Washington University Intellectual and Developmental Disabilities Research Center

华盛顿大学智力与发育障碍研究中心

基本信息

批准号：
8311712
负责人：
TERRIE E INDER
金额：
$ 85.63万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-08-01 至 2015-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8311712
关键词：
Animal Model Animals Area Biometry Brain Brain imaging Centers of Research Excellence Cerebral Palsy Cerebrum Child Clinical Clinical Research Collaborations Communication Communities Complement Congresses Development Developmental Disabilities Discipline Environment Genetic Goals Growth and Development function Health Human Infant Informatics Intellectual functioning disability Knowledge Learning Mental Retardation Mental Retardation and Developmental Disabilities Research Centers Methods Nature Neurosciences Outcome Patients Philosophy Physicians Prevention Productivity Provider Research Research Activity Research Infrastructure Research Personnel Research Project Grants Research Support Resources Scientist Services Strategic Planning Talents Targeted Research Time Universities Washington base cost effective follow-up improved innovation interdisciplinary collaboration neuroimaging novel novel strategies research facility translational study

项目摘要

DESCRIPTION (Provided by Applicant): The goal of the Washington University Intellectual and Developmental Disabilities Research Center (WUIDDRC) is to promote cutting-edge Innovation to understand and treat intellectual and developmental disabilities. WUIDDRC would provide core resources for 44 outstanding investigators conducting 62 projects related to intellectual and developmental disabilities. WUIDDRC has four main goals: 1. Promote research on developmental disabilities, through new research opportunities, excellence in research facilities, intellectual stimulation, and Interdisciplinary collaborations. WUIDDRC will focus on investigators studying three complementary but fundamentally interrelated research theme areas: cerebral connectivity, genetics, and environmental influences. 2. Provide efficient, cost-effective, state-of-the-art services and facilities to enhance the quality and productivity of WUIDDRC investigators through five cores: Administration, Biostatistics and Informatics, Human Clinical Studies, Brain Imaging, and Animal Model Studies. 3. Create a strong and efficient infrastructure to support research activities related to developmental disabilities. WUIDDRC will attract established and new investigators to add new knowledge and develop innovations impacting IDD. The strategy is to create opportunities for novel collaboration in a large pool of leading research scientists. 4. Build a mechanism for effective, regular, and frequent communication and coordination among WUIDDRC investigators, researchers in other organizations, clinical providers for children with developmental disabilities, and the local community. Washington University in St. Louis has a long record of excellence in neuroscience. But it has gaps in infrastructure to integrate and coordinate research targeted to intellectual and developmental disabilities. WUIDDRC would make existing, sophisticated, and novel approaches readily accessible to its investigators to close these gaps. A practical outcome is to focus local talent on a pressing health problem that offers considerable potential to advance understanding of human brain development. WUIDDRC will stimulate advances by creating a collaborative, interdisciplinary environment that will accelerate research to directly impact children with intellectual and developmental disabilities.

描述（由申请人提供）：华盛顿大学智力和发育障碍研究中心 (WUIDDRC) 的目标是促进尖端创新，以理解和治疗智力和发育障碍。 WUIDDRC 将为 44 名优秀研究人员提供核心资源，开展 62 个与智力和发育障碍相关的项目。 WUIDDRC 有四个主要目标： 1. 通过新的研究机会、卓越的研究设施、智力刺激和跨学科合作，促进对发育障碍的研究。 WUIDDRC 将重点关注研究三个互补但本质上相互关联的研究主题领域的研究人员：大脑连接、遗传学和环境影响。 2. 通过管理、生物统计和信息学、人类临床研究、脑成像和动物模型研究五个核心，提供高效、经济、先进的服务和设施，以提高 WUIDDRC 研究人员的质量和生产力。 3. 创建强大而高效的基础设施来支持与发育障碍相关的研究活动。 WUIDDRC 将吸引现有的和新的研究人员来增加新知识并开发影响 IDD 的创新。该战略是为大量领先研究科学家创造新颖的合作机会。 4. 建立WUIDDRC研究者、其他组织研究人员、发育障碍儿童临床服务提供者和当地社区之间有效、定期、频繁的沟通和协调机制。圣路易斯华盛顿大学在神经科学领域有着悠久的卓越记录。但它在整合和协调针对智力和发育障碍的研究的基础设施方面存在差距。 WUIDDRC 将使其研究人员能够轻松使用现有的、复杂的和新颖的方法来缩小这些差距。一个实际的结果是让当地人才集中研究紧迫的健康问题，该问题为增进对人类大脑发育的理解提供了巨大的潜力。 WUIDDRC 将通过创建一个协作、跨学科的环境来促进进步，从而加速研究，直接影响智力和发育障碍儿童。