Community Mobilization and HIV/STI Epidemiology of Female Sex Workers in Mexico

墨西哥女性性工作者的社区动员和艾滋病毒/性传播感染流行病学

• 批准号: 8820248
• 负责人: Lianne A Urada
• 金额: $ 18.76万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8820248
• 关键词: AIDS prevention; Address; Advocacy; Advocate; Affect; Alcohol consumption; Alcohol dependence; Alcohol or Other Drugs use; Applications Grants; Attention; Behavior; Behavioral; Biological; Biological Markers; Border Crossings; California; Caribbean region; Cities; Coercion; Communities; Community Workers; Conscious; Cost-Benefit Analysis; Data; Data Analyses; Data Collection; Dependence; Development Plans; Diffuse; Drug usage; Ensure; Epidemiology; Ethics; Evaluation Methodology; Event; Face; Female; Focus Groups; Forcible intercourse; Funding; Future; General Population; Goals; Guidelines; HIV; HIV Infections; HIV risk; HIV/STD; Harm Reduction; Health; Health Services Accessibility; Human Rights; Illicit Drugs; India; Individual; Infection; International; Intervention; Intervention Studies; Interview; Knowledge; Lead; Learning; Literature; Marijuana; Measurement; Measures; Mentored Research Scientist Development Award; Mentors; Methods; Mexico; Modeling; National Institute of Drug Abuse; Nature; Needles; Outcome; Pharmaceutical Preparations; Police; Population; Positioning Attribute; Prevalence; Prevention; Preventive Intervention; Public Health; Publishing; Readability; Recording of previous events; Reporting; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Rights; Risk; Risk Behaviors; Role; Shares syringes; Surveys; Syringes; Testing; Time; Training; United States; Universities; Unsafe Sex; Victimization; Violence; Vulnerable Populations; Woman; Work; World Health Organization; base; career; career development; clinical epidemiology; cognitive testing; design; empowerment; experience; follow-up; high risk; improved; injection drug use; interest; parent grant; peer; programs; sex; sex risk; skills; social; solidarity; substance abuse epidemiology; transmission process

DESCRIPTION (provided by applicant): This Mentored Research Scientist Development Award (K01) will enable me to 1) acquire expertise in the research methods of developing structural HIV prevention interventions targeting substance using female sex workers (FSWs); 2) increase knowledge of substance abuse epidemiology, assessment and prevention; 3) obtain additional training in the culturally competent ethical conduct of research involving behavioral and biological HIV/STI data collection, violence measurement, and structural interventions in a new international setting; 4) learn how to design RCTs of interventions and conduct related longitudinal data analyses (GLMM); 5) hone skills needed for a successful academic career studying the intersection of substance use, HIV/STI acquisition, and structural risk and protective factors among high risk populations, including grantsmanship and disseminating scientific research findings nationally and internationally. My career development plan will include a mixture of didactic courses, seminars, hands-on field research experience, and mentored independent studies which will provide me with training in intervention evaluation methodologies, substance use epidemiology, and clinical biomarkers. For example, I will take courses in longitudinal data analyses (e.g. event history and survival, and cost-benefit analyses). I will work with a world-renowned mentoring team and an infrastructure already in place in Mexico, with the goal of applying what I learn to other national contexts as well. I will train in intervention adaptation while simultaneously practicing rigorous RCT evaluation methodologies (Generalized Linear Mixed Modeling (GLMM)) on existing data, with the goal of becoming one of a few structural HIV prevention intervention researchers for FSWs worldwide. My proposed K01 project "Mujeres Unidas" (Women United) will be embedded in the NIDA funded parent grant, "Proyecto Mapa de Salud" (R01DA028692-01, PI: Brouwer), which explores HIV/STI transmission among FSWs and other vulnerable populations along the Mexico/U.S. border. In Tijuana, Mexico, Mujeres Unidas will 1) qualitatively interview FSWs (N=30) and FSW advocates/organizers (N=20) about community mobilization and the role of substance use; 2) adapt measures of community mobilization to the Tijuana context through cognitive testing with FSWs (n=10) to ensure readability and acceptability, and 3) determine the prevalence of community mobilization participation and its association with substance use, HIV/STI prevalence and sexual risk behaviors among FSWs by adding adapted measures to the parent grant's 12- month follow up surveys (N=300 FSWs). Results will generate pilot data for a future R34 grant application to pilot/feasibility test an adapted preventive intervention targeting drug use and HIV infection acquisition.

描述（由申请人提供）：这一指导的研究科学家发展奖（K01）将使我获得1）获得了使用女性性工作者（FSWS）针对针对物质的研究方法的研究方法的专业知识； 2）增加对滥用药物的知识流行病学，评估和预防； 3）在新国际环境中的行为和生物HIV/STI数据收集，暴力测量和结构性干预措施中，获得涉及行为和生物HIV/STI数据收集行为和生物HIV/STI数据的研究的额外培训； 4）了解如何设计干预措施的RCT并进行相关的纵向数据分析（GLMM）； 5）成功的学术职业所需的磨难技能，研究了物质使用，艾滋病毒/性传播感染的交集，艾滋病毒/性传播疾病的相交以及高风险人群中的结构性风险和保护因素，包括助学士和在国内和国际上传播科学研究发现。我的职业发展计划将包括教学课程，研讨会，动手实地研究经验以及指导的独立研究的混合，这将为我提供干预评估方法，药物使用流行病学和临床生物标志物的培训。例如，我将参加纵向数据分析（例如事件历史和生存以及成本效益分析）的课程。我将与一个世界知名的指导团队和已经在墨西哥建立的基础设施合作，目的是将我学到的知识也应用于其他国家环境。我将对现有数据进行严格的RCT评估方法（广义线性混合建模（GLMM））同时培训干预适应，同时培训了现有数据，目的是成为全球FSWS的少数结构性HIV预防干预研究人员之一。我提出的K01项目“ Mujeres Unidas”（妇女联队）将嵌入NIDA资助的父母赠款“ Proyecto Mapa de Salud”（R01DA028692-01，PI：BROUWER）中，探索了FSWS和MEDECODO中的其他易害人群中的HIV/STI传输。边界。在墨西哥的蒂华纳，穆耶雷斯unidas将1）定性采访FSW（n = 30）和FSW倡导者/组织者（n = 20），涉及社区动员和药物使用的作用； 2）通过对FSWS（n = 10）进行认知测试来调整社区动员的措施，以确保可读性和可接受性，3）确定社区动员参与的普遍性及其与毒品使用，HIV/STI的患病性，HIV/STI的普遍性和性风险行为的关联，通过将FSW之间的FSW置于父母的批准中，以表达3个月的in = 3-ANT SURS SURS SURS SURS SURS SURS SURS SURS SURS SURS = 3-ANT = 3-3个月份（通过= 3个月份）。结果将生成未来R34授予申请的试点数据 吸毒和艾滋病毒感染的获取。