Beliefs and decision-making about HPV vaccination among young men who have sex wi

有性行为的年轻男性对 HPV 疫苗接种的信念和决策

• 批准号: 8653421
• 负责人: Christopher W. Wheldon
• 金额: $ 3.3万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8653421
• 关键词: Address; Adolescent; Adult; Advisory Committees; Affect; Age; Anal Intraepithelial Neoplasia; Anal canal; Anogenital venereal warts; Anus; Attention; Attitude; Behavior; Behavioral Research; Belief; Biological; Centers for Disease Control and Prevention (U.S.); Characteristics; Child; Communities; Decision Making; Disease; Educational Intervention; Empirical Research; Ensure; Etiology; Female; Gardasil; Goals; HIV; HIV Seropositivity; Health Educators; Health education; Heterosexuals; Human Papilloma Virus Vaccination; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papilloma virus infection; Human papillomavirus 16; Immunization; Incidence; Infection; Infection prevention; Intervention; Interview; Investigation; Knowledge; Language; Lead; Lesbian Gay Bisexual Transgender; Link; Malignant Neoplasms; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Measures; Mentorship; Methods; Modeling; Oncogenic; Outcome; Outcomes Research; Perception; Phase; Population; Population Study; Prevalence Study; Prevention; Public Health; Qualitative Methods; Research; Risk; Sexually Transmitted Diseases; Source; Squamous intraepithelial lesion; Structure; Subgroup; Surveys; Time; Training; Trust; United States Food and Drug Administration; Vaccination; Vaccines; Woman; aged; base; behavior prediction; cancer epidemiology; disorder prevention; health disparity; high risk; innovation; male; men; men who have sex with men; prevent; programs; prophylactic; public health relevance; racial and ethnic; screening; sex; skills; social; theories; uptake; young man

DESCRIPTION (provided by applicant): Men who have sex with men (MSM) are at increased risk of anal cancer as a result of prevalent anal human papillomavirus (HPV) infection in this population. Prophylactic vaccination is a potentially effective public health strategy for preventing anal cancer. A quadrivalent vaccine is currently approved for the prevention of anal cancer and anal squamous intraepithelial lesions in both males and females. As a result, routine vaccination is recommended for all MSM up through at 26. Maximizing vaccine uptake among populations of MSM will require public health interventions to address factors influencing vaccine acceptability, intentions, and subsequent behavior. Currently, public health educators have limited information available to effectively tailor health education messages and interventions aimed at increasing HPV vaccine uptake among vaccine-eligible adult MSM. The Integrative Model of Behavioral Prediction (IM) is a viable theoretical framework from which to understand HPV vaccine decision-making and to guide social and culturally tailored interventions. According to this model, health education interventions must address the salient HPV-related beliefs and perceptions expressed by young MSM in order to effectively promote vaccination. The long-term goal of this research is to decrease the incidence of anal cancer among MSM by preventing infection of HPV types -16 and -18 through vaccination. The purpose of the proposed research is to understand the factors important to young MSM when making decisions about HPV vaccination by addressing the following specific aims: (1a) Describe salient outcome, normative, and control beliefs related to HPV vaccination among young MSM; (1b) determine factors that underlie these beliefs through semi-structured qualitative interviews and a structured open-ended qualitative survey; (2) explore the influence of socio-demographic characteristics, such as age and racial/ethnic background, in HPV vaccine decision-making among young MSM; and (3) identify information needs and trusted sources of information regarding HPV vaccination among young MSM. These objectives will be addressed in a multi-method sequential qualitative study including semi-structured interviews (Phase 1) and an open-ended qualitative survey (Phase 2) of MSM 18 to 26 years old. The proposed research will reinforce the applicants training plan in cancer epidemiology, the public health needs of lesbian, gay, bisexual and transgender populations, and the use of qualitative methods in health education research. Through a combination of coursework, directed study, and mentorship from his sponsorship team, the proposed training plan will ensure that the applicant will obtain the level of knowledge and skills necessary to build a program of research that will address the critical public health needs of LGBT populations.

描述（由申请人提供）： 男男性行为者 (MSM) 由于肛门人乳头瘤病毒 (HPV) 感染在该人群中普遍存在，因此患肛门癌的风险增加。预防性疫苗接种是预防肛门癌的一种潜在有效的公共卫生策略。目前批准四价疫苗用于预防男性和女性的肛门癌和肛门鳞状上皮内病变。因此，建议所有 MSM 到 26 岁都进行常规疫苗接种。要最大限度地提高 MSM 人群的疫苗接种率，需要采取公共卫生干预措施，以解决影响疫苗可接受性、意图和后续行为的因素。目前，公共卫生教育者可用的信息有限，无法有效定制健康教育信息和干预措施，以提高符合疫苗资格的成年 MSM 的 HPV 疫苗接种率。行为预测综合模型 (IM) 是一个可行的理论框架，可用于了解 HPV 疫苗决策并指导社会和文化定制干预措施。根据该模型，健康教育干预措施必须解决年轻 MSM 所表达的与 HPV 相关的显着信念和认知，才能有效促进疫苗接种。这项研究的长期目标是通过疫苗接种预防 HPV -16 和 -18 型感染，从而降低 MSM 中肛门癌的发病率。拟议研究的目的是通过解决以下具体目标，了解年轻 MSM 在做出 HPV 疫苗接种决策时重要的因素： (1a) 描述年轻 MSM 中与 HPV 疫苗接种相关的显着结果、规范和控制信念； (1b) 通过半结构化定性访谈和结构化开放式定性调查确定这些信念背后的因素； (2) 探讨年龄和种族/族裔背景等社会人口特征对年轻 MSM HPV 疫苗决策的影响； (3) 确定年轻 MSM 中有关 HPV 疫苗接种的信息需求和可信信息来源。这些目标将通过多方法序贯定性研究来实现，包括针对 18 至 26 岁 MSM 的半结构化访谈（第一阶段）和开放式定性调查（第二阶段）。拟议的研究将加强申请人在癌症流行病学、女同性恋、男同性恋、双性恋和跨性别人群的公共卫生需求以及健康教育研究中定性方法的使用方面的培训计划。通过结合课程作业、定向学习和赞助团队的指导，拟议的培训计划将确保申请人获得建立解决 LGBT 关键公共卫生需求的研究计划所需的知识和技能水平人口。

项目成果

An Assessment of Cancer Education Needs to Promote Mid-Adult HPV Vaccination Among Male Sexual Minorities.

癌症教育评估需要促进男性性少数人群中成人 HPV 疫苗接种。

• DOI: 10.1007/s13187-019-01644-w
• 发表时间: 2021
• 期刊: Journal of cancer education : the official journal of the American Association for Cancer Education
• 作者: Wheldon,ChristopherW;Maness,SarahB
• 通讯作者: Maness,SarahB