MARINE NATURAL PRODUCTS

海洋天然产品

• 批准号: 8361242
• 负责人: TIMOTHY S BUGNI
• 金额: $ 0.3万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361242
• 关键词: Biological Factors; Funding; Goals; Grant; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Sampling; Source; Therapeutic; United States National Institutes of Health; cost; drug discovery; marine natural product; novel; programs

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. In general, this project will focus on marine natural products. In particular, strutures of natural products will be elucidated using primarily NMR. The overarching goal is to isolate novel natural products that have therapeutic potential. Modern drug discovery requires rapid characterization of bioactive hits on small quantities of sample. Therefore, the resources at NMRFAM are invaluable to this program.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 总体而言，该项目将重点关注海洋天然产品。 特别是，天然产物的结构将主要使用核磁共振来阐明。 首要目标是分离具有治疗潜力的新型天然产物。 现代药物发现需要快速表征少量样品的生物活性命中。 因此，NMRFAM 的资源对于该计划来说是无价的。