Training Attentional Awareness and Control in ADHD

训练注意力缺陷多动症的注意力意识和控制

• 批准号: 8597235
• 负责人: GREGORY V SIMPSON
• 金额: $ 39.97万
• 依托单位: THINK NOW, INC.
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-02 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8597235
• 关键词: Address; Adult; Attention; Attention deficit hyperactivity disorder; Awareness; Back; Behavior; Behavioral; Brain; Businesses; Clinical; Code; Cognitive; Collaborations; Control Groups; Data; Databases; Development; Devices; Disease; Educational process of instructing; Entrepreneurship; Exercise; Failure; Feeds; Feeling; Foundations; Funding; Glosso-Sterandryl; Goals; Grant; Guidelines; Individual; Information Systems; Internet; Learning; Legal patent; Life; Link; Medical Device; Methods; Mind; Modeling; Muscle; Online Systems; Outcome; Outcome Measure; Ownership; Performance; Phase; Randomized; Randomized Controlled Trials; Reading; Research; Schools; Science; Signal Transduction; Software Design; Symptoms; System; Techniques; Training; Translating; United States National Institutes of Health; base; brain research; cost; design; distraction; economic impact; efficacy testing; improved; inattention; innovation; lecturer; member; mind control; neurophysiology; programs; public health relevance; resilience; skills; success; tool; web site

DESCRIPTION (provided by applicant): Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly prevalent disorder, incurring billions of dollars of costs annually, for which there is a rel need for additional non-pharmacologic treatments. Deficits in maintaining attentional control manifest as inconsistent intra-individual performance on sustained attention tasks with periods of normal performance and other periods of poor performance thought to reflect "inattention", and is considered by several groups to be an important component of ADHD. Research by our team members on the behavioral and neurophysiological bases of sustaining attentional control reveal infra-slow fluctuations in performance and in brain signals related to sustained attention to targets, suppression of distractors and mind wandering. We have created an innovative (patent pending) product that directly targets these three components of sustained attentional control in ADHD. The Sustained Attentional Control (SAC) training utilizes the ubiquity of mobile-apps to train adults with ADHD in all contexts of real life. Our approach combines building attentional control skills with awareness of attentional control and includes active transfer of the experiential sense of three attentional control components to real life activities (sustained focus, suppression of distractions and mind wandering). This Phase-I project is aimed at demonstrating the efficacy of the SAC product for training sustained attentional control in adults with ADHD. In Aim-1 we build on the existing code framework of our current apps and the back-end data system, to complete the programming and artwork for the remaining set of training apps and optimize them for adults with ADHD. In Aim-2 we test the efficacy of SAC training - 100 subjects will be randomly assigned to either a Treatment Condition (SAC training), or Control Condition with equivalent app usage and contact, but without factors hypothesized to provide training benefits. We will determine the amount of improvement between Pre- and Post- Training in each condition and compare these improvements between Treatment and Control conditions using behavioral and neurophysiological outcome measures.

描述（由申请人提供）：注意力缺陷/多动障碍（ADHD）是一种非常普遍的疾病，每年产生数十亿美元的费用，因此相对需要额外的非药物治疗。维持注意力控制的缺陷表现为个体内部在持续注意力任务上的表现不一致，其中有正常表现的时期和其他表现不佳的时期，被认为反映了“注意力不集中”，并且被一些团体认为是 ADHD 的重要组成部分。我们的团队成员对维持注意力控制的行为和神经生理学基础进行的研究揭示了与对目标的持续注意力、干扰干扰的抑制和走神相关的表现和大脑信号的超慢波动。我们创造了一种创新（正在申请专利）产品，直接针对多动症持续注意力控制的这三个组成部分。持续注意力控制（SAC）训练利用无处不在的移动应用程序在现实生活的所有环境中训练患有多动症的成年人。我们的方法将培养注意力控制技能与注意力控制意识结合起来，包括将三个注意力控制组成部分的体验感主动转移到现实生活活动中（持续专注、抑制分心和走神）。该第一阶段项目旨在证明 SAC 产品在训练患有 ADHD 的成人持续注意力控制方面的功效。在 Aim-1 中，我们以当前应用程序和后端数据系统的现有代码框架为基础，完成其余训练应用程序集的编程和美工，并针对患有 ADHD 的成人进行优化。在 Aim-2 中，我们测试了 SAC 训练的功效 - 100 名受试者将被随机分配到治疗条件（SAC 训练）或具有同等应用程序使用和接触的控制条件，但没有假设提供训练益处的因素。我们将确定每种条件下训练前和训练后的改善量，并使用行为和神经生理学结果测量来比较治疗和控制条件之间的这些改善。