Neuroendocrine Investigators and Mentoring in the field of Alcohol Research

酒精研究领域的神经内分泌研究人员和指导

• 批准号: 8730059
• 负责人: GARY S WAND
• 金额: $ 17.26万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8730059
• 关键词: Accounting; Affect; Alcohol dependence; Alcohols; Amphetamines; Animals; Anxiety; Award; Behavior; Brain; Chemicals; Clinical Research; Clinical Trials; Consumption; Data; Data Analyses; Data Collection; Dependency; Development; Doctor of Philosophy; Dopamine; Ethical Issues; Evaluation; Familiarity; Female; Foundations; Functional disorder; Funding; Generations; Glucocorticoids; Goals; Gonadal Steroid Hormones; Health Policy; Hormonal; Human; Human Genetics; Hydrocortisone; Individual; Individual Differences; Informed Consent; Interview; Laboratories; Life; Manuscripts; Measures; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Neurosecretory Systems; Peptides; Performance; Persons; Pharmaceutical Preparations; Positioning Attribute; Positron-Emission Tomography; Preparation; Process; Psyche structure; Relapse; Research; Research Design; Research Personnel; Rewards; Risk; Rodent; Signal Transduction Pathway; Stress; Stress Tests; Substance Use Disorder; Technology; Testing; Testosterone; Training; Training Programs; Universities; Woman; Work; Writing; addiction; alcohol effect; alcohol research; alcohol response; alcohol sensitivity; alcohol use disorder; base; career; cost; design; drug craving; drug of abuse; drug reward; high risk; human subject; interest; knowledge base; male; meetings; men; neurochemistry; neurosteroids; pre-clinical; programs; protocol development; response; skills; stressor; theories; transmission process

DESCRIPTION (provided by applicant): Dr. Wand is a neuroendocrinologist trained in both preclinical and clinical investigation. He works with a multidiscipline team and has acquired hormonal, neurochemical, genetic and human and rodent laboratory skills to pursue his research agenda. Currently Dr. Wand is principle investigator of 4 studies: 2 R01s, 1R03 and a R37 (no cost extension). He is also co- investigator on 6 other R01 awards. Dr. Wand has successfully been the scientific mentor for 16 MD and PhD trainees over the last 12 years. Three of his trainees received K23 awards on their first submission. All 16 trainees are in academics with their own funding or work in health policy positions. Dr. Wand has received awards for mentoring and Johns Hopkins University's highest award for bringing diversity to its training programs. Dr. Wand proposes to initially mentor 5 trainees. He anticipates mentoring approximately 2 additional trainees per year for the life of the award. He participates in multiple programs providing ample opportunities to identify promising trainees to mentor. Dr. Wand's mentoring program is designed to provide animal and human research trainees with a common knowledge base in alcohol theory, research design, data analysis strategies, ethical issues in pre-clinical and clinical research, and grantsmanship skills. In addition, each trainee receives more intensive individual training consistent with his/her special interests. These aspects include hypothesis generation, protocol development, and data analysis. For human investigators he covers human subjects considerations (including the process of obtaining informed consent), subject recruitment, interviewing, data collection, data cleaning, analysis, presentation and manuscript preparation. A primary goal of the mentoring is to enable trainees to develop writing and data analytic skills, as well as familiarity with new research technologies. Each trainee will receive quarterly formal review of goals and progress for performance evaluation and for career guidance. Each trainee meets weekly with one-on-one where he discusses research progress and goes over data, manuscript and reviews/chapters and any other pertinent issues. Individual mentorship provides the foundation for the training program.

描述（由申请人提供）：WAND博士是一名在临床前和临床研究中训练的神经内分泌学家。他与一个多学科团队合作，并获得了荷尔蒙，神经化学，遗传和人类和啮齿动物实验室技能，以追求其研究议程。目前，WAND博士是4项研究的主要研究者：2 R01，1R03和R37（无需延长成本）。他还是其他6个R01奖项的共同研究员。在过去的12年中，Wand博士已成功成为16名MD和博士学位学员的科学导师。他的三名学员在第一次提交时获得了K23奖。所有16名学员都拥有自己的资金或在卫生政策职位上工作的学者。 Wand博士因指导而获得了奖项，约翰·霍普金斯大学（Johns Hopkins University）将多样性带入其培训计划，获得了最高奖项。 Wand博士建议最初指导5名学员。他预计，该奖项的一生每年将指导大约2名受训者。他参加了多个计划，提供了足够的机会来确定有前途的学员为导师。 WAND博士的指导计划旨在为动物和人类研究学员提供酒精理论，研究设计，数据分析策略，临床前和临床研究中的道德问题以及授予技巧的常识基础。此外，每个学员都会接受与他/她的特殊兴趣一致的更深入的个人培训。这些方面包括假设产生，协议开发和数据分析。对于人类研究者，他涵盖了人类受试者的考虑（包括获得知情同意的过程），受试者招聘，访谈，数据收集，数据清洁，分析，演示和手稿准备。指导的主要目标是使学员能够发展写作和数据分析技能，并熟悉新的研究技术。每个学员将获得目标评估和职业指导的目标和进度的季度正式审查。每位受训者每周都会与一对一的一对一开会，在那里他讨论了研究进度，并讨论了数据，手稿和评论/章节以及任何其他相关问题。个人指导为培训计划奠定了基础。