研究：93% 拥有经过同行评审的癌症相关研究资助或合同，是临床试验的 PI，或者是新招募的研究人员，导致研究组合（直接）总计 25,984,344 美元赠款/合同资金，其中 21,616,050 美元经过同行评审，12,793,467 美元来自 NCI。期间上一个资助期，CEPC 项目教师总共发表了 1655 篇论文，其中 25% 是内部论文项目间的，32% 是项目间的，17% 是机构间的。重要的计划资源包括：普吉特湾流行病学监测和最终结果 (SEER) 癌症登记处、分子流行病学和生物标志物实验室，维护良好的大型实验室，例如妇女健康实验室倡议 (WHI)、包括国家协调中心在内的临床试验小组、广泛的数据和生物样本存储库、预防中心共享资源、计算基础设施和领导力，以及国家认可的基因组数据分析和解释专业知识。 CEPC计划继续在下一代癌症研究/人群的培训中发挥重要作用科学家。