Translation of a Lung Cancer Palliative Care Intervention for Clinical Practice

肺癌姑息治疗干预措施在临床实践中的转化

• 批准号: 8824711
• 负责人: BETTY R FERRELL
• 金额: $ 62.54万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-28 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8824711
• 关键词: Accident and Emergency department; Accounting; Address; Admission activity; Area; Behavioral Research; Cancer Patient; Cancer Science; Caregiver Burden; Caregivers; Caring; Cause of Death; Cities; Collaborations; Data; Data Analyses; Decision Making; Development; Dietitian; Disease; Distress; Educational process of instructing; Elements; Family Caregiver; Funding; Gender; Hospitals; Intervention; Life; Link; Malignant Neoplasms; Malignant neoplasm of lung; Modeling; Monitor; Non-Small-Cell Lung Carcinoma; Outcome; Palliative Care; Patient Care Planning; Patients; Personal Satisfaction; Preparation; Psychologist; Psychosocial Assessment and Care; Quality of life; Quality-of-Life Assessment; Research; Resources; Services; Site; Social Work; Staging; Supportive care; Symptoms; System; Testing; Translations; United States; Visit; cancer care; cancer palliative treatment; caregiver education; caregiving; chemotherapy; clinical practice; data management; end of life; group intervention; hospice environment; improved; oncology; programs; psychologic; psychological distress; public health relevance; skills; statistics; symptom management; treatment as usual; urgent care

DESCRIPTION (provided by applicant): Lung cancer is the second most common cancer in the United States, accounting for 55% of all new cancer cases. It is the second leading cause of all new cancer cases but the first leading cause of death across genders. In cases where curative intent is not an option, and advanced stages at presentation is common, palliative care becomes an important aspect of care for lung cancer patients. An interdisciplinary palliative care model can effectively link lung cancer patients to the appropriate supportive care services in a timely fashion. Family caregivers (FCG) are also centrally involved in the care of lung cancer patients, assuming primary responsibility for supporting patients across the trajectory of disease. The purpose of this study is to test the dissemination of a Palliative Care Intervention (PCI) for patients with non-small cell lung cancer (NSCLC) and their primary FCG. The PCI was developed and tested in a Program Project (P01) conducted at the City of Hope in approximately 400 lung cancer patients and 350 FCGs. The dissemination plan will be guided by the RE-AIM model. Our specific aims include the adaptation of the intervention from the P01 into three Palliative Care Research Cooperative Group (PCRC) sites, and testing the impact of the intervention on patient and FCG outcomes. We hypothesize that the PCI intervention will improve QOL, symptoms, and distress for patients, and improve burden, distress, and QOL for FCGs. The PCI Intervention consists of several components, and includes a comprehensive QOL assessment of patient and FCG needs, development of palliative care plan with an interdisciplinary team, and patient and FCG teaching sessions. This application has been developed in collaboration with the PCRC, with data management and analysis to be conducted at the PCRC Data and Statistics Center. It addresses the three broad areas identified by the NINR in the RFA including: 1) Bio behavioral research; 2) The impact of transitions along the palliative care spectrum; and 3) Caregiving issues.

描述（由申请人提供）：肺癌是美国第二大常见癌症，占所有新发癌症病例的 55%。它是所有新癌症病例的第二大原因，但却是跨性别死亡的第一大原因。在无法选择治愈目的且就诊时已处于晚期的情况下，姑息治疗成为肺癌患者护理的一个重要方面。跨学科姑息治疗模式可以有效地将肺癌患者及时与适当的支持性护理服务联系起来。家庭护理人员 (FCG) 也主要参与肺癌患者的护理，承担支持患者度过疾病轨迹的主要责任。本研究的目的是测试姑息治疗干预 (PCI) 对非小细胞肺癌 (NSCLC) 及其原发性 FCG 患者的传播情况。 PCI 是在希望之城开展的一项计划项目 (P01) 中开发并在大约 400 名肺癌患者和 350 个 FCG 中进行测试的。传播计划将以 RE-AIM 模型为指导。我们的具体目标包括将 P01 的干预措施调整到三个姑息治疗研究合作组 (PCRC) 站点，并测试干预措施对患者和 FCG 结果的影响。我们假设 PCI 干预将改善患者的生活质量、症状和痛苦，并改善 FCG 的负担、痛苦和生活质量。 PCI 干预由多个部分组成，包括对患者和 FCG 需求的全面 QOL 评估、与跨学科团队一起制定姑息治疗计划以及患者和 FCG 教学课程。该应用程序是与PCRC合作开发的，数据管理和分析将在PCRC数据和统计中心进行。它涉及 NINR 在 RFA 中确定的三大领域，包括：1) 生物行为研究； 2) 姑息治疗领域转型的影响； 3) 护理问题。