Core A: Administration and Biostatistics

核心 A：管理和生物统计学

• 批准号: 8742036
• 负责人: Patrick Lee Green
• 金额: $ 18.76万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-23 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8742036
• 关键词: Accounting; Affect; Biocompatible Materials; Biometry; Biostatistics Core; Budgets; Cancer Model; Clinical; Collaborations; Communication; Coordination and Collaboration; Data; Data Display; Data Set; Databases; Development; Drug Formulations; Effectiveness; Ensure; Evaluation; Expenditure; Experimental Designs; Glean; Goals; Grant; Institution; Investigation; Laboratories; Manuscripts; Monitor; Outcome; Participant; Preparation; Procedures; Program Effectiveness; Program Evaluation; Publications; Reagent; Reporting; Research; Research Design; Research Personnel; Resolution; Resources; Retroviridae; Retrovirology; Scientist; Secure; Services; Standardization; Statistical Data Interpretation; Time; abstracting; animal tissue; base; data integration; data integrity; data management; data sharing; design; meetings; member; model design; operation; posters; programs; quality assurance; research study; statistics; tissue culture; web site

PROJECT SUMMARY The Administration and Biostatistics Core will provide centralized grant administration, communications, data sharing, and statistical analyses for the projects. This Core also serves to amalgamate the investigators, their experimental findings and their ideas, promote translational efforts and direct efforts toward the Program goals and outcomes. In addition, the Biostatistics and Data Integration part of this core will create and operate a secure web site for the interchange of data, communications, and the evaluation of Program progress. Specific Aims include: Aim 1. Provide basic administrative services to the investigators. ¿ Service includes the management of supplies, filing, development of memos, meeting minutes and communications covering all operations. The Core will provide investigators with clear lines of scientific and administrative communication to promote collaboration, aid in the prioritization of resources, and facilitate resolution of any problems that affect team members. ¿ Provide publication services to the investigators for project-related communications. Aim 2. Provide data management and statistical analyses for all projects. ¿ To collaborate with project investigators in the formulation of hypotheses and study design. ¿ To conduct and direct the statistical analysis of data including both descriptive summary statistics and sophisticated inferential procedures. ¿ Provide timely review, quality assurance, and dissemination of the results gleaned from investigations. ¿ To install data prioritization evaluation and an inter-institutional secure website for sharing and storing databases. Provide access in real-time to data sets and standardization of data sets to permit data managers from all institutions to have input on statistics and direct modeling and experimental design. Aim 3. Organize Scientific and Advisory Board Meetings ¿ Monthly Steering Committee Meetings (Project Leaders, Core Directors, and key staff members). ¿ Weekly PPG Retrovirology Laboratory Scientific Data Meetings (all project members and their labs) ¿ Annual Internal and External Scientific Advisory Board (ISAB & ESAB) meetings. Panel of experts shall assess the Program effectiveness and experimental progress, research directions, statistical evaluation, and admin effectiveness. Each board will review experimental findings and translational outcomes, help prioritize investigations, review collaborations, and evaluate concepts that emerge. Aim 4. Provide overall fiscal review, accounting, and real time budgets analyses.

项目概要 行政和生物统计核心将提供集中拨款管理、通信、数据 该核心还有助于合并研究人员及其研究人员。 实验结果及其想法，促进转化努力并直接努力实现计划目标 此外，该核心的生物统计和数据集成部分将创建并运营一个 用于交换数据、通信和评估计划具体进展的安全网站。 目标包括： 目标 1. 为调查人员提供基本的行政服务。 ¿服务包括管理用品、归档、制定备忘录、会议纪要和 覆盖所有行动的通信将为调查人员提供清晰的科学和信息线索。 行政沟通，以促进合作，帮助确定资源的优先顺序，并促进 解决影响团队成员的任何问题。 ¿为研究人员提供与项目相关的交流的出版服务。 目标2.为所有项目提供数据管理和统计分析。 ¿与项目研究人员合作制定假设和研究设计。 ¿进行和指导数据统计分析，包括描述性汇总统计和 复杂的推理过程。 ¿及时审查、质量保证并传播调查结果。 ¿安装数据优先级评估和机构间安全网站以进行共享和存储 提供对数据集的实时访问和数据集的标准化以允许数据。 所有机构的管理人员都可以参与统计、直接建模和实验设计。 目标 3. 组织科学和顾问委员会会议 ¿每月指导委员会会议（项目负责人、核心董事和主要工作人员）。 ¿每周 PPG 逆转录病毒学实验室科学数据会议（所有项目成员及其实验室） ¿年度内部和外部科学顾问委员会（ISAB 和 ESAB）专家小组会议。 应评估计划的有效性和实验进展、研究方向、统计 每个委员会将审查实验结果和转化。 结果，帮助确定调查的优先顺序，审查合作并评估出现的概念。 目标 4. 提供总体财务审查、会计和实时预算分析。