MECHANISMS OF INCREASED ANDROGEN PRODUCTION AMONG PCOS WOMEN

多囊卵巢综合征女性雄激素分泌增加的机制

• 批准号: 8166881
• 负责人: R JEFFREY CHANG
• 金额: $ 0.12万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166881
• 关键词: Adrenal Glands; Androgens; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Human Chorionic Gonadotropin; Institution; Insulin; Output; Production; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; Woman; granulosa cell; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 1. Determine the effect of FSH-stimulated granulosa cells on androgen responses to hCG in PCOS women. 2. Determine the contribution of adrenal androgen production to total androgen output in women with PCOS. 3. Determine the role of insulin on basal and stimulated androgen production in women with PCOS.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 1. 确定 FSH 刺激的颗粒细胞对 PCOS 女性中雄激素对 hCG 反应的影响。 2. 确定患有 PCOS 的女性肾上腺雄激素生成量对雄激素总量的贡献。 3. 确定胰岛素对 PCOS 女性基础雄激素和刺激雄激素产生的作用。