The Impact of Frequency Compression on Cortical Evoked Potentials and Perception

频率压缩对皮质诱发电位和感知的影响

• 批准号: 8454150
• 负责人: Benjamin J Kirby
• 金额: $ 2.89万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-07 至 2014-08-06
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8454150
• 关键词: Acoustics; Address; Adult; Audiology; Auditory Evoked Potentials; Auditory area; Characteristics; Child; Childhood; Clinical; Complex; Computer software; Conflict (Psychology); Custom; Data Compression; Detection; Development; Discrimination; Elderly; Evidence based practice; Evoked Potentials; Feedback; Frequencies; Hearing; Hearing Aids; High-Frequency Hearing Loss; Individual; Infant; Laboratories; Measures; Methods; Outcome Measure; Participant; Perception; Performance; Pilot Projects; Population; Population Heterogeneity; Process; Psychophysiology; Publications; Reporting; Research; Sensorineural Hearing Loss; Series; Simulate; Speech Perception; Speech Sound; Stimulus; Testing; Time; Variant; base; computerized data processing; evidence base; hearing impairment; improved; knowledge base; research study; response; sound; sound frequency; tool

DESCRIPTION (provided by applicant): One of the central challenges in the field of audiology is the verification of optimal hearing aid fitting in infants and young children who cannot reliabl provide detailed subjective feedback about hearing aid settings. The audiologist often must depend on parental report to guide the selection of hearing aid settings and obtaining that information may take weeks or months. Recently, it has been established that cortical auditory evoked potentials (CAEPs), objective recordings of activity in the auditory cortex, may serve as an alternative to parental report for fitting hearing aids. While CAEPs can be used in clinical settings to determine audibility of sound for infants using various hearing aid gain characteristics, at this time, no objective measure exists to guide the selection of optimal frequency compression parameters for an individual hearing aid user. Frequency compression is a hearing aid signal-processing strategy for systematically lowering high frequency sounds that is now commonly enabled for adult and child hearing aid users. It can be effective at increasing the audibility of high frequency speech sounds for individuals with sloping, high frequency hearing loss because it moves those speech sounds from a region of hearing impairment to a region of better hearing. Unfortunately, frequency compression algorithms can also cause a reduction in the spectral contrast between different speech sounds - particularly when more aggressive frequency compression settings are used. The acoustic change complex (ACC) is a variant of traditionally recorded CAEPs and the presence of an ACC is correlated with detection of change in an ongoing stimulus. The ACC may be ideal to evaluate objectively the effects of frequency compression parameters on the representation of spectrally contrasted sounds in the auditory cortex in hearing aid users who are unable to provide subjective feedback on frequency compression settings. The specific aim of this project is to determine the relationship between cortical evoked potentials and psychophysical performance in conditions of frequency compression and hearing loss. A series of three experiments are proposed to address this specific aim. In the first experiment, ACC responses, psychophysical spectral discrimination thresholds, and vowel identification scores will be obtained from normal hearing participants listening to stimuli that have been compressed in frequency using custom software. In the second experiment, these same measures will be completed in normal hearing participants listening to stimuli additionally processed to simulate high frequency hearing loss. Finally, in the third experiment, a heterogeneous group of participants with high frequency sensorineural hearing loss will be tested. The results of these three experiments will describe the relationship between perception and cortical evoked responses in a range of frequency compression conditions, filling a critical gap in our knowledge base and potentially establishing a needed evidence-based objective outcome measure applicable to clinical pediatric hearing aid fitting. PUBLIC HEALTH RELEVANCE: The proposed research will serve to establish relationships between perception and the encoding of sounds in the auditory cortex in conditions of frequency compression. An objective measure of the type proposed may address an unmet need in clinical pediatric hearing aid fitting, resulting in improved audibility and discriminability of sounds by young hearing aid users.

描述（由申请人提供）：听力学领域中的核心挑战之一是验证了无法Reliabl的婴儿和幼儿的最佳助听器配件，他们提供了有关助听器环境的详细主观反馈。听力学家通常必须依靠父母的报告来指导助听器的选择，并获取该信息可能需要数周或数月。最近，已经确定，皮质听觉引起的潜力（CAEP），听觉皮层活动的客观记录，可以作为适合助听器的父母报告的替代方法。虽然CAEP可以在临床环境中使用，以确定使用各种助听器增益特征的婴儿的声音，但目前尚无客观措施来指导为单个助听器用户选择最佳频率压缩参数。频率压缩是一种助听器信号处理策略，用于系统地降低高频声音，这对于成人和儿童助听器使用者通常启用。它可以有效地增加具有倾斜，高频听力损失的人的高频语音声音的可听性，因为它将这些语音从听力障碍区域移动到更好的听力区域。不幸的是，频率压缩算法也可能导致不同语音之间的光谱对比度减少，尤其是当使用更具侵略性的频率压缩设置时。声学变化复合物（ACC）是传统记录的CAEP的变体，ACC的存在与正在进行的刺激中的变化有关。 ACC可以客观地评估频率压缩参数对无法提供频率压缩设置的主观反馈的助听器用户中听觉皮层中频谱对比的声音表示的影响。该项目的具体目的是确定在频率压缩和听力损失条件下皮质诱发电位与心理物理表现之间的关系。提出了一系列三个实验来解决这一特定目标。在第一个实验中，将从正常的听力参与者中获得ACC响应，心理物理频谱歧视阈值和元音识别分数，这些参与者听取使用自定义软件在频率下被压缩的刺激的人。在第二个实验中，这些相同的措施将在正常的听力参与者中完成聆听刺激的刺激以模拟高频听力损失。最后，在第三个实验中，将测试具有高频感官听力损失的异质参与者。这三个实验的结果将描述在一系列频率压缩条件下的感知与皮质诱发反应之间的关系，填补我们的知识基础中的关键空白，并有可能建立适用于临床儿科助听器配件的所需的基于证据的目标结果指标。 公共卫生相关性：拟议的研究将有助于在频率压缩条件下在听觉皮层中的感知与声音编码之间建立关系。提出的类型的客观度量可能解决了临床小儿助听器配件的未满足需求，从而提高了年轻助听器用户对声音的可听性和可辨别性。