Eastern Cooperative Oncology Group
东部肿瘤合作组
基本信息
- 批准号:8468646
- 负责人:
- 金额:$ 22.75万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1978
- 资助国家:美国
- 起止时间:1978-06-01 至 2015-02-28
- 项目状态:已结题
- 来源:
- 关键词:AwardBrain NeoplasmsBreastCancer CenterCellular biologyCervix UteriChestClinicalClinical ProtocolsClinical Research ProtocolsClinical TrialsCollaborationsComprehensive Cancer CenterContractsCorrelative StudyData QualityDevelopmentDiagnosisDiseaseEarly DiagnosisEastern Cooperative Oncology GroupFacultyGenitourinary systemGoalsGrantHead and neck structureLaboratoriesLeadershipLungLymphomaMalignant NeoplasmsMalignant neoplasm of prostateMissionModalityMolecular BiologyMultiple MyelomaPatientsPerformancePharmaceutical PreparationsPharmacologyPhasePreventionPublic HealthPublic Health SchoolsQuality of lifeRoleScienceStagingTranslational Researchcancer preventioncancer therapydrug developmentgastrointestinalimprovedinnovationinterdisciplinary approachleukemia/lymphomamembernovelscreeningtherapeutic developmentworking group
项目摘要
Johns Hopkins has been a member of ECOG since 1955. Our primary goal is to bring innovative clinical research protocols and laboratory correlative science piloted at Johns Hopkins to the Group for further development. In conjunction with this, our faculty serve in leadership roles as study chairs and laboratory co-chairs, disease and modality-oriented committee chairs.
The specific aims are: 1) to continue to provide scientific leadership in the disease-oriented committees: Breast, Thoracic, Head and Neck, Genitourinary, Brain Tumor Working Group, Lymphoma, Leukemia; 2) to continue to expand our involvement in the disease and modality committees: Gastrointestinal, Myeloma, Pharmacology and Drug Development; to bring translational research correlates, cell biology and molecular biology into clinical protocols for all stages of disease; 4) to continue to expand accrual, and to maintain excellent performance in data quality.
These goals will be accomplished through the mission of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: to provide a multidisciplinary approach to the study of cancer that will result in improved means for prevention, diagnosis, and treatment. The Center has achieved excellence in translational research with the awarding of seven SPORE grants (cervix, lymphoma, G-l cancer, prostate, breast, lung, head and neck). In addition, early clinical trials of new drugs are conducted under the NCI phase I contract (since 1982). The Early Therapeutics Development with Phase II Emphasis grants allow the development of novel phase II and phase III concepts which the Cancer Center faculty bring to ECOG with appropriate laboratory science correlative studies. The expansion of Center facilities allows the development of new clinical prograins, the recruitment of new faculty, furthering committee involvement and clinical trial accrual.
约翰·霍普金斯大学自 1955 年以来一直是 ECOG 的成员。我们的主要目标是将约翰·霍普金斯大学试点的创新临床研究方案和实验室相关科学引入该集团,以供进一步发展。与此同时,我们的教师担任研究主席和实验室联合主席、疾病和模式导向委员会主席等领导角色。
具体目标是: 1) 继续在以疾病为导向的委员会中提供科学领导:乳腺、胸腔、头颈、泌尿生殖、脑肿瘤工作组、淋巴瘤、白血病; 2) 继续扩大我们对疾病和模式委员会的参与:胃肠道、骨髓瘤、药理学和药物开发;将相关转化研究、细胞生物学和分子生物学纳入疾病各个阶段的临床方案; 4)继续扩大应计规模,保持数据质量优良表现。
这些目标将通过约翰·霍普金斯大学西德尼·金梅尔综合癌症中心的使命来实现:提供多学科方法来研究癌症,从而改善预防、诊断和治疗的手段。该中心在转化研究方面取得了卓越成就,获得了七项 SPORE 资助(子宫颈癌、淋巴瘤、G-1 癌、前列腺癌、乳腺癌、肺癌、头颈癌)。此外,新药的早期临床试验是根据NCI I期合同(自1982年起)进行的。以第二阶段为重点的早期治疗开发拨款允许开发新的第二阶段和第三阶段概念,癌症中心教师通过适当的实验室科学相关研究将这些概念带到ECOG。中心设施的扩建允许开发新的临床项目、招募新的教职人员、促进委员会的参与和临床试验的积累。
项目成果
期刊论文数量(18)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Assessing the Involvement of Users During Development of Lower Limb Wearable Robotic Exoskeletons: A Survey Study.
评估用户在下肢可穿戴机器人外骨骼开发过程中的参与度:一项调查研究。
- DOI:
- 发表时间:2020
- 期刊:
- 影响因子:3.3
- 作者:Ármannsdóttir, Anna L;Beckerle, Philipp;Moreno, Juan C;van Asseldonk, Edwin H F;Manrique;Del;Veneman, Jan F;Briem, Kristín
- 通讯作者:Briem, Kristín
Randomized prospective comparison of intraventricular methotrexate and thiotepa in patients with previously untreated neoplastic meningitis. Eastern Cooperative Oncology Group.
脑室内注射甲氨蝶呤和塞替派治疗既往未经治疗的肿瘤性脑膜炎患者的随机前瞻性比较。
- DOI:10.1200/jco.1993.11.3.561
- 发表时间:1993-03-01
- 期刊:
- 影响因子:0
- 作者:S. Grossman;D. Finkelstein;J. Ruckdeschel;D. Trump;T. Moynihan;D. Ettinger
- 通讯作者:D. Ettinger
A phase II study of Didemnin B (NSC 325319) in advanced malignant melanoma: an Eastern Cooperative Oncology Group study (PB687).
Didemnin B (NSC 325319) 治疗晚期恶性黑色素瘤的 II 期研究:东部肿瘤合作组研究 (PB687)。
- DOI:
- 发表时间:1998
- 期刊:
- 影响因子:3.4
- 作者:Hochster, H;Oratz, R;Ettinger, D S;Borden, E
- 通讯作者:Borden, E
Passive Back Support Exoskeleton Improves Range of Motion Using Flexible Beams.
被动背部支撑外骨骼利用柔性梁改善运动范围。
- DOI:
- 发表时间:2018
- 期刊:
- 影响因子:0
- 作者:Näf, Matthias B;Koopman, Axel S;Baltrusch, Saskia;Rodriguez;Vanderborght, Bram;Lefeber, Dirk
- 通讯作者:Lefeber, Dirk
Phase II study of cisplatin and 5-fluorouracil in previously treated metastatic breast cancer: an Eastern Cooperative Oncology Group study (PA 185).
顺铂和 5-氟尿嘧啶治疗既往治疗过的转移性乳腺癌的 II 期研究:东部肿瘤合作组研究 (PA 185)。
- DOI:
- 发表时间:1999-09
- 期刊:
- 影响因子:3.8
- 作者:Kucuk, O;Pandya, K J;Skeel, R T;Hochster, H;Abeloff, M D
- 通讯作者:Abeloff, M D
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{{ truncateString('ARLENE ANN FORASTIERE', 18)}}的其他基金
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