Predicting deficits in social competence for pediatric brain tumor survivors

预测儿科脑肿瘤幸存者的社交能力缺陷

基本信息

批准号：
8579326
负责人：
Kathryn Vannatta
金额：
$ 62.37万
依托单位：
RESEARCH INST NATIONWIDE CHILDREN'S HOSP
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-07-05 至 2018-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8579326
关键词：
Accounting Adult Affective Aftercare Age Attention Behavioral Buffers Cancer Burden Caring Child Childhood Brain Neoplasm Clinical Trials Cognitive Cognitive remediation Data Emotional Emotions Environment Evaluation Exclusion Family Fathers Female Friends Friendships Gender Goals Home environment Human Impaired cognition Impairment Intervention Knowledge Late Effects Lead Life Link Malignant Childhood Neoplasm Measures Mediating Medical Methods Mission Modeling Morbidity - disease rate Mothers Nature Nervous System Trauma Neuraxis Neurocognitive Neurocognitive Deficit Outcome Parent-Child Relations Parenting behavior Parents Pediatric Hospitals Performance Pharmaceutical Preparations Population Problem Solving Public Health Quality of life Questionnaires Race Radiation Recording of previous events Recruitment Activity Regulation Relative (related person)Reporting Research Resources Risk Schools Services Shapes Social Adjustment Social Behavior Social Interaction Social Problems Social isolation Source Structure Subgroup Survivors Victimization Withdrawal Work analog base burden of illness childhood cancer survivor design disability effective intervention emotional adjustment falls girls improved information processing male peer peer victimization prevent processing speed psychosocial public health relevance radiation effect satisfaction skills skills training social social skills teacher tumor

项目摘要

DESCRIPTION (provided by applicant): Despite the NCI's mission to reduce the burden of cancer on survivors, little progress has been made toward reducing psychosocial morbidity for pediatric brain tumor survivors (PBTS). Social deficits, as well as medical and neuro-cognitive impairment, threaten both their short and long-term quality of life. In our research, classmates have described PBTS as socially withdrawn, victimized and excluded by peers, less liked, and having fewer friends than control classmates. Girls and children treated with radiation have the worst outcomes, but social impairment is not limited to them. These difficulties, particularly as reported by peers, are strongly predictive of emotional, behavioral, and academic difficulties later in life, and PBTS demonstrate more of these deficits as adults than any other subgroup of pediatric cancer survivors. Unfortunately, we lack proven interventions to help these children. Research has yet to identify specific, teachable skills that, when deficient, account for poor social outcomes among PTBS. Social-ecological factors may moderate social outcomes for PTBS and could be targeted by interventions, but have not been examined for this population. Thus, our long- term goal is to reduce morbidity for PBTS by developing tailored interventions for them. The objective of this proposal is to identify the nature and extent of social information processing deficits in PBTS and determine if they, along with social-ecological factors, account for risk for social difficulties. We will recruit 212 PBTS (ages 8-13, >1 year post-treatment) from 3 pediatric hospitals. Mixed methods (i.e., questionnaires, performance- based and analog measures, video-taped interactions with friends) and multiple reporting sources (peer, teacher, mother, father, child) will be used in schools and homes to assess social competence (i.e., social information processing skills, social behavior and interactions, social adjustment) and contextual resources (i.e. parent-child relationship and parenting behavior, friendship quality, and school environment) that account for social competence. Identical data will be obtained for one control classmate per PBTS, matched for gender, race, and age. The rationale is that identifying these factors will allow the selection and design of effective interventions by knowing what to target for which PBTS. Our central hypothesis is that social information processing skills will account for differences in social behavior and adjustment for PBTS, and resources in their families, friendships, and schools will buffer the impact of the tumor and treatment on social competence. The proposed research is significant because it will enable us to develop effective services to minimize long-term morbidity in PTBS.

描述（由申请人提供）：尽管NCI的使命是减轻幸存者的癌症负担，但在降低儿科脑肿瘤幸存者（PBTS）的心理社会发病率方面几乎没有取得进展。社会缺陷以及医学和神经认知障碍都威胁着他们的短期和长期生活质量。在我们的研究中，同学将PBT描述为社会上撤回，受害和排斥的PBT，而不是受欢迎，而不是对照同学的朋友少。接受辐射治疗的女孩和儿童的结果最差，但社会障碍不仅限于他们。这些困难，尤其是同龄人所报道的这些困难，可以很好地预测生活中的情绪，行为和学术困难，而PBT与成年人相比，这些缺陷比其他任何其他小儿科癌症幸存者都更多地证明了这些缺陷。不幸的是，我们缺乏对这些孩子的帮助。研究尚未确定特定的，可教的技能，在不足时，这些技能可以解释PTB中的社会成果不佳。社会生态因素可能会导致PTB的社会成果，并且可以通过干预措施来针对，但尚未对该人群进行检查。因此，我们的长期目标是通过为其开发量身定制的干预措施来降低PBT的发病率。该提议的目的是确定社会信息的性质和程度处理PBT的缺陷，并确定它们是否以及社会生态因素是否会造成社会困难的风险。我们将从 3个儿科医院。混合方法（即，调查表，基于绩效的和模拟措施，与朋友的视频互动）和多个报告资源（同伴，老师，母亲，父亲，父亲，孩子）用于学校和家庭中，以评估社会信息处理能力（社会信息处理技能，社交行为和社交互动，社交互动，社交能力，社交资源）和社交学院和社交教学（即父母之间的关系和父母的关系和父母的关系，友谊和友谊，友谊，友谊，友谊，友谊，友谊，友谊，友谊，友谊，友谊，友谊，友谊，友谊。每个PBT的一个对照同学将获得相同的数据，该数据与性别，种族和年龄相匹配。理由是确定这些因素将允许通过了解有效干预措施选择和设计目标是什么。我们的中心假设是，社会信息处理技能将解释PBT的社会行为和调整的差异，以及其家庭，友谊和学校的资源，将缓解肿瘤和治疗对社会能力的影响。拟议的研究很重要，因为它将使我们能够开发有效的服务，以最大程度地减少PTB中的长期发病率。