Direct catalytic C-C coupling via transfer hydrogenation

通过转移氢化直接催化 C-C 偶联

• 批准号: 8652109
• 负责人: Brannon Sam
• 金额: $ 3.63万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-01-22 至 2015-01-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8652109
• 关键词: Alcohols; Aldehydes; Amines; Biological Factors; Catalysis; Chemistry; Complex; Coupling; Data; Development; FDA approved; Funding; Funding Opportunities; Generations; Goals; Hydrogenation; Investigation; Iridium; Laboratories; Metals; Methods; Organic Chemistry; Organic Synthesis; Oxidation-Reduction; Process; Reagent; Reporting; Research; Research Training; Ruthenium; Scheme; Students; Techniques; Therapeutic Agents; Training; Training Programs; Transition Elements; catalyst; dehydrogenation; improved; oxidation; public health relevance; skills; small molecule

DESCRIPTION (provided by applicant): The main objective of the proposed funding period is to train Mr. Brannon Sam, such that he is competitive in the field of organic chemistry at the highest national level. Undertaking such a challenge as the proposed project in catalytic C-C bond formation of amines and unsaturates allows for the development of the skills needed to advance modern chemistry, particularly in regards to complex molecules synthesis. The proposed project will promote Brannon's autonomy by improving his abilities to think critically, interpret and present data, and employ organic synthesis technique. He will gain a deeper understanding of transition-metal catalysis and small-molecule synthesis. Brannon will be the only student trained under this funding opportunity, and there will be approximately 20 students in the laboratory that he will interact with.

描述（由申请人提供）：拟议资助期的主要目标是培训 Brannon Sam 先生，使他在有机化学领域具有国家最高水平的竞争力。接受胺和不饱和化合物催化 C-C 键形成的拟议项目这样的挑战，可以发展推进现代化学所需的技能，特别是在复杂分子合成方面。拟议的项目将通过提高布兰农批判性思考、解释和呈现数据以及运用有机合成技术的能力来促进布兰农的自主性。他将对过渡金属催化和小分子合成有更深入的了解。布兰农将是唯一在此资助机会下接受培训的学生，他将与实验室中大约 20 名学生进行互动。