Clincal and Translational Science Award

临床和转化科学奖

基本信息

批准号：
8260697
负责人：
REZA NONE SHAKER
金额：
$ 30万
依托单位：
MEDICAL COLLEGE OF WISCONSIN
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2012-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8260697
关键词：
Achievement Acquired Immunodeficiency Syndrome Address Adolescent Adult Affect Agreement Ally Anesthesiology Applications Grants Appointment Area Authorization documentation Award Basic Science Binding Bioethics Biomedical Engineering Biometry Budgets Cardiovascular system Child Childhood Clinic Clinical Clinical Data Clinical Investigator Clinical Research Clinical Sciences Clinical Services Clinical Trials Collaborations Communication Communities Community Health Community Integration Community Participation Community Practice Complement Complex Conflict of Interest Confusion Consultations Country Data Quality Databases Dentistry Dentists Dermatology Development Diabetes Mellitus Diagnostic Discipline Discipline of Nursing Disease Doctor of Philosophy Education Educational workshop Elderly Elements Emergency Medicine Endocrine Engineering Enrollment Ensure Environment Equipment Ethical Issues Ethics Evaluation Event Faculty Family Practice Focus Groups Fostering Fresh Water Funding Future General Population Genetic Genomics Genotype Goals Government Grant Grant Review HIV Infections Health Health Personnel Health Sciences Healthcare Home environment Hospitals Human Genetics Human Genome Project Human Resources IACUC Individual Industry Industry Collaboration Informed Consent Institutes Institution Institutional Review Boards Interdisciplinary Study Interview Knowledge Lead Leadership Letters Link Maintenance Measures Medical Medical center Medicine Mentored Clinical Scientist Development Program Mentors Methodology Methods Modeling Molecular Genetics Monitor Names National Center for Research Resources Newsletter Nurses Obesity Organ Donations Participant Pathology Pathway interactions Patient advocacy Patients Pediatric Hospitals Pediatrics Phenotype Policies Preventive Process Progress Reports Protocols documentation Public Health Recording of previous events Recruitment Activity Reporting Request for Proposals Research Research Design Research Infrastructure Research Institute Research Personnel Research Priority Research Project Grants Research Support Research Training Resources Rest Role Safety Schedule Schools Science Scientist Senior Scientist Series Services Single Nucleotide Polymorphism Site Social Sciences Statistical Data Interpretation Structure Students Suggestion Support System System Technology Time Tissues Training Training Programs Training and Education Training and Infrastructure Transcend Translating Translational Research Translations United States National Institutes of Health Universities Wisconsin Work Workload Writing acronyms authority base bench to bedside biomedical informatics biomedical resource care delivery career development clinical conference clinical effect clinical practice college cost design effective therapy empowered experience falls help-seeking behavior high school human subject human subject protection improved infrastructure development innovation interest medical schools meetings member multidisciplinary nervous system disorder neuroimaging novel operation organizational structure outreach population health pre-doctoral programs prototype respiratory skills social symposium web site

项目摘要

The National institutes of Health's RFA for Clinical and Translational Science Awards has catalyzed the efforts of academic medical institutions to remove impediments to the translation of fundamental discoveries into better health for our citizens and rectify shortages within the clinical and translational workforce. This proposal of the Clinical and Translational Science Institute of Southeast Wisconsin is tailored to the needs and resources of the biomedical enterprise in the region and offers a novel and transformative plan to achieve the above mentioned goals. Building on the long collaborative history among the major academic and healthcare institutions in our area, we have constructed a unique academic-community partnership comprised of the Medical College of Wisconsin, University of Wisconsin-Milwaukee, Marquette University, Milwaukee School of Engineering, Froedtert Hospital, Children's Hospital of Wisconsin, Zablocki VA Medical Center and BloodCenter of Wisconsin, set in the milieu of a large urban community with remarkable ethnic and social diversity. Our proposal brings together the various resources of the partner institutions to identify and address the obstacles that impede the conduct of clinical and translational research in the region. The transforming environment of our CTSI focuses on the interdependency and interrelationship of our research teams and the relationship of the key functions to the rest of the CTSA in their integrating, enabling and effecting roles. To accomplish this transformation, we propose (and have begun to implement during the pre-award years) 1) To develop a distinct "Academic Home" for the discipline of clinical and translational science - the Clinical and Translational Science Institute (CTSI) - which transcends intra-and inter-institutional barrier, empowers experienced leadership to have the authority and resources to promote, facilitate, coordinate and foster the continuum of translational research from bench to bedside (T1), to clinical practices (T2), and to our communities (T3); 2) To increase the number of investigators participating in clinical research through innovative programs within the CTSI; 3) To develop, align, and coordinate infrastructure across institutions to provide our scientists with the resources required for Clinical and Translational research; and 4) To engage clinical practices and the community in research h that enhances public health. Our Community Engagement program is an MCW strength. We will build on an existing network of the Healthier Wisconsin Partnership Program (HWPP) and expertise and resources of our partners in medical, biomedical engineering, dentistry, nursing, social sciences and allied health disiciplines to implement novel community based (T3) research programs. We believe our CTSA model is transferable to other similarly-sized academic research communities across the country.

