Adaptive Interventions for Problem Drinkers

针对饮酒问题的适应性干预措施

基本信息

批准号：
9649148
负责人：
JON MORGENSTERN
金额：
$ 60.02万
依托单位：
FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-03-10 至 2022-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9649148
关键词：
Adaptive Behaviors Adoption Aftercare Alcohol abuse Algorithms American Behavior Therapy Caring Chronic Disease Complex Coping Skills Data Development Ecological momentary assessment Empirical Research Engineering Evidence based treatment Feedback Fostering Future Goals Healthcare Impulsivity Individual Informal Social Control Intervention Intervention Studies Knowledge Mainstreaming Mathematics Mediating Mediation Methodology Methods Modeling Outcome Participant Pathway interactions Pattern Persons Process Protocols documentation Randomized Regimen Selection for Treatments Self-control as a personality trait Sequential Multiple Assignment Randomized Trial Severities Statistical Methods Suggestion Testing Time Treatment Step adaptive intervention alcohol cue alcohol exposure alcohol seeking behavior alcohol use disorder brief advice brief intervention craving drinking effective therapy engineering design experience health care settings improved mathematical model medical specialties method development motivational enhancement therapy novel novel strategies problem drinker psychosocial public health priorities public health relevance recruit response sensor technology simulation skills support tools theories therapy development tool trait treatment research treatment response

项目摘要

DESCRIPTION (provided by applicant): Problem drinkers (PDs) represent a majority of the estimated 32 million Americans with alcohol problems that spans a spectrum of severity from individuals who drink excessively and experience of occasional negative consequences to those with moderate AD and intact psychosocial functioning. PDs can benefit from relatively brief treatment that could be delivered in mainstream healthcare, but less than 5% receive such care. In addition, PD treatment is only modestly effective, and there is a surprising absence of empirical research to guide PD treatment selection. Adaptive Interventions (AI) are a novel approach to treatment development that may have significant advantages over fixed treatments in improving efficacy and fostering adoption of EBPs in mainstream healthcare. Over the last decade, important advances have been made in AI development methods including Sequential Multiple Assignment Randomized Trials (SMART) and control engineering (CE) designs. These advances have yielded important discoveries in the treatment of other chronic illnesses but are just beginning to be applied to AUD. This study proposes to combine SMART, CE, and ecological momentary assessment to develop an AI for PD that can be used in mainstream healthcare. If study aims are achieved, a set of empirically-derived decision support tools will be created to guide AUD care similar to tools that exist for other chronic diseases. In addition, new knowledge will be gained about MOBC of AUD that can guide future AUD treatment research. Finally, important progress will be made in methods that capitalize on the remarkable advances in sensor technologies, advanced mathematics, and engineering to create a new type of tailored, near-real time feedback, adaptive behavior therapies

描述（由申请人提供）：问题饮酒者（PDS）代表了估计有3200万美国人的酒精问题的大多数，这些人的严重程度涵盖了过度喝酒的人，并且对中度AD和完整的心理社会功能的人偶尔会产生负面影响。 PD可以从相对简短的治疗中受益，该治疗可以在主流医疗保健中提供，但不到5％的人获得了这种护理。此外，PD治疗仅适度有效，并且缺少实证研究来指导PD治疗选择。自适应干预措施（AI）是一种新型的治疗开发方法，在提高疗效和促进主流医疗保健中EBP的采用方面可能具有显着优势。在过去的十年中，在AI开发方法中取得了重要的进步，包括顺序多个分配随机试验（SMART）和控制工程设计（CE）设计。这些进步在治疗其他慢性疾病时产生了重要的发现，但刚刚开始应用于AUD。这项研究建议将智能，CE和生态瞬时评估相结合，以开发可用于主流医疗保健的PD的AI。如果实现了学习目标，一组经验衍生的决策支持工具将是创建的是指导AUD护理，类似于其他慢性疾病的工具。此外，将获得有关AUD MOBC的新知识，该知识可以指导未来的AUD治疗研究。最后，将利用传感器技术，高级数学和工程学的显着进步的方法来取得重要的进步

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A Comparison of Mathematical and Statistical Modeling with Longitudinal Data: An Application to Ecological Momentary Assessment of Behavior Change in Individuals with Alcohol Use Disorder.

数学和统计模型与纵向数据的比较：酒精使用障碍个体行为变化的生态瞬时评估的应用。

DOI：
10.1007/s11538-022-01097-1
发表时间：
2022
期刊：
Bulletin of mathematical biology
影响因子：
3.5
作者：
Shao,Sijing;Canner,JudithE;Everett,RebeccaA;Bekele-Maxwell,Kidist;Kuerbis,Alexis;Stephenson,Lyric;Menda,Jennifer;Morgenstern,Jon;Banks,HT
通讯作者：
Banks,HT

Optimal design for dynamical modeling of pest populations.

害虫种群动态建模的优化设计。