2012 Synaptic Transmission Gordon Research Conference

2012年突触传递戈登研究会议

• 批准号: 8318942
• 负责人: FELIX E SCHWEIZER
• 金额: $ 3万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8318942
• 关键词: Address; Affect; Alzheimer' s Disease; Area; Attention; Base of the Brain; Brain; Brain Diseases; Calcium; Commit; Communication; Communities; Development; Disease; Drug Addiction; Ear; Equilibrium; Eye; Fostering; Gender; Goals; Health; Human; International; Joints; Mental Retardation; Mental disorders; Mind; Modification; Molecular; Molecular Structure; Mood Disorders; Nervous system structure; Neurodegenerative Disorders; Neurons; New Hampshire; Oral; Parkinson Disease; Participant; Peripheral; Publishing; Regulation; Request for Proposals; Research; Research Personnel; Resolution; Resort; Role; Schedule; Schizophrenia; Scientist; Sensory; Series; Signal Transduction; Staging; Structure; Synapses; Synaptic Transmission; Synaptic plasticity; autism spectrum disorder; base; career; innovation; lectures; meetings; nanoscale; nervous system disorder; novel; posters; postsynaptic; preference; presynaptic; programs; symposium; therapy design; transmission process

DESCRIPTION (provided by applicant): This proposal requests partial support for an international meeting on Synaptic Transmission as part of the Gordon Research Conference series to be held at the Waterville Valley Resort in the mountains of New Hampshire during the week of July 29-August 3, 2012. The broad and long term goal of the conference is to increase our understanding of the fundamental molecular and cellular mechanisms of synaptic transmission. The synapse serves as the basic signaling unit of the nervous system. Synaptic transmission underlies every aspect of brain function and is relevant to most neurological diseases, as well as mental illness and drug addiction. The specific aims of this meeting will be to convene 34 speakers that represent critical areas of synaptic transmission research with a total of 150 participants for a five day conference in a relatively isolated setting. The program will have two keynote lectures and eight sessions that broadly address current issues in the nano-scale structure and molecular machinery of synapses, the regulation of synaptic transmission by calcium, trans-synaptic signaling and postsynaptic modifications. A session devoted to ribbon-type synapses in the eye and ear will highlight structural and functional diversity of synapses. Another session is devoted to the synaptic basis of brain disorders and a meeting will conclude with an integrative session on the role of synapses in circuits. In addition, two evening poster sessions will permit all participants to contribute to these topics. The significance of this application is that the Gordon Research Conference on Synaptic Transmission is a critical component of the yearly series of conferences that propel research in the international community of synaptologists. The health relatedness of this application is that the discussions will define the questions that require experimental resolution of a wide range of devastating brain disorders, including neurodegenerative diseases, schizophrenia, autism spectrum disorders, drug addiction, mood disorders, loss of peripheral sensory function and many others, which are collectively emerging as synapto-pathies.

描述（由申请人提供）：该提案要求在2012年7月29日至8月3日在新罕布什尔州山区的沃特维尔山谷度假村举行的戈登研究会议系列的国际会议，作为戈登研究会议系列的一部分。突触是神经系统的基本信号单元。突触传播是大脑功能的各个方面的基础，与大多数神经系统疾病以及精神疾病和吸毒成瘾有关。这次会议的具体目的是召集34名演讲者，代表突触传播研究的关键领域，共有150名参与者在相对孤立的环境中进行为期五天的会议。该计划将有两个主题演讲和八个课程，这些会议在纳米级结构和突触的分子机制中广泛解决了当前问题，通过钙，反式突触信号传导和突触后修饰来调节突触传播。致力于眼睛和耳朵中的色带突触的会话将突出突触的结构和功能多样性。另一个会议致力于脑部疾病的突触基础，会议将以关于突触在电路中的作用的综合性会议结束。此外，两个晚上的海报会议将允许所有参与者为这些主题做出贡献。该应用程序的重要性是，戈登突触传播研究会议是推动国际突触学家社区研究的年度会议系列的关键组成部分。该应用的健康相关性在于，讨论将定义需要实验性灾难性脑部疾病的问题，包括神经退行性疾病，精神分裂症，自闭症谱系障碍，吸毒，情绪障碍，情绪障碍，外围感觉功能的丧失以及许多其他人，这些功能以及其他许多是型号，这些功能是造型的。