Engineering Core

工程核心

• 批准号: 8400564
• 负责人: Eric Daniel Young
• 金额: $ 33.61万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-23 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8400564
• 关键词: Algorithms; Amplifiers; Animal Model; Animals; Archives; Behavior Control; Behavioral; Brain; Calcium; Complex; Computer software; Computers; Computing Methodologies; Data; Data Analyses; Databases; Development; Disease; Electrodes; Electronics; Engineering; Environment; Equilibrium; Equipment; Event; Faculty; Hearing; Imagery; Information Theory; Laboratories; Methods; Modeling; Modification; Nervous system structure; Neurons; Occupations; Population; Power Sources; Process; Protocols documentation; Psychophysiology; Research; Research Personnel; Services; Stimulus; System; Systems Theory; Techniques; Technology; Temperature; Time; Training; Unmarried person; Work; Writing; analytical method; awake; behavior test; computer program; computerized data processing; data acquisition; design and construction; imaging modality; innovation; new technology; programs; relating to nervous system; repaired; research study; sensory mechanism; software development; software systems; technology development

A rate-limiting step for many studies of the nervous system is obtaining and effectively using the sophisticated technical hardware and analytical methods needed for innovative research. These constraints apply as well to studies of neural signal processing in the brain as they do to studies of disordered processing in animal models of hearing or balance deficits. Even if hardware/software systems are available for planned experiments, they inevitably require modification for special purposes or integration with other systems in the laboratory. This Engineering Core aims to solve these electronics and computer problems by providing computer programming and electronics expertise to researchers in the Center for Hearing and Balance. The cumulative expertise of our staff makes it possible for our research faculty to focus on experiments and not technology development and allows rapid progress in the use of new technologies. During the past five years this core has developed new behavioral interfaces, new telemetric recording equipment for use in awake and unrestrained animals, and new software for on-line optimization of neuron models. We have adapted multi-single unit recording techniques for our uses and have provided support for routine problems of technology usage.

许多神经系统研究的限速步骤是获取并有效使用创新研究所需的复杂技术硬件和分析方法。这些限制同样适用于大脑神经信号处理的研究，也适用于听力或平衡缺陷动物模型中无序处理的研究。即使硬件/软件系统可用于计划的实验，它们也不可避免地需要出于特殊目的进行修改或与实验室中的其他系统集成。该工程核心旨在通过向听力与平衡中心的研究人员提供计算机编程和电子专业知识来解决这些电子和计算机问题。我们员工积累的专业知识使我们的研究人员能够专注于实验而不是技术开发，并在新技术的使用方面取得快速进展。在过去五年中，该核心开发了新的行为界面、用于清醒和不受约束的动物的新遥测记录设备，以及用于神经元模型在线优化的新软件。我们根据我们的用途采用了多单元记录技术，并为技术使用的常规问题提供了支持。