North Carolina Translational & Clinical Sciences Institute (NC TraCS)

北卡罗来纳州翻译

• 批准号: 8917646
• 负责人: MARSCHALL S. RUNGE
• 金额: $ 11.34万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-26 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8917646
• 关键词: Address; Area; Award; Basic Science; Biomedical Research; Clinical; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Commit; Communities; Data; Discipline; Discipline of Nursing; Disease; Elements; Ensure; Evaluation; Evolution; Faculty; Foundations; Fruit; Funding; Future; Generations; Goals; Health; Health Policy; Health Sciences; Home environment; Human; Institutes; Institution; Interdisciplinary Study; International; Leadership; Measures; Medicine; Mentors; Methods; Metric; Nature; North Carolina; Patient Care; Patients; Pharmacy facility; Pilot Projects; Policies; Positioning Attribute; Process; Public Health; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Safety; School Dentistry; Science; Services; Technology; Testing; Time; Training; Training Support; Translational Research; U-Series Cooperative Agreements; Universities; Work; authority; c new; career; career development; catalyst; clinical application; clinical practice; comparative effectiveness; drug development; effectiveness research; expectation; experience; improved; innovation; meetings; next generation; novel; programs; research and development; research study; success; tool

Five years after its formation, the Clinical and Translational Science Award (CTSA) at the Univeristy of North Carolina at Chapel Hill (UNC), the North Carolina Translational and Clinical Sciences Institute (NC TraCS), has become the integrated, campus-wide home for clinical and translational research at UNC. The overall goal of this U54 Cooperative Agreement application is to combine the research strengths, resources and opportunities at UNC and new partner, RTI International (RTI), to build on the foundation established in the CTSA's last five years. NC TraCS .will work to improve human health by accelerating clinical and translational research from health science discovery to dissemination to patients and communities. NC TraCS will strive to overcome the well-documented barriers to the effective, sustained translation of research discovery along the translational research continuum by improving efficiency, training a research workforce and exporting successful, validated methods developed in NC TraCS to other CTSA institutions and the public. The proposed CTSA will specifically (1) amplify a thriving CTSA program to the point that it supports the full spectrum of clinical and translational research; (2) leverage CTSA resources and institutional strengths to create a critical, sustained focus on three strategic initiatives: (a) next-generation technologies to transform the very nature of clinical research and practice, (b) new paradigms and resources to accelerate drug development, and (c) robust comparative effectiveness research studies to provide definitive evidence of the benefits and harms of tests and treatments; and (3) train, support and incentivize the next generation of clinical and translational science researchers. These goals will be accomplished by three resources, six services, integrated and streamlined from the original 11, and the three strategic initiatives. UNC and RTI now have a unique set of research and training resources to support the full range of clinical and translational research, from basic science to clinical application to policy change. NC TraCS will leverage the opportunity of this CTSA application to garner >$60 million dollars in matching institutional support to extend our capabilities to meet the three aims. In partnership with RTI, NC TraCS will take advantage of the resources it has created and nourished during the past five years to quickly and effectively bring the fruits of research to patients across the state, as well as nationally through the CTSA Consortium.

成立五年后，North Univerristy的临床和转化科学奖（CTSA） 北卡罗来纳州翻译和临床科学研究所（NC TRACS）的CARPEL HILL（UNC）的Carolina， 已成为UNC的综合校园范围内的临床和转化研究之家。总体 该U54合作协议申请的目标是结合研究优势，资源和 UNC和新合作伙伴RTI International（RTI）的机会，建立在建立的基础之上 CTSA的最后五年。 NC Tracs。将通过加速临床和 从健康科学发现到传播到患者和社区的转化研究。 NC TRAC将努力克服有效，持续的研究翻译的有据可查的障碍 通过提高效率，培训研究人员，沿转化研究连续性发现 并向NC TRAC开发的成功，经过验证的方法向其他CTSA机构和 民众。拟议的CTSA将专门（1）扩大繁荣的CTSA程序，以至于它支持 临床和转化研究的全部范围； （2）利用CTSA资源和机构 在三个战略举措上建立关键，持续关注的优势：（a）下一代技术 为了改变临床研究和实践的本质，（b）新的范式和资源以加速 药物开发，以及（c）强大的比较有效性研究以提供明确的证据 测试和治疗的益处和危害； （3）训练，支持和激励下一代 临床和转化科学研究人员。这些目标将通过三个资源，六个来实现 服务，从原始11和三个战略计划中进行了整合和简化。 UNC和RTI现在拥有一套独特的研究和培训资源，以支持一系列 临床和转化研究，从基础科学到临床应用再到政策变化。 NC Tracs会 利用此CTSA申请的机会来获得> 6000万美元的匹配机构 支持我们的能力达到三个目标。与RTI合作，NC TRAC将采用 它在过去五年中创造和滋养的资源的优势，可以快速有效地 通过CTSA财团将研究成果带给全州以及全国范围内的患者。