Bioinformatics Inquiry through Sequencing (BIOSEQ)

通过测序进行生物信息学查询（BIOSEQ）

• 批准号: 8676956
• 负责人: DAVID R. WALT
• 金额: $ 25.5万
• 依托单位: TUFTS UNIVERSITY MEDFORD
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8676956
• 关键词: Bioinformatics; Biology; Chemistry; Communities; Computers; Data Analyses; Development; Educational process of instructing; Equipment; Faculty; Genetic; Genetic screening method; Genome; Genomics; Goals; Health; High School Faculty; High School Student; Individual; Knowledge; Laboratories; Learning; Medical Research; Medicine; Participant; Play; Process; Public Health; Reagent; Research; Research Proposals; Role; Scholarship; Schools; Science; Students; Testing; Underrepresented Minority; Universities; base; career; college; community college; computer science; design; experience; genome wide association study; graduate student; high school; innovation; low socioeconomic status; microbial; outreach; programs; research study; skills; teacher; tool; undergraduate student; university student

DESCRIPTION (provided by applicant): The overall goal for the Bioinformatics Inquiry through Sequencing (BIOSEQ) project is to provide opportunities for a broad audience of people to learn about the field of bioinformatics through inquiry based research. Three main activities will support this goal: 1. Increase knowledge of and participation in inquiry-based bioinformatics research among students and educators by establishing a sequencing center at Tufts University's Medford Campus for educational use. This sequencing center will be available to college students and high school students through college level research courses and will also be available to educators and students who wish to integrate sequencing into classroom projects, science fair projects, college level theses and graduate level research through an application process. 2. Introduce bioinformatics to college students and high school students through entry level, semester-long research-based courses designed to teach students laboratory skills, computer skills and research skills in the context of student designed projects. The high school student course will happen during the summer session, students will be able to receive college credit. Scholarships will be available for underrepresented minorities and those of low socioeconomic status to participate in the course. 3. Increase teacher knowledge of bioinformatics and inclusion of bioinformatics concepts in their courses by developing modular activities and curricular units to describe bioinformatics concepts, including the impact of bioinformatics on scientific and medical research. Some of these activities and units will be integrated into existing high school biology and computer science courses, and will include understanding of how bioinformatics and genomics have influenced individual and public health through innovations such as Genome Wide Association studies (GWAs) and Direct to Consumer (DTC) genetic testing. This five year project will involve faculty, staff, graduate students, and undergraduate students from Tufts' Chemistry and Computer science departments, faculty and students from Bunker Hill Community College, and teachers and high school students from four diverse, urban partner school districts.

描述（由申请人提供）：通过测序（BIOSEQ）项目进行生物信息学调查的总体目标是为广泛的人提供机会，以通过基于询问的研究来了解生物信息学领域。三个主要活动将支持此目标： 1。通过在塔夫茨大学的梅德福大学校园建立一个测序中心，以增加对学生和教育工作者之间基于询问的生物信息学研究的了解。 该测序中心将通过大学级别的研究课程向大学生和高中生提供，并将为希望通过申请过程将测序纳入课堂项目，科学公平项目，大学级论文和研究生级研究的教育工作者和学生提供。 2。通过入门级，基于学期的研究课程向大学生和高中生介绍生物信息学，旨在在学生设计的项目的背景下教学学生实验室技能，计算机技能和研究技能。 高中学生课程将在夏季课程中进行，学生将能够获得大学学分。奖学金将用于代表性不足的少数群体，而社会经济地位较低的奖学金可以参加该课程。 3。通过开发模块化活动和课程单元来描述生物信息学概念，包括生物信息学对科学和医学研究的影响，提高教师对生物信息学的知识以及在课程中包含生物信息学概念的知识。 其中一些活动和单位将纳入现有的高中生物学和计算机科学课程中，并包括了解生物信息学和基因组学如何通过基因组广泛协会研究（GWAS）等创新影响个人和公共卫生，并直接向消费​​者（DTC）基因测试。 这个五年的项目将参与塔夫茨化学和计算机科学系，邦克山社区学院的教职员工和学生的教职员工，研究生和本科生，以及来自四个不同的城市合作伙伴学区的老师和高中生。