Complementary Neurotoxicological Insights from Fish, Flies, Bees and Worms Symposium

来自鱼、苍蝇、蜜蜂和蠕虫研讨会的补充神经毒理学见解

基本信息

批准号：
8986146
负责人：
EDWARD D LEVIN
金额：
$ 0.3万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-07-01 至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8986146
关键词：
Academia Academic Medical Centers Animal Model Archives Area Bees Behavioral Caenorhabditis elegans Chemicals Clinical Continuing Education Development Drosophila genus Epidemiology Evaluation Exposure to Fishes Fostering Funding Future Genetic study Government Heavy Metals In Vitro Industry Insecta Institutes International Invertebrates Journals Medical center Memory Modeling National Institute of Environmental Health Sciences National Toxicology Program Nematoda Neurotoxins Ontario Peer Review Pesticides Postdoctoral Fellow Principal Investigator Quebec Research Research Methodology Research Personnel Resources Risk Science Scientist Solvents Students Teratology Testing Toxic Environmental Substances Toxic effect Toxicant exposure Toxicology Travel United States Environmental Protection Agency Universities Work Writing Zebrafish base fly insight meetings neurobehavioral neuromechanism neurotoxicity neurotoxicology public health relevance screening symposium

项目摘要

DESCRIPTION (provided by applicant): The purpose of the International Neurotoxicity Association (INA) is to foster the science of determining the neural mechanisms and behavioral consequences of toxicants exposure. The bi- annual meeting (the 15th) is held for all in the field to communicate their latest research findings to their colleagues for continuing education and critical evaluation and to provide a forum for discussion of the current progress and directions for the future. INA would like to conduct a symposium with its annual meeting June 27-July 1, 2015 in Montreal, Quebec entitled "Complementary Neurotoxicologically Insights from Fish, Flies, Bees, and Worms." This symposium will provide the latest information concerning the use of aquatic, insect, and nematode models as complementary models for neurobehavioral toxicology research. The speakers will include internationally renowned researchers. This symposium will provide integration of mechanistic research with animal models of neurobehavioral function. The speakers for the symposium will be Edward Levin, Duke University Medical Center, Stephanie Padilla from the US-Environmental Protection Agency and Martina Fenske from the Fraunhofer Institute and will speak about how zebrafish help with screening potential neurotoxicants; Philip Bushnell from the US-Environmental Protection Agency will speak about using drosophila for studying genetic contributions to solvent neurotoxicity; Dr. Nigel Raine from the University of Guelph in Ontario will speak about pesticide effects on memory in bees and Michael Aschner from Albert Einstein Medical Center will speak about C. elegans heavy metal neurotoxicology; Dr. Mamta Behl of the National Toxicology and National Institute of Environmental Health Sciences will give an additional talk about how non-mammalian animal models fit into neurotoxicology testing in the National Toxicology Program.. Recent breakthroughs and research challenges will be discussed so that an intelligent agenda for neurobehavioral toxicology research in the area can be devised. The audience will be scientists active in developmental neurobehavioral toxicology research. Bringing the intellectual resources and research methods of the scientists in this field to use zebrafish, insect and nematode models will greatly enhance our ability to characterize risks that may be posed by exposure to environmental toxicants. The forum will provide an opportunity for methodological and theoretical issues to be integrated in the context of each talk as well as in a discussion session. Funding is needed for travel of non-government speakers and accommodations. Importantly, for continuing progress the Principal Investigator asks for support of students and post-doctoral trainees to participate in the meeting. Special efforts will be made to increase diversity in the field through the trainee-sponsored travel to the meeting. A write-up of the symposium will be submitted to Neurotoxicology and Teratology, a leading peer-reviewed journal in the field.

描述（由申请人提供）：国际神经毒性协会 (INA) 的目的是促进确定有毒物质暴露的神经机制和行为后果的科学。该会议每两年举行一次（第 15 届），面向该领域的所有人。为了向同事传达他们的最新研究成果，以进行继续教育和批判性评估，并提供一个讨论当前进展和未来方向的论坛，INA 希望在 6 月 27 日至 7 月的年会上举办一次研讨会。 2015 年 1 月 1 日在魁北克省蒙特利尔举行，题为“来自鱼类、苍蝇、蜜蜂和蠕虫的补充神经毒理学见解”。本次研讨会将提供有关使用水生动物、昆虫和线虫模型作为神经行为毒理学研究补充模型的最新信息。演讲者将包括国际知名的研究人员。本次研讨会将提供机制研究与神经行为功能动物模型的整合。杜克大学医学中心的 Levin、美国环境保护署的 Stephanie Padilla 和弗劳恩霍夫研究所的 Martina Fenske 将谈论斑马鱼如何帮助筛查潜在的神经毒物；美国环境保护署的 Philip Bushnell 将谈论使用果蝇进行研究。研究溶剂神经毒性的遗传因素；安大略省圭尔夫大学的 Nigel Raine 博士将谈论农药对蜜蜂记忆的影响，以及阿尔伯特爱因斯坦医学中心的 Michael Aschner中心将讨论秀丽隐杆线虫重金属神经毒理学；国家毒理学和国家环境健康科学研究所的 Mamta Behl 博士将另外讨论非哺乳动物动物模型如何适应国家毒理学计划的神经毒理学测试。将讨论突破和研究挑战，以便为该领域的神经行为毒理学研究制定明智的议程。听众将是活跃于发育神经行为毒理学研究的科学家。该领域科学家使用斑马鱼、昆虫和线虫模型的智力资源和研究方法将极大地提高我们描述环境毒物暴露可能造成的风险的能力，该论坛将为研究方法和理论问题提供机会。重要的是，为了持续取得进展，首席研究员要求学生和博士后学员参与的支持。会议特别努力。将通过受训者赞助的会议旅行来增加该领域的多样性。研讨会的论文将提交给该领域领先的同行评审期刊《神经毒理学和畸胎学》。