Diagnostic and prognostic biomarkers for Parkinsons disease

帕金森病的诊断和预后生物标志物

• 批准号: 8742011
• 负责人: RICHARD B DEWEY
• 金额: $ 68.6万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-30 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8742011
• 关键词: Age; Algorithms; Alzheimer' s Disease; Antibodies; Biological; Biological Markers; Blood; Clinical; Clinical Data; Clinical Trials Design; DNA analysis; Diagnosis; Diagnostic; Disease; Disease Progression; Gender; Grant; Libraries; Medical center; Medicine; Movement Disorders; National Institute of Neurological Disorders and Stroke; Parkinson Disease; Participant; Pathology; Patient Care; Patients; Peptoids; Plasma; Policies; Prevalence; Prognostic Marker; Proteins; Public Health; Resources; Sampling; Scanning; Sensitivity and Specificity; Serum; Severity of illness; Specimen; Staging; Visit; base; biobank; data management; forest; medical schools; programs; single photon emission computed tomography

DESCRIPTION (provided by applicant): Biomarkers that can detect PD pathology and that can detect disease progression will be most helpful for patient care and proper clinical trial design. As part of the NINDS Parkinson's Disease Biomarkers Program, we seek to collect biological specimens from PD patients and identify serum biomarkers for disease identification and tracking disease progression.

描述（由申请人提供）：能够检测 PD 病理学和疾病进展的生物标志物将对患者护理和正确的临床试验设计最有帮助。作为 NINDS 帕金森病生物标志物计划的一部分，我们寻求从帕金森病患者收集生物样本并鉴定血清生物标志物，以用于疾病识别和跟踪疾病进展。