Evoked Potentials and Music Perception: Effects of Hearing Loss and Training

诱发电位和音乐感知：听力损失和训练的影响

• 批准号: 8516497
• 负责人: Carolyn J Brown
• 金额: $ 30.48万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-01 至 2015-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8516497
• 关键词: Accounting; Acoustic Nerve; Acoustics; Adult; Age; Arts; Auditory; Auditory Perception; Auditory area; Auditory system; Characteristics; Child; Childhood; Clinical Management; Cochlear Implants; Code; Complex; Development; Effectiveness; Environment; Evoked Potentials; Generations; Hearing; Hearing Aids; Human; Individual; Intervention; Investigation; Lead; Life; Measures; Music; Nervous system structure; Noise; Outcome; Perception; Performance; Peripheral; Persons; Play; Population; Principal Investigator; Process; Recording of previous events; Relative (related person); Research; Resolution; Role; Series; Signal Transduction; Speech; Speech Perception; Stimulus; Structure; Techniques; Training; Training Programs; Variant; auditory pathway; base; behavior measurement; behavior test; comparison group; computerized data processing; experience; hearing impairment; improved; interest; programs; rehabilitation strategy; relating to nervous system; research study; response; sound; speech accuracy; speech processing; therapy design

DESCRIPTION (provided by applicant): In everyday life, humans are regularly exposed to and must make sense of complex acoustical sounds in their environment. While many hearing aid (HA) and cochlear implant (CI) users enjoy fairly accurate speech perception in quiet, they often experience difficulties when listening to more spectrally complex stimuli, such as music, a pervasive and culturally significant art form, and speech in background noise. These limitations are likely related to the signal processing of CIs as well as limitations in the central auditory pathways, particularly in pediatric populations with congenital hearing loss. Through investigation of complex acoustic signals at the auditory periphery, and the coding of those stimuli within the central auditory nervous system, we will deepen our understanding of why music and speech perception in noise is so challenging for hearing impaired listeners. In this study, we will investigate characteristics of the listener's auditory system, the acoustic signal input, as well as potential benefit of music training in relation to perception of spectrally complx sounds (music and speech in background noise). Our first specific aim defines the relationship between cortically generated evoked potentials, the acoustic change response, and perceptual measures of complex stimuli for a wide range of listeners, including normal hearing listeners, hearing aid users and CI recipients. In Aim 2, through within-subject comparisons, we will measure the effect that different CI signal inputs have on higher level processing of spectrally complex sounds within the auditory nervous system. Aim 3, which focus on the role of experience-dependent plasticity in perception, investigate the impact of musical training on evoked potentials and perception of music and of speech in background noise. These studies will help us to evaluate the relative benefits of specific training parameters for groups of CI recipients who vary in important factors (e.g., age, hearing profile and history), and will help us predict which individuals may benefit most from systematic training. In summary, these results could (a) expand our understanding of factors that impact perception of spectrally complex signals, (b) investigate benefits of musical training, (c) determine the extent to which training can be generalized to other tasks, like perception of speech in noise, and (d) lead to the development of more effective rehabilitation strategies.

描述（由申请人提供）：在日常生活中，人类经常接触并必须理解环境中复杂的声音。虽然许多助听器 (HA) 和人工耳蜗 (CI) 用户在安静的情况下享受相当准确的语音感知，但他们在聆听更复杂的频谱刺激时常常会遇到困难，例如音乐（一种普遍存在且具有文化意义的艺术形式）和背景语音噪音。这些限制可能与 CI 的信号处理以及中枢听觉通路的限制有关，特别是在先天性听力损失的儿科人群中。通过研究听觉外围的复杂声学信号以及中枢听觉神经系统内这些刺激的编码，我们将加深对为什么噪声中的音乐和语音感知对于听力受损的听众来说如此具有挑战性的理解。在这项研究中，我们将研究听众听觉系统的特征、声学信号输入，以及音乐训练与频谱复杂声音（背景噪声中的音乐和语音）感知相关的潜在好处。我们的第一个具体目标是为广大听众（包括正常听力听众、助听器用户和 CI 接受者）定义皮质产生的诱发电位、声学变化反应和复杂刺激的感知测量之间的关系。在目标 2 中，通过受试者内部比较，我们将测量不同 CI 信号输入对听觉神经系统内频谱复杂声音的高级处理的影响。目标 3 重点关注经验依赖性可塑性在感知中的作用，研究音乐训练对诱发电位以及背景噪声中音乐和言语感知的影响。这些研究将帮助我们评估特定训练参数对重要因素（例如年龄、听力状况和病史）各不相同的 CI 接受者群体的相对益处，并将帮助我们 预测哪些人可以从系统培训中受益最多。总之，这些结果可以（a）扩大我们对影响频谱复杂信号感知的因素的理解，（b）研究音乐训练的好处，（c）确定训练可以推广到其他任务的程度，例如感知噪音中的言语，(d) 导致制定更有效的康复策略。