Translational Proteomics: Biology, Technology and Clinical Advances

转化蛋白质组学：生物学、技术和临床进展

• 批准号: 8529089
• 负责人: DANIEL Wanyui CHAN
• 金额: $ 2万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-05 至 2014-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8529089
• 关键词: Address; Affect; Animal Model; Area; Automobile Driving; Baltimore; Biological; Biological Assay; Biological Markers; Biology; Biosensor; Biotechnology; Cardiovascular Diseases; Cell physiology; Cities; Clinic; Clinical; Coffee; Collaborations; Communicable Diseases; Complement; Country; Development; Diagnostic; Disabled Persons; Discipline; Disease; Early Diagnosis; Educational Activities; Educational workshop; Faculty; Fostering; Funding; Future; Geographic Locations; Goals; Government; Growth; Health; Hearing; Home environment; Hospitals; Human; Institutes; Intervention; Laboratories; Learning; Liquid substance; Location; Mails; Malignant Neoplasms; Maryland; Mass Spectrum Analysis; Medical Device; Metabolism; Methods; Mid-Atlantic Region; Minority; Minority Groups; Minority-Serving Institution; Mission; Oral; Participant; Persons; Population; Postdoctoral Fellow; Protein Microchips; Proteins; Proteome; Proteomics; Records; Recruitment Activity; Research; Research Institute; Research Personnel; Role; Scientist; Signal Pathway; Site; Societies; Solutions; Staging; Students; Technology; Thinking; Time; Translating; Translations; Underrepresented Minority; United States; United States National Institutes of Health; Universities; Validation; Woman; abstracting; base; career; career development; clinical application; clinical assay development; clinical practice; design; effective therapy; graduate student; handicapping condition; human disease; human tissue; innovation; insight; interest; meetings; member; multidisciplinary; new technology; novel; operation; outcome forecast; posters; professor; prognostic; programs; public health relevance; social; symposium; translational medicine

DESCRIPTION (provided by applicant): We request partial funding support for operation of the 2013 Annual Meeting of the United States Human Proteome Organization (US-HUPO) entitled "Translational Proteomics: Biology, Technology and Clinical Advances", to be held March 10-13, 2013 in Baltimore, Maryland. Since the first US HUPO meeting in 2005, this venue has been and continues to be a vital conference for the highly interdisciplinary scientific field of proteomics, particularly as directed towards biological and clinical questions. US-HUPO is a unique meeting of scientists because it truly reflects the multidisciplinary interactions that have allowed proteomic researchers to approach and solve sophisticated biomedical problems. The US-HUPO meeting endeavors to promote the clinical application and translation of diverse technological platforms including mass spectrometry, protein microarrays, biosensors, clinical assays to biomarker discovery and validation for diagnostic, prognostic and treatment purposes. The US-HUPO conference is heavily attended and has always attracted first-rate speakers in this field. The 2013 Annual Meeting will again bring together an outstanding and diverse group of scientists at the forefront of proteomics. Invited speakers in the symposium will explicitly discuss applications relevant to a wide range of diseases including cardiovascular disease, cancer, and infectious diseases. As technological advances made in the recent years are of critical importance in enabling scientists to more effectively address biological problems, the technological future of proteomics will also be a hallmark of the meeting. The topics chosen will educate participants on the latest, most effective technologies and methods, illustrate successful translation of these technologies into the clinic, and highlight new directions and grand challenges for the future of this field. Interactive panel discussions will be held on key topics in order to encourage a robust dialogue between speakers and meeting participants to discuss critical goals for the future in proteomics, outline anticipated obstacles, and brainstorm solutions. This year US-HUPO will continue highly successful parallel Career Development sessions in Biology, technology and clinical advances, to provide early stage investigators with crucial insights into growth areas in proteomics and strategies for professional development. The poster sessions will also offer a more informal exchange of scientific ideas and advances. Ample time will be devoted to social venues for attendees to meet each other and establish new contacts and collaborations. Currently, 30% of the invited speakers are either women or members of minority groups. Once the program is completed with selections from submitted abstracts, we expect to have at least 35% women and minority speakers, and at least 35% early stage investigators (assistant professors, post-docs and/ graduate students). Attendance is expected to be 350-450 participants, including 100-150 students/post-docs. Registration is not restricted, and all interested persons may attend. A special effort will be made to recruit minorit and industrial participants; the latter should be readily achievable given the central geographic location of Baltimore in the East coast. Participants will present posters on new findings each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, over 28 poster presentations that complement the themes of the meeting will be selected for short oral presentations with an increased time to 15 minutes from 10 minutes during the past meetings. Finally, it is important to note that, preceding the meeting, US-HUPO offers several Half-Day short courses on contemporary topics in proteomics.

描述（由申请人提供）：我们要求为2013年3月10日至13日在马里兰州巴尔的摩举行，要求对2013年美国人类蛋白质组组织（US-HUPO）的运营进行部分资金支持。自2005年美国第一次HUPO会议以来，该场所一直是并继续是高度跨学科的蛋白质组学科学领域的重要会议，尤其是针对生物学和临床问题。 US-HUPO是科学家的独特会议，因为它确实反映了多学科的互动 允许蛋白质组学研究人员解决并解决复杂的生物医学问题。美国 - 赫普（Us-Hupo）的努力旨在促进各种技术平台的临床应用和翻译，包括质谱，蛋白质微阵列，生物传感器，生物标志物发现的临床测定以及诊断，预后和治疗目的的验证。美国 - 赫普（Us-Hupo）会议参加了大量参加，并且一直吸引着该领域的一流演讲者。 2013年的年度会议将再次汇集一群杰出而多样的科学家，处于蛋白质组学的最前沿。研讨会上的受邀演讲者将明确讨论与多种疾病有关的应用，包括心血管疾病，癌症和传染病。随着近年来技术进步在使科学家更有效地解决生物学问题方面至关重要，蛋白质组学的技术未来也将成为会议的标志。所选的主题将教育参与者有关最新，最有效的技术和方法的教育，这说明了这些技术的成功翻译为诊所，并突出了该领域未来的新方向和巨大的挑战。互动小组讨论将在关键主题上进行，以鼓励演讲者和会议参与者之间进行牢固的对话，以讨论蛋白质组学，概述预期障碍和头脑风暴解决方案的关键目标。今年，US-HUPO将继续在生物学，技术和临床进步方面取得非常成功的平行职业发展会议，为早期研究人员提供对蛋白质组学和专业发展策略的增长领域的重要见解。海报会议还将提供更非正式的科学思想和进步交流。充足的时间将用于社交场所，供与会者见面并建立新的联系和合作。目前，有30％的受邀演讲者是妇女或少数群体的成员。一旦该计划完成了提交摘要的选择，我们预计至少有35％的妇女和少数派发言人，以及至少35％的早期调查人员（助理教授，研究生和/研究生）。出勤率预计为350-450名参与者，包括100-150名学生/毕业后。注册不受限制，所有感兴趣的人都可以参加。将为招募少数人和工业参与者做出特别的努力；鉴于巴尔的摩在东海岸的中心地理位置，后者应该很容易实现。参与者每天下午都会在新发现上介绍海报。重要的是，该会议为年轻的研究人员提供了一个论坛，以查看基本科学探究与科学方法在设计人类疾病有效干预措施上的应用之间的联系。为了强调这一目标，将选择与会议主题相辅相成的28多个海报演示文稿，以进行简短的口头演示，从过去的会议期间的10分钟开始增加时间到15分钟。最后，重要的是要注意，在会议之前，Us-Hupo提供了几门关于蛋白质组学当代主题的半天简短课程。