Delivering a Dose of Hope: A Faith-Based Program to Increase Older African Ameri

传递一剂希望：一项以信仰为基础的计划，以增加年长的非洲裔美国人的数量

• 批准号: 8358733
• 负责人: Paula M Frew
• 金额: $ 7.75万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8358733
• 关键词: AIDS/HIV problem; Address; Advocacy; Affect; African; African American; Age; Alzheimer' s Disease; American; Area; Asians; Attitude; Behavioral; Belief; Cardiovascular Diseases; Characteristics; Chronic Disease; Church; Clinical; Clinical Research; Clinical Trials; Communicable Diseases; Communication; Communities; Control Groups; Degenerative Disorder; Dementia; Development; Diabetes Mellitus; Dose; Elements; Enrollment; Ethics; Evaluation; Family Caregiver; Goals; Happiness; Health; Hispanics; Housing; Individual; Influenza; Influenza A Virus, H1N1 Subtype; Information Dissemination; Institution; Insurance Coverage; Intervention; Knowledge; Literature; Malignant Neoplasms; Medical Research; Minority; Minority Groups; Outcome; Outcome Study; Participant; Pathway interactions; Pharmaceutical Preparations; Pilot Projects; Pneumonia; Population; Prevalence; Prevention; Prevention Research; Preventive; Printing; Problem Solving; Program Evaluation; Provider; Randomized; Recruitment Activity; Regulation; Research; Research Personnel; Role; Sampling; Scientific Evaluation; Self Efficacy; Shapes; Social Network; Social support; Source; Support System; Testing; Therapeutic; Time; Trust; United States; United States National Institutes of Health; Vaccines; Work; arm; base; cohort; community based participatory research; design; empowerment; evidence base; experience; follow-up; group intervention; health care service utilization; health disparity; innovation; member; metropolitan; post intervention; primary outcome; programs; research study; satisfaction; socioeconomics; success; therapy design; volunteer

DESCRIPTION (provided by applicant): This project presents a unique opportunity to evaluate a community based culture-centered program to increase older (ages e 55 years) black/African Americans' participation in clinical research. "A Dose of Hope," will engage one of the most powerful forces for community and personal behavioral change in the South, African American communities of faith. Few interventions designed to increase racial and ethnic minority participation in clinical research have been subjected to rigorous scientific evaluation let alone those tailored for older Americans. Therefore, a comprehensive assessment of the multifaceted "Dose of Hope" intervention will inform the development, implementation, and evaluation of community-developed interventions on a national level. This project will enroll 2 matched cohorts, of 105 volunteers each, drawn from 6 representative churches across the Atlanta metropolitan area resulting in a sample of 210 participants. Churches will be matched on selected characteristics including denomination type and membership size. The intervention consists of a half-day program with facilitated small group discussions at 3- and 6-month timepoints. The intervention groups will participate in activities that promote knowledge about minorities and their historical experiences in clinical research, group harms, contemporary clinical trial ethics and regulations, and opportunities for community involvement in clinical research. The control groups will receive general printed material about clinical research. All participants will undergo baseline assessment with follow up at 3- and 6- month intervals. The primary outcome of the study will be the difference in proportions of volunteers in the intervention and control groups who enroll in a clinical trial at one-year post-intervention. The results of our study will fill a critical gap in rigorously tested approaches to increase the numbes of older racial and ethnic minorities in clinical trials which will help address health disparities and will further our understanding of the influence of social networks on clinical trials participation. PUBLIC HEALTH RELEVANCE: Participation of older black/African Americans in clinical research studies is much lower compared to whites despite the fact that the group is disproportionately impacted by many chronic, degenerative, and infectious diseases. "A Dose of Hope" was created to increase diversity and participation in research trials through engagement with black/African American communities of faith. Our goal is to understand if the "Dose of Hope" program is effective in achieving greater enrollment of older blacks in clinical studies, and what elements of the program specifically contribute to the realization of greater enrollment of this group.

描述（由申请人提供）：该项目提供了一个独特的机会来评估以社区为基础的以文化为中心的计划，以增加老年人（55 岁以下）黑人/非裔美国人对临床研究的参与。 “一剂希望”将吸引南方非裔美国人信仰社区中最强大的社区和个人行为改变力量之一。很少有旨在增加种族和族裔参与临床研究的干预措施经过严格的科学评估，更不用说那些为美国老年人量身定制的干预措施了。因此，对多方面的“希望剂量”干预措施的全面评估将为国家层面社区制定的干预措施的制定、实施和评估提供信息。该项目将招募 2 个匹配的队列，每组 105 名志愿者，从亚特兰大大都市区的 6 个代表性教堂中抽取，从而获得 210 名参与者的样本。教会将根据选定的特征进行匹配，包括教派类型和成员规模。干预措施包括为期半天的计划，并在 3 个月和 6 个月的时间点进行小组讨论。干预小组将参加一些活动，以促进对少数群体及其在临床研究中的历史经验、群体伤害、当代临床试验伦理和法规以及社区参与临床研究的机会的了解。对照组将收到有关临床研究的一般印刷材料。所有参与者都将接受基线评估，并每隔 3 个月和 6 个月进行一次随访。该研究的主要结果将是干预组和对照组中在干预后一年参加临床试验的志愿者比例的差异。我们的研究结果将填补经过严格测试的方法中的一个关键空白，以增加临床试验中老年种族和少数族裔的数量，这将有助于解决健康差异，并将进一步了解社交网络对临床试验参与的影响。 公共卫生相关性：尽管老年黑人/非裔美国人受到许多慢性、退行性和传染病的影响不成比例，但与白人相比，老年黑人/非裔美国人参与临床研究的比例要低得多。 “希望之药”的创建是为了通过与黑人/非裔美国信仰社区的接触来增加研究试验的多样性和参与度。我们的目标是了解“希望剂量”计划是否能有效地让更多老年黑人参与临床研究，以及 该计划的哪些内容具体有助于提高这一群体的入学率。