Potassium Level Monitoring System

钾浓度监测系统

基本信息

批准号：
8713146
负责人：
PAUL L GIBSON
金额：
$ 22.43万
依托单位：
ADVANCED MEDICAL ELECTRONICS CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-01 至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8713146
关键词：
Address Affect Algorithms Ambulatory Care Applications Grants Area Arrhythmia Blood Blood Tests Boston Calcium Cardiac Cardiovascular Diseases Cardiovascular system Cessation of life Chemicals Chronic Clinic Clinical Clinical Medicine Clinical Trials Collaborations Communication Computer software Consult Devices Diagnostic Dialysis procedure Disease Diuretics Doctor of Philosophy Echocardiography Economics Elderly Electrocardiogram Electrolytes Electronics Engineering Evaluation FDA approved Fostering Functional disorder Glucose Health Heart Diseases Heart failure Home environment Homeostasis Hospitalization Hospitals Hypokalemia Implant Inborn Genetic Diseases Independent Living Kidney Diseases Kidney Failure Lead Left Magnesium Measurement Measures Medical Medical Electronics Methods Modality Monitor Morbidity - disease rate Operative Surgical Procedures Outpatients Patient Care Patient Monitoring Patients Pharmaceutical Preparations Phase Physicians Physiological Population Potassium Principal Component Analysis Principal Investigator Process Provider Puncture procedure Records Renal Glycosuria Research Research Personnel Risk Running Secondary to Signal Transduction Skin Sodium Specific qualifier value System Technology Telemetry Time To specify Venous blood sampling Virend Visit care delivery design heart rhythm human study improved innovative technologies instrument minimally invasive mortality novel prevent programs prototype public health relevance response sensor signal processing subcutaneous thiazide tool

Address Affect Algorithms Ambulatory Care Applications Grants Area Arrhythmia Blood Blood Tests Boston Calcium Cardiac Cardiovascular Diseases Cardiovascular system Cessation of life Chemicals Chronic Clinic Clinical Clinical Medicine Clinical Trials Collaborations Communication Computer software Consult Devices Diagnostic Dialysis procedure Disease Diuretics Doctor of Philosophy Echocardiography Economics Elderly Electrocardiogram Electrolytes Electronics Engineering Evaluation FDA approved Fostering Functional disorder Glucose Health Heart Diseases Heart failure Home environment Homeostasis Hospitalization Hospitals Hypokalemia Implant Inborn Genetic Diseases Independent Living Kidney Diseases Kidney Failure Lead Left Magnesium Measurement Measures Medical Medical Electronics Methods Modality Monitor Morbidity - disease rate Operative Surgical Procedures Outpatients Patient Care Patient Monitoring Patients Pharmaceutical Preparations Phase Physicians Physiological Population Potassium Principal Component Analysis Principal Investigator Process Provider Puncture procedure Records Renal Glycosuria Research Research Personnel Risk Running Secondary to Signal Transduction Skin Sodium Specific qualifier value System Technology Telemetry Time To specify Venous blood sampling Virend Visit care delivery design heart rhythm human study improved innovative technologies instrument minimally invasive mortality novel prevent programs prototype public health relevance response sensor signal processing subcutaneous thiazide tool

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项目摘要

DESCRIPTION (provided by applicant): Advanced Medical Electronics (AME) and our partners propose a minimally-invasive system for continuous monitoring of potassium. Measurement of blood levels of potassium is important in clinical medicine. Abnormalities of potassium, common in heart and kidney disease, can be aggravated by many medications used to treat these disorders leading to arrhythmias and death. Determination of potassium values has always required access to blood - either by phlebotomy or other skin puncture. The proposed project involves developing a minimally invasive technology that permits determining potassium values without obtaining blood, by recording the body's own response to potassium levels, thereby increasing comfort and convenience for the patient. This technology can be applied in the hospital or at home, extending a remote monitoring platform, and promoting independence and wellness by permitting medication adjustments without hospitalization for frequent blood tests. The ability to manage patients remotely and thereby identify and address health issues early and without need for a clinical visit and blood draw improves care for patients and increases the economic efficiency of care delivery for payors and providers. A prototype system will be developed and evaluated in phase 1.

描述（由申请人提供）：高级医学电子产品（AME）和我们的合作伙伴提出了一个最小侵入性的系统，用于连续监测钾。钾的血液水平的测量在临床医学中很重要。钾的异常（在心脏和肾脏疾病中常见）可能会因用于治疗这些疾病导致心律不齐和死亡的许多药物加剧。钾值的测定始终需要通过静脉切开术或其他皮肤穿刺来获得血液。拟议的项目涉及开发一种微创技术，该技术允许通过记录人体自身对钾水平的反应来确定钾值而不获得血液，从而增加了患者的舒适性和便利性。该技术可以在医院或在家中应用，扩展远程监控平台，并通过允许调整药物调整而无需住院治疗频繁的血液检查，从而促进独立和健康。远程治疗患者，从而尽早识别和解决健康问题的能力，而无需进行临床检查和血液抽血，可以改善患者的护理，并提高付款人和提供者的护理服务的经济效率。将在第1阶段开发和评估原型系统。