美国国立卫生研究院的 RFA 临床和转化科学奖促进了学术医疗机构努力消除将基本发现转化为更好的公民健康的障碍，并纠正临床和转化劳动力的短缺。威斯康星州东南部临床和转化科学研究所的这项提案是根据该地区生物医药企业的需求和资源量身定制的，并为实现上述目标提供了新颖的变革性计划。基于我们地区主要学术和医疗机构之间的长期合作历史，我们建立了独特的学术界合作伙伴关系，包括威斯康星医学院、威斯康星大学密尔沃基分校、马凯特大学、密尔沃基工程学院、Froedtert 医院、威斯康星州儿童医院、扎布洛克退伍军人医疗中心和威斯康星州血液中心位于一个具有显着种族和社会多样性的大型城市社区的环境中。我们的提案汇集了合作机构的各种资源，以识别和解决阻碍该地区进行临床和转化研究的障碍。 CTSI 的转型环境侧重于我们研究团队的相互依赖性和相互关系，以及关键职能与 CTSA 其余部分在整合、支持和影响作用方面的关系。为了实现这一转变，我们建议（并已在颁奖前几年开始实施）1）为临床和转化科学学科建立一个独特的“学术之家”——临床和转化科学研究所（CTSI）——超越机构内和机构间的障碍，赋予经验丰富的领导层权力和资源，以促进、促进、协调和促进转化研究从实验室到床边（T1）到临床实践（T2）的连续性，以及到我们的社区（T3）； 2) 通过 CTSI 内的创新项目增加参与临床研究的研究者数量； 3) 开发、协调和协调跨机构的基础设施，为我们的科学家提供临床和转化研究所需的资源； 4) 让临床实践和社区参与增强公共卫生的研究。我们的社区参与计划是 MCW 的优势。我们将利用健康威斯康星州合作伙伴计划 (HWPP) 的现有网络以及我们在医学、生物医学工程、牙科、护理、社会科学和相关健康学科领域合作伙伴的专业知识和资源，实施新型社区 (T3) 研究计划。我们相信我们的 CTSA 模型可以转移到全国其他类似规模的学术研究社区。

项目成果

期刊论文数量（103）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Clostridium difficile infection in hospitalized liver transplant patients: a nationwide analysis.

住院肝移植患者中的艰难梭菌感染：全国范围内的分析。

DOI：
发表时间：
2012-08
期刊：
影响因子：
0
作者：
Ali, Muhammad;Ananthakrishnan, Ashwin N;Ahmad, Shahryar;Kumar, Nilay;Kumar, Gagan;Saeian, Kia
通讯作者：
Saeian, Kia

Characteristics of the residential neighborhood environment differentiate intimate partner femicide in urban versus rural settings.

居住区环境的特征区分了城市和农村环境中杀害亲密伴侣女性的行为。

DOI：
发表时间：
2013-06
期刊：
影响因子：
0
作者：
Beyer, Kirsten M M;Layde, Peter M;Hamberger, L Kevin;Laud, Purushottam W
通讯作者：
Laud, Purushottam W

Feeding dysfunction in children with single ventricle following staged palliation.

单心室儿童分期姑息治疗后的喂养功能障碍。

DOI：
发表时间：
2014-02
期刊：
影响因子：
0
作者：
Hill, Garick D;Silverman, Alan H;Noel, Richard J;Simpson, Pippa M;Slicker, Julie;Scott, Ann E;Bartz, Peter J
通讯作者：
Bartz, Peter J

Evaluation of a peer-led hypertension intervention for veterans: impact on peer leaders.

对退伍军人同伴主导的高血压干预的评估：对同伴领导的影响。

DOI：
发表时间：
2013-06
期刊：
影响因子：
2.4
作者：
Mosack, Katie E;Patterson, Leslie;Brouwer, Amanda M;Wendorf, Angela R;Ertl, Kristyn;Eastwood, Dan;Morzinski, Jeffrey;Fletcher, Kathlyn;Whittle, Jeff
通讯作者：
Whittle, Jeff

Characterization of adolescent prescription drug abuse and misuse using the Researched Abuse Diversion and Addiction-related Surveillance (RADARS(®)) System.

使用研究滥用转移和成瘾相关监测 (RADARS(®)) 系统来描述青少年处方药滥用和误用的特征。