Genomic stability of human pluripotent stem cells

人类多能干细胞的基因组稳定性

• 批准号: 8248880
• 负责人: Paul Hubert Lerou
• 金额: $ 24.9万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8248880
• 关键词: Accounting; Affect; Aneuploidy; Award; Biological; Biological Assay; CDK2 gene; Cell Culture Techniques; Cell Cycle; Cell Cycle Regulation; Cell Cycle Regulation Pathway; Cell Line; Cell division; Cell model; Cells; Cellular biology; Chromosomes; Complement; Coupled; Cyclin E; Cytogenetic Analysis; DNA; DNA Damage; DNA Repair; DNA biosynthesis; Defect; Development; Disease; Embryo; Ensure; Environment; Fibroblasts; Funding; Future; Generations; Genes; Genetic; Genome Stability; Genomic Instability; Germ Cells; Goals; Hematology; Hospital Departments; Human; Imaging Techniques; Imaging technology; Infertility; Institutes; Institution; Instruction; Life; Maintenance; Malignant Neoplasms; Mediating; Mentors; Mentorship; Mitotic; Molecular; Mutation; Pathway interactions; Patients; Pediatric Hospitals; Phase; Pluripotent Stem Cells; Production; RNA Interference; Regulation; Reporter; Research; Research Proposals; Resources; Role; Scientist; Somatic Cell; Stem cells; Syndrome; Systems Biology; Techniques; Telomere Maintenance; Testing; Training; Training Programs; Viral; base; cancer genetics; career; cell fixing; cellular imaging; daughter cell; embryonic stem cell; human embryonic stem cell; improved; induced pluripotent stem cell; insight; knock-down; medical schools; novel; oncology; repaired; response; segregation; self-renewal; senescence; small molecule; stem; stem cell biology; telomere; tool; tumorigenesis