BIOINFORMATICS CORE

生物信息学核心

• 批准号: 8167528
• 负责人: DAVID L DYER
• 金额: $ 13.47万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167528
• 关键词: Archives; Award; Bioinformatics; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Data; Data Base Management; Data Set; Databases; Funding; Gene Expression; Grant; Individual; Institution; Microarray Analysis; Online Systems; Process; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Writing; repository; research study; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A major responsibility will continue to be the database management and analysis of microarray data. We also will coordinate our efforts with the accessory microarray cores located at OMRF, OU Norman, OSU, and TU, as needed by the PUI investigators that use those facilities. We will promote the use of a common set of tools using the MIAMI and MAGE standards, and will act as a central repository of data for submission to the national repository Gene Expression Omnibus (GEO); MAGE will be essential for this effort. We will write scripts necessary to export BASE-archived data in the SOFT format used by the microarray data archive GEO at NCBI. GEO is a MIAME-compliant database at NCBI where investigators can submit the results from individual microarray experiments to GEO using a web-based form. Alternatively, large microarray data sets can be submitted in batch using the NCBI SOFT convention. We will continue to provide support for both submission processes to investigators of INBRE and COBRE awards and will help the accessory core facilities perform these functions as well.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 主要职责将继续是微阵列数据的数据库管理和分析。 我们还将根据使用这些设施的 PUI 研究人员的需要，与 OMRF、OU Norman、OSU 和 TU 的附属微阵列核心协调我们的工作。 我们将推广使用采用 MIAMI 和 MAGE 标准的通用工具集，并将作为数据中央存储库，提交给国家基因表达综合存储库 (GEO)； MAGE 对于这项工作至关重要。 我们将编写必要的脚本，以 NCBI 的微阵列数据存档 GEO 使用的 SOFT 格式导出 BASE 存档数据。 GEO 是 NCBI 的一个符合 MIAME 标准的数据库，研究人员可以使用基于网络的表格将各个微阵列实验的结果提交给 GEO。 或者，可以使用 NCBI SOFT 惯例批量提交大型微阵列数据集。 我们将继续为 INBRE 和 COBRE 奖项的调查人员提供提交流程支持，并将帮助附属核心设施履行这些职能。