2013 Mammalian DNA Repair Gordon Research Conference and Gordon Research Seminar

2013年哺乳动物DNA修复戈登研究大会暨戈登研究研讨会

• 批准号: 8450407
• 负责人: TANYA T PAULL
• 金额: $ 0.9万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8450407
• 关键词: Address; Aging; Area; Caliber; California; Cancer Biology; Cancer Etiology; DNA; DNA Damage; DNA Repair; Disease; Double Strand Break Repair; Educational workshop; Excision Repair; Faculty; Feedback; Genomic Instability; Goals; Health; Hour; Human; International; Learning; Malignant Neoplasms; Mismatch Repair; Nerve Degeneration; Neurodegenerative Disorders; Oral; Participant; Postdoctoral Fellow; Proteins; Request for Proposals; Research; Role; Schedule; Signal Transduction; Time; abstracting; base; cancer therapy; graduate student; human disease; meetings; peer; planetary Atmosphere; posters; public health relevance; response; symposium; translational approach

DESCRIPTION (provided by applicant): This proposal requests partial support for an international meeting on Mammalian DNA Repair, a Gordon Research Conference that is held every other year and will be held in Ventura, California, Feb 10-15, 2013. The goals of the conference are to increase our understanding of the mechanisms of DNA repair and signaling and how they influence human health, with particular emphasis on cancer biology and neurodegenerative diseases. The meeting will bring together 37 invited speakers with expertise in all of the major areas of DNA repair and damage responses, including excision repair, double-strand break repair, and mismatch repair, as well as DNA damage-induced signaling and mechanisms of damage recognition at replication forks. We will also have sessions focused on the role of DNA damage response proteins in genomic instability as it relates to cancer, and a few speakers will address translational approaches that utilize DNA repair targets in synthetic lethality approaches. There will be 9 short talks chosen from abstracts, and 4 two-hour poster sessions that will allow all of the participants to interact in an informal setting. In addition, tis is the first year that this conference will also host a Gordon Research Seminar prior to the meeting, February 9 -10, 2013 which is a two-day workshop for graduate students and postdoctoral fellows to learn the basics of the field, to have the opportunity to give talks, and t get feedback about their research and their presentations from their peers. The Mammalian DNA Repair GRC is a very significant meeting in this field because of the high caliber of speakers who attend, the intimate scale of the meeting, and the fact that this meeting is widely known as one that propels the research in DNA repair internationally. The application is extremely relevant to human health and disease in its focus on cancer etiology, cancer treatment, neurodegeneration, and aging.

描述（由申请人提供）：该提案请求对哺乳动物 DNA 修复国际会议提供部分支持，该会议是戈登研究会议，每隔一年举行一次，将于 2013 年 2 月 10 日至 15 日在加利福尼亚州文图拉举行。此次会议旨在加深我们对 DNA 修复和信号传导机制以及它们如何影响人类健康的理解，特别强调癌症生物学和神经退行性疾病。会议将汇集 37 名受邀演讲者，他们在 DNA 修复和损伤反应的所有主要领域拥有专业知识，包括切除修复、双链断裂修复和错配修复，以及 DNA 损伤诱导的信号传导和损伤识别机制在复制叉处。我们还将举办一些会议，重点讨论 DNA 损伤反应蛋白在与癌症相关的基因组不稳定性中的作用，一些演讲者将讨论在合成致死方法中利用 DNA 修复靶点的转化方法。将从摘要中选出 9 场简短演讲，以及 4 场两小时的海报会议，让所有参与者在非正式的环境中进行互动。此外，今年会议还将在2013年2月9日至10日的会议之前举办戈登研究研讨会，这是一个为期两天的研讨会，供研究生和博士后研究员学习该领域的基础知识，有机会进行演讲，并从同行那里获得有关他们的研究和演示的反馈。哺乳动物DNA修复GRC是该领域一次非常重要的会议，因为与会的演讲者水平很高，会议规模宏大，而且该会议被广泛认为是推动国际DNA修复研究的会议。该应用程序与人类健康和疾病极其相关，重点关注癌症病因学、癌症治疗、神经退行性疾病和衰老。