Support for the Charleston Ceramide Conference

支持查尔斯顿神经酰胺会议

基本信息

批准号：
8423722
负责人：
YUSUF AWNI HANNUN
金额：
$ 0.5万
依托单位：
STATE UNIVERSITY NEW YORK STONY BROOK
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-02-01 至 2015-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8423722
关键词：
1,2-diacylglycerol Address Advanced Development Aging Area Atherosclerosis Australia Biochemical Bioinformatics Biological Biology Canada Cancer Biology Cell physiology Cellular biology Ceramides Cerebrosides China Collaborations Computer Retrieval of Information on Scientific Projects Database Development Diglycerides Discipline Disease Distal Enzymes Explosion Faculty Feedback Fostering France Functional disorder Funding Germany Goals Health Human Immune System Diseases Individual Industry Inflammation Inflammatory Information Dissemination Institutes International Investigation Ireland Israel Italy Japan Korea Lead Lebanon Lipids Malignant Neoplasms Mass Spectrum Analysis Metabolic Metabolism Molecular Neoplasm Metastasis Nerve Degeneration Netherlands New Zealand Participant Pathogenesis Pathway interactions Pharmacologic Substance Pharmacology Postdoctoral Fellow Process Proteins Publications Regulation Relative (related person)Research Research Peer Review Research Personnel Role Scientist Seasons Signal Pathway Signal Transduction Spain Sphingolipids Sphingomyelinase Sphingosine Stenosis Techniques Therapeutic Therapeutic Agents Thrombosis Translational Research Travel Trees United States National Institutes of Health Ursidae Family Vascular Diseases Work analog base empowerment experience field study graduate student immunoregulation inhibitor/antagonist inorganic phosphate insight lipid metabolism mathematical model meetings nano next generation novel novel strategies programs skeletal disorder skin disorder sphingosine 1-phosphate symposium tumor progression

项目摘要

ABSTRACT This application seeks partial funding for an upcoming international conference, the fifth Charleston Ceramide Conference (CCC5) to be held March 11-14, 2009 at the Double Tree, Charleston, SC with expected 200 attendees (and approximately the same date in 2011 and 2013). The theme of the conference builds on two decades of investigation that have resulted in an explosion in research centered on bioactive sphingolipids; especially ceramide, sphingosine, sphingosine phosphate (S1P), ceramide phosphate (C1P), and other related lipids (more than 15000 pub med citations to these lipids). Current investigation is beginning to yield significant insight into the roles of bioactive sphingolipids in pathophysiology, including cancer biology, atherosclerosis, inflammation, neurodegeneration, fungal pathogenesis, skin disorders, and skeletal disorders. As a consequence, exciting possibilities for therapeutic applications are emerging based on\ analogs of bioactive sphingolipids and pharmacologic inhibitors. The purpose of the conference is 1) to bring together a wide variety of investigators who either investigate bioactive sphingolipids and/or have come to the realization of the importance of bioactive lipids in their own distinct fields of study; and 2) enable investigators in these areas to overcome the many difficulties usually encountered in studying lipids, their cell biology, their enzymes, and their function. CCC5 aims at bringing together world leaders in these areas of research into a common forum that enhances the exchange and development of ideas. The CCC has pioneered a novel format whereby most presentations are by junior faculty and by post doctoral fellows and graduate students with short presentations (15 min) followed by prolonged discussion (15 min). Senior investigators present keynote addresses, overviews, and oversee the dynamic discussions. Sessions will highlight novel approaches (e.g. sphinoglipidomics, mathematical modeling), cutting edge research, and translational science. The funds requested will be used exclusively to support the conference and travel expenses of junior investigators who will be attending the conference and presenting their work as invited presentations. The requested funds will be invaluable to the support of this conference.

抽象的该申请为即将举行的国际会议的部分资金，即将于2009年3月11日至14日在南卡罗来纳州查尔斯顿的Double Tree举行的第五届Charleston Ceramide会议（CCC5），预计有200名与会者（大约在2011年和2013年的同一日期）。会议的主题是基于二十年的调查，这导致了以生物活性鞘脂为中心的研究爆炸。尤其是神经酰胺，鞘氨酸，磷酸盐磷酸盐（S1P），磷酸神经酰胺（C1P）和其他相关脂质（对这些脂质的15000多个Pub Med引用）。当前的研究开始对生物活性鞘脂在病理生理学中的作用，包括癌症生物学，动脉粥样硬化，炎症，神经变性，真菌发病机理，皮肤疾病和骨骼疾病的作用。结果，基于生物活性鞘脂和药理学抑制剂的\类似物，对治疗应用的令人兴奋的可能性正在出现。会议的目的是1）汇集各种各样的研究人员，他们要么研究生物活性鞘脂和/或已经实现了在自己独特的研究领域中实现生物活性脂质的重要性； 2）使这些领域的研究人员能够克服研究脂质，细胞生物学，酶及其功能时通常遇到的许多困难。 CCC5旨在将这些研究领域的世界领导人汇集到一个共同的论坛，以增强思想的交流和发展。 CCC开创了一种新颖的格式，大多数演讲都是由初级教师和博士后研究员和研究生进行的，介绍短（15分钟），然后进行了长时间的讨论（15分钟）。高级调查人员提出了主题演讲，概述和监督动态讨论。会议将重点介绍新颖的方法（例如，状皮脂肪组学，数学建模），尖端研究和转化科学。要求的资金将专门用于支持将参加会议并作为邀请演讲展示其工作的初级调查人员的会议和旅行费用。要求的资金对于本次会议的支持将是无价的。