Third International Conference on Cardiomyopathy in Children

第三届国际儿童心肌病会议

• 批准号: 8719524
• 负责人: STEVEN EDWARD LIPSHULTZ
• 金额: $ 1万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8719524
• 关键词: Affect; Age; Age-Years; Area; Basic Science; Cardiomyopathies; Caring; Child; Child health care; Childhood; Clinical; Clinical Research; Clinical Treatment; Communication; Data; Development; Diagnosis; Diagnostic; Disease; Educational workshop; Epidemiologist; Epidemiology; Etiology; Family; Foundations; Funding; Future; Genetic; Goals; Healthy People 2020; Heart Transplantation; Heart failure; Incidence; Individual; Industry; Infant Health; International; Intervention; Knowledge; Lead; Life Expectancy; Literature; Lymphoma; Malignant Childhood Neoplasm; Maternal Health; Medical; Modeling; Molecular; Molecular Genetics; Myocarditis; Myocardium; National Heart, Lung, and Blood Institute; Nephroblastoma; Neuroblastoma; Online Systems; Outcome; Patients; Population; Prevention; Prevention strategy; Primary Myocardial Diseases; Publications; Publishing; Quality of life; Recommendation; Registries; Research; Scientist; Shapes; Transplantation; career; design; improved; knowledge base; meetings; multidisciplinary; new technology; novel; novel strategies; public health relevance; success; symposium

DESCRIPTION (provided by applicant): Cardiomyopathy is a serious disease of the heart muscle. Nearly 40 percent of children with cardiomyopathy receive a heart transplant or die within the first 2 years after diagnosis. The percentage of children with cardiomyopathy who received a heart transplant has not declined over the past 10 years and cardiomyopathy remains the leading cause of transplantation for children over one year of age. Studies from the National Heart, Lung, and Blood Institute (NHLBI)-funded Pediatric Cardiomyopathy Registry (PCMR) have shown that the cause of cardiomyopathy is established in very few children yet genetic causes are likely to be present in most. The incidence of pediatric cardiomyopathy is approximately 1 per 100,000 children. This is comparable to the incidence of such childhood cancers such as lymphoma, Wilms' tumor, and neuroblastoma. However, the published research and scientific conferences focused on pediatric cardiomyopathy is much less than for these other conditions. The purpose of the proposed conference, the Third International Conference on Cardiomyopathy in Children is to build on the success of the first conference, "Idiopathic and Primary Cardiomyopathy in Children- Research Directions and Strategies" held in 2007 (cosponsored by NHLBI and the Children's Cardiomyopathy Foundation), and the Second International Conference on Cardiomyopathy in Children held in 2010 (cosponsored by the Children's Cardiomyopathy Foundation and the Myocarditis Foundation with additional funding from the NHLBI-sponsored Pediatric Cardiomyopathy Registry) to review the current knowledge base from research on cardiomyopathy including research areas not covered in the first and second conferences. This meeting is designed to bring together a multidisciplinary group of scientists (entry-level, mid-career, and senior), including molecular biologists, epidemiologists and clinicians in order to disseminate the most up to date research on the prevention, etiology, diagnosis, mechanisms, and treatment of pediatric cardiomyopathy and to shape the direction of future research on the disease. It is anticipated that this interdisciplinar exchange of knowledge will identify data gaps and needs, future research directions and new approaches and technologies that will lead to a better understanding of this disease and improved intervention and prevention strategies.

描述（由申请人提供）：心肌病是心肌的严重疾病。诊断后的头两年内，近40％的心肌病儿童接受心脏移植或死亡。在过去的10年中，接受心脏移植的心肌病儿童的百分比没有下降，心肌病仍然是一岁以上儿童移植的主要原因。国家心脏，肺和血液研究所（NHLBI）资助的小儿心肌病登记册（PCMR）的研究表明，在很少的儿童中建立了心肌病的原因，但大多数儿童可能会出现遗传原因。小儿心肌病的发病率约为每10万儿童1。这与淋巴瘤，Wilms肿瘤和神经母细胞瘤等儿童期癌症的发生率相当。但是，针对儿科心肌病的发表的研究和科学会议远低于其他疾病。 The purpose of the proposed conference, the Third International Conference on Cardiomyopathy in Children is to build on the success of the first conference, "Idiopathic and Primary Cardiomyopathy in Children- Research Directions and Strategies" held in 2007 (cosponsored by NHLBI and the Children's Cardiomyopathy Foundation), and the Second International Conference on Cardiomyopathy in Children held in 2010 (cosponsored by the Children's Cardiomyopathy Foundation and心肌炎基金会通过NHLBI赞助的儿科心肌病登记册获得了额外的资金，以审查当前对心肌病的研究的知识库，包括第一和第二会议中未涵盖的研究领域。这次会议旨在汇集一个多学科的科学家（入门级，中级和高级），包括分子生物学家，流行病学家和临床医生，以消除有关预防，病因，病因，诊断，机制，机制和治疗的最新研究。可以预料，这种跨学科的知识交流将确定数据差距和需求，未来的研究方向以及新的方法和技术，这些方法和技术将更好地理解这种疾病，并改善了干预和预防策略。