University of Rochester Child Neurology Academic Development Program

罗彻斯特大学儿童神经病学学术发展计划

• 批准号: 8490457
• 负责人: JONATHAN W. MINK
• 金额: $ 23.38万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8490457
• 关键词: Anatomy; Brain; Clinical; Clinical Research; Cognitive Science; Communication; Decision Making; Diagnostic; Disease; Epidemiology; Ethics; Faculty; Fostering; Funding; Future; Goals; Grant; Growth; Incubators; Industry; Laboratories; Mentors; Nervous system structure; Neurobiology; Neurologic; Pediatric Neurology; Pharmacology; Physiology; Positioning Attribute; Program Development; Research; Research Ethics; Research Infrastructure; Research Institute; Research Personnel; Resources; Science; Therapeutic; Thinking; Training; Translating; Translational Research; Universities; Writing; base; career; career development; clinically relevant; design; knowledge base; member; neurodevelopment; new technology; programs; skills; sound; success

DESCRIPTION (provided by applicant): Project Summary: The University of Rochester Child Neurology Career Development Program will provide formal program- based career development support for promising junior faculty in child neurology. Our aims are: 1) to give junior faculty in this program the opportunity to transition from mentored trainees to independent investigators in clinical and/or basic neurobiology research; 2) to foster thinking skills and a knowledge base that will allow supported candidates to apply basic neurobiological principles to achieve a mechanistic understanding of disease so they can translate them into therapeutic and diagnostic options for disorders of the developing nervous system; 3) to foster the academic careers of these junior faculty by providing the guidance and framework necessary for the conduct of scientifically sound, ethical, and clinically relevant research in neurobiology with the mentoring necessary for long-term decision-making and career planning as future leaders in academic child neurology. These goals will be achieved during a 3-year program that provides the candidates with the necessary skills to formulate a research plan relevant to disease and design an implementation strategy under the guidance of faculty who have demonstrated research success and mentoring excellence. All supported candidates will participate in formal training in research ethics, career development, grant writing, and scientific communication. The goal is to provide the supported junior faculty members with the skills necessary to establish a research career in neurological science and to move toward independent funding as an investigator with the promise of vigorous professional growth. Support is sought for 3 positions, each for a three year period of support. Training facilities include: laboratories in the departments of Neurology, Pediatrics, Neurobiology & Anatomy, Physiology & Pharmacology, Brain & Cognitive Sciences, and the Center for Neural Development and Disease. The program will take full advantage of the resources and career development infrastructure of the UR Clinical and Translational Research Institute, including access to biostatistical, epidemiologic, and clinical research expertise and cutting-edge novel technologies developed in both academic and industry incubator settings.

描述（由申请人提供）： 项目摘要：罗切斯特大学儿童神经病学职业发展计划将为有前途的儿童神经病学初级教师提供正式的基于计划的职业发展支持。我们的目标是：1）为该项目的初级教师提供从受指导的实习生过渡到临床和/或基础神经生物学研究的独立研究者的机会； 2) 培养思维技能和知识基础，使受支持的候选人能够应用基本的神经生物学原理来实现对疾病的机械理解，以便他们能够将其转化为发育中神经系统疾病的治疗和诊断选择； 3）通过提供进行科学合理、符合伦理和临床相关的神经生物学研究所需的指导和框架，以及作为未来领导者的长期决策和职业规划所需的指导，促进这些初级教师的学术生涯在学术儿童神经学方面。这些目标将在为期 3 年的计划中实现，该计划为候选人提供必要的技能，以制定与疾病相关的研究计划，并在已证明研究成功和卓越指导的教师的指导下设计实施策略。所有受支持的候选人都将参加研究伦理、职业发展、资助写作和科学传播方面的正式培训。目标是为受支持的初级教员提供建立神经科学研究生涯所需的技能，并作为研究者走向独立资助，并有望实现蓬勃的专业发展。 寻求 3 个职位的支持，每个职位的支持期限为三年。培训设施包括：神经病学、儿科、神经生物学和解剖学、生理学和药理学、脑和认知科学以及神经发育和疾病中心的实验室。该项目将充分利用UR临床和转化研究所的资源和职业发展基础设施，包括获得生物统计、流行病学和临床研究专业知识以及在学术和行业孵化器环境中开发的尖端新技术。

项目成果

Neurodevelopmental outcomes after neonatal cardiac surgery: Role of cortical isoelectric activity.

新生儿心脏手术后的神经发育结果：皮质等电活动的作用。

• DOI: 10.1016/j.jtcvs.2015.10.065
• 发表时间: 2016
• 期刊: The Journal of thoracic and cardiovascular surgery
• 作者: Seltzer,Laurie;Swartz,MichaelF;Kwon,Jennifer;Burchfiel,James;Cholette,JillM;Wang,Hongyue;Sweeney,Dawn;Adams,HeatherR;Meagher,Cecilia;Angona,Ron;Guillet,Ronnie;Alfieris,GeorgeM
• 通讯作者: Alfieris,GeorgeM

Utility of the diagnostic interview schedule for children for assessing Tourette syndrome in children.

儿童诊断访谈时间表用于评估儿童抽动秽语综合征的实用性。

• DOI: 10.1089/cap.2013.0128
• 发表时间: 2014
• 期刊: Journal of child and adolescent psychopharmacology
• 影响因子: 1.9
• 作者: Lewin,AdamB;Mink,JonathanW;Bitsko,RebeccaH;Holbrook,JosephR;Parker-Athill,ECarla;Hanks,Camille;Storch,EricA;Augustine,ErikaF;Adams,HeatherR;Vierhile,AmyE;Thatcher,AlyssaR;Murphy,TanyaK
• 通讯作者: Murphy,TanyaK

Intraoperative electroencephalography predicts postoperative seizures in infants with congenital heart disease.

术中脑电图可预测先天性心脏病婴儿的术后癫痫发作。

• DOI: 10.1016/j.pediatrneurol.2013.12.017
• 发表时间: 2014
• 期刊: Pediatric neurology
• 影响因子: 3.8
• 作者: Seltzer,LaurieE;Swartz,Michael;Kwon,JenniferM;Burchfiel,James;Alfieris,GeorgeM;Guillet,Ronnie
• 通讯作者: Guillet,Ronnie

SUICIDAL THOUGHTS AND BEHAVIORS IN CHILDREN AND ADOLESCENTS WITH CHRONIC TIC DISORDERS.

患有慢性抽动障碍的儿童和青少年的自杀想法和行为。

• DOI: 10.1002/da.22357
• 发表时间: 2015
• 期刊: Depression and anxiety
• 影响因子: 7.4
• 作者: Storch,EricA;Hanks,CamilleE;Mink,JonathanW;McGuire,JosephF;Adams,HeatherR;Augustine,ErikaF;Vierhile,Amy;Thatcher,Alyssa;Bitsko,Rebecca;Lewin,AdamB;Murphy,TanyaK
• 通讯作者: Murphy,TanyaK

Design of a Multisite Study Assessing the Impact of Tic Disorders on Individuals, Families, and Communities.

• DOI: 10.1016/j.pediatrneurol.2016.10.017
• 发表时间: 2017-03
• 期刊: Pediatric neurology
• 影响因子: 3.8
• 作者: Augustine EF;Adams HR;Bitsko RH;van Wijngaarden E;Claussen AH;Thatcher A;Hanks CE;Lewin AB;O'Connor TG;Vierhile A;Danielson ML;Kurlan R;Murphy TK;Mink JW
• 通讯作者: Mink JW