FASEB Summer Research Conference: Phospholipid Metabolism: Disease, Signal Transd

FASEB 夏季研究会议：磷脂代谢：疾病、信号传输

• 批准号: 8457031
• 负责人: SUZANNE E BARBOUR
• 金额: --
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8457031
• 关键词: Academy; Area; Atherosclerosis; Award; Basic Science; Biochemistry; Biology; Biomedical Research; Biophysics; Cell Nucleus; Cell physiology; Collaborations; Communities; Development; Diabetes Mellitus; Discipline; Disease; Ensure; Enzymes; Female; Funding; Funding Applicant; Grant; Healthcare; Individual; Inflammation; Institutes; International; Knockout Mice; Laboratories; Lipids; Malignant Neoplasms; Mass Spectrum Analysis; Membrane; Membrane Protein Traffic; Metabolism; Molecular; Nuclear; Phospholipase; Phospholipase A2; Phospholipid Metabolism; Phospholipids; Physiological; Process; Publications; Recruitment Activity; Research; Research Peer Review; Research Personnel; Signal Transduction; Sphingolipids; Transcriptional Regulation; Translational Research; Travel; United States National Institutes of Health; Vermont; abstracting; base; cost; interest; lipid metabolism; meetings; member; multidisciplinary; posters; protein transport; response; symposium; tool

DESCRIPTION (provided by applicant): Funds are requested to support for the 2012 (July 15-20, Vermont Academy), 2014, and 2016 offerings of the FASEB Summer Research Conference entitled: Phospholipid Metabolism: Disease, Signal Transduction, and Membrane Biophysics. The subject area receives considerable support from the NIH with nearly 500 active projects sustained by funds provided by NIH institutes and has generated ~5000 peer reviewed research publications each year in the past decade. This is an on-going conference that was first offered as a "phospholipases" meeting in 1988. The conference has changed substantially from its original offering and now encompasses most of the major disciplines related to phospholipid metabolism, phospholipid signaling, and membrane biophysics. Furthermore, the conference has become more relevant to members of the general biomedical research community, as research in the field had become increasingly multidisciplinary. In large part, this has been driven by the availability of molecular and pharmacological tools for enzymes that metabolize phospholipids and by availability of knockout mice lacking these enzymes. This has allowed researchers in other areas to investigate the involvement of phospholipids in specific cellular functions as well as physiological and pathophysiological processes. The meeting highlights advances in these areas and also focuses on lipid/ protein trafficking, nuclear lipid signaling, and oxidized phospholipids, disciplines that have not been major foci in the past. The shift in emphasis not only underscores the research interests of the organizers, but is also a deliberate attempt to broaden the focus of the meeting to engage new researchers who might not otherwise attend the conference. The meeting is organized into eight themes, which feature 30- minute talks by invited speakers who are leaders in the field and 15-minutes talks to be chosen from among submitted abstracts. Two poster sessions are included as well as an informal discussion of the "state of the art" of lipidomics/ lipid mass spectrometry led by Core Directors i the LIPID MAPS group. The Organizers will invite young investigators to present the 15-minute talks and will use these slots to recruit additional female speakers and speakers from underrepresented groups. Funds from this proposal will be used to provide travel awards for such individuals and also to enable them to bring members of their laboratories to the conference.

描述（由申请人提供）：要求资金支持2012年（7月15日至20日，佛蒙特州学院），2014年和2016年FaseB夏季研究会议的2016年产品，标题为：磷脂代谢：疾病，信号转导和膜生物物理学。该学科领域获得了NIH的大量支持，其中近500个由NIH Institutes提供的资金维持的活跃项目，并且在过去十年中每年产生了约5000个同行审查的研究出版物。这是一次正在进行的会议，最初是在1988年作为“磷脂酶”会议提供的。该会议已从其原始产品中发生了重大变化，现在涵盖了与磷脂代谢，磷脂信号传导和膜生物物质学有关的大多数主要学科。此外，随着该领域的研究变得越来越多学科，会议已经与一般生物医学研究界的成员更加相关。在很大程度上，这是由代谢磷脂和缺乏这些酶的敲除小鼠的可用性的分子和药理工具驱动的。这使其他领域的研究人员能够研究磷脂在特定的细胞功能以及生理和病理生理过程中的参与。这次会议强调了这些领域的进步，还集中于脂质/蛋白质运输，核脂质信号传导和氧化的磷脂，过去并非主要焦点的学科。重点的转变不仅强调了组织者的研究兴趣，而且还是旨在扩大会议重点以吸引可能不会参加会议的新研究人员的焦点。这次会议分为八个主题，由邀请的演讲者进行了30分钟的会谈，这些演讲者是该领域的领导者，并从提交的摘要中选择了15分钟的会谈。包括两个海报会议，以及对脂质组学/脂质质谱的“最先进的状态”的非正式讨论。组织者将邀请年轻的调查人员介绍15分钟的会谈，并将使用这些插槽来招募来自代表性不足的团体的其他女性演讲者和演讲者。该提案的资金将用于为这些人提供旅行奖，并使他们能够将实验室成员带入会议